Assistant Quality Control

Manoj Ganesh

***-** **** ******, ***** Park, NY 11417

( 718-***-****; ( **********@*****.***; [pic]

www.linkedin.com/in/manojganesh/

PROFILE

. PhD Materials Chemistry with 2 years of proactive startup skill

experience including project management, R&D, client management,

technology transfer, training, fund raising, administrative operations &

problem solving.

. Research experience in the field of polymer chemistry, biodegradable

polymer, enzyme immobilization, bio-catalysis, biotransformation, protein

purification, kinetic studies, and drug delivery.

. Leader and group coordinator for lab safety (Certified Supervisor) and

inventory management.

. Strong communication and presentation skills.

. Publications include 5 journal articles, 1 book chapter and 1 patent

awarded.

. Awards include ACS Award for Excellence in Graduate Polymer Research

(2010); Prof. Turner Alfrey Prize (2010) & Outstanding Alumni Award

(Batch of 2006).

. 5 Conference Proceedings in National and Regional conferences and

meetings.

Professional Experience

Research Scientist (SyntheZyme LLC)

6/2012 -

present

Job Responsibilities:

. Principal Investigator in contract R&D projects with leading industries.

Product development, co-ordinate research, document findings,

troubleshoot, on-site training & scale up development.

Achievements:

. Synthesis of novel monomers, oligomers for polymerization

(Polycondensation, Trans-esterification & Polyesterification) reactions

by implementing immobilized enzyme technology used for commercial

applications.

EDUCATION

PhD in Materials Chemistry, Polytechnic Institute of NYU, Brooklyn, NY

2006 - 2012

B.Tech in Polymer Technology, Anna University, Chennai, India

2002 - 2006

ACADEMIC Experience

Graduate Research Assistant (NYU-POLY)

12/2006 -

6/2012

Job Responsibilities:

. Conducted, Developed and Executed R&D projects funded by NSF Center for

Biocatalysis and bi-annual evaluation by industry partners.

1. EMBEDDING ENZYMES IN POLYMER (Macromolecules 2009, Polymer 2012 &

Patent awarded) 2006 - 2011 Objective:

Develop a unique method to control lifetime of polymer materials.

Achievements:

. Designed and Developed methods to enable solublization of enzymes in

organic media in order to disperse them within polymer matrices.

. Selected enzymes capable of catalyzing hydrolysis of the polymer matrix.

. Evaluated enzyme-catalyzed polymer hydrolysis by determining changes in

molecular weight averages, protein leaching from the matrix, and

degradation products formed.

2. ENZYME TRIGGER

2011 - 2012

Objective:

Develop a suitable trigger to dynamically control lifetime of polymer

materials.

Achievements:

. Constructed enzyme entraped inside nanocapsules using the layer-by-layer

self-assembly method.

. Evaluated enzyme activity and stability of enzymes upon using ultrasound

as a trigger.

3. MICROCAPSULES

2011 - 2012

Objective:

Develop a drug loaded polymeric microcapsule to be injected to the

pancreatic tumor

Achievements:

. Lead scientist on a team of doctors, students and scientist for co-

ordinating and conducting research on encapsulation of drugs in

microparticles for pancreatic cancer treatment.

. Encapsulated enzymes in microspheres for dispersion within polymeric

matrices.

4. ENZYME LITHOGRAPHY (Biomacromolecules 2013)

2010 - 2012

Objective:

Create arbitrary patterns using enzyme.

Achievements:

. Developed a new method of micro-contact printing of enzymes.

. Micron size patterns and high fidelity patterns of the master template.

Graduate Teaching Assistant (NYU-POLY)

7/2006 -

6/2007

. Organic chemistry and General chemistry teaching assistant for

undergraduate students.

Research Intern

5/2004 - 6/2004

. Internship in "POLYTRUSIONS" and "HiTECH PLASTICS".

. Skills acquired include extrusion molding for production of PVC pipes and

injection molding of pens.

. Quality control by using ASTM standard testing methods.

ANALYTICAL EXPERTISE

. Hands on experience and interpretation proficiency of analytical

equipment such as Differential Scanning Calorimetry (DSC), Absorption

Spectroscopy, Dynamic Light Scattering, Experion automated Gel

Electrophoresis, Gel Permeation Chromatography (GPC), NMR, Coulter

particle size analyzer, Scanning Electron Microscopy (SEM), Confocal laser

microscopy.

AWARDS & HONORS

Publications

. Ganesh, M.; Dave, R.N.; L'Amoreaux, W.; Gross, R.A. "Embedded Enzymatic

Biomaterial Degradation" Macromolecules, 42 (18), pp 6836-6839 (2009).

. Gross, R.A.; Ganesh, M.; W Lu. Enzyme-catalysis breathes new life into

polyester condensation polymerizations. Trends in Biotechnology (2010)

Ganesh, M.; Gross, R.A. "Embedded Enzymatic biomaterial degradation: Flow

conditions & relative humidity", Polymer, (2012)

. Z Marwil, A Asgharpour, M Ganesh, J Ling, A Stanek, R Gross, F Gress, L

Martello-Rooney. "Drug eluting microparticles for the treatment of

pancreatic cancer", Pancreatology, 13 (2) pp. e52-e53 (2013).

. Ganesh, M.; Nachman J.; Zhantong M.; Lyons A.; Rafailovich, M; Gross,

R.A. "Patterned Enzymatic Degradation of Poly(?-caprolactone) by High-

Affinity Microcontact Printing and Polymer Pen Lithography",

Biomacromolecules, (2013).

Book Chapter

. Embedding Enzymes To Control Biomaterial Lifetime Ganesh, Manoj ;

Gross, Richard

Green Polymer Chemistry: Biocatalysis and Biomaterials. January 1,

2010, 375-384

PATENT Awarded

. Ganesh, M.; Dave, R.N.; Martin, A.; Gross, R.A. "Embedded Enzymes in

Polymers to regulate their degradation rate", 12/187949 (2008)

AWARDS

. ACS Award for Excellence in Graduate Polymer Research (2010) awarded at

the 239th ACS National Meeting, California upon nomination from the

faculty of Polytechnic Institute of NYU.

. Prof. Turner Alfrey Prize (2010) awarded by Polytechnic Institute of

NYU in recognition for contributing significantly to the programs and

activities of the University in the pursuit of academic excellence.

. Distinguished Research Fellowship (2006 - 2007), Chemical and

Biological Science Department, Polytechnic Institute of NYU.

. Outstanding Alumni Award (Batch of 2006) awarded by Crescent

Engineering College in recognition to honour Outstanding Alumni of

Department of Polymer Technology.

Recommendations: Available upon request

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