EXECUTIVE SUMMARY

Research & Development – Baxter Healthcare Corporation (Contractor)

Solution preparation, data collection, and statistical analysis of Baxter products at various concentrations using Low Field NMR spectrometry; completed notebook summaries for NMR experiments

Comparison study of the Low Field NMR instrument at different total data acquisition times

Revised a method for testing various formulations for Baxter renal solutions

Assisted with a cost analysis to determine feasibility of using Low Field NMR spectrometry within Baxter manufacturing plants

Proficient in the use of the IDBS Electronic Laboratory Notebook for data recording

Classroom training in ERES, Good Laboratory Practices (GLP), Good Documentation Practices (GDP)

Completed many training modules in ISOtrain – Analytical Method Development & Validation, Safety, Instrument Operation, Calibration, and Maintenance, Cybersecurity, TcU (a document archival system); Read many GMP, GQP, GQUAL, MPP, SOP documents; familiar with ICH guidelines

Prepared chlorine solutions for a Point of Care project and standard solutions for the elemental impurities group; calibrated micropipettes for the elemental impurities group

Data analysis; verification of protocols, final reports, risk assessments; technical writing of protocols, final reports, validation summaries, and amendments for clinical documentation of trace metal impurities in Baxter products; uploaded documentation to Sharepoint and Tracker sites; reviewed SOPs

Verification and validation of filter packs to remove chlorine from a Point of Care Water Device to be used in clinical trials for peritoneal dialysis – preparation and analysis of water samples, writing of protocols and final reports; analysis of filter pack FAPQ polymer via Bruker 500 MHz NMR

Completed Ph.D. in Chemistry - Research in Photodynamic Therapy (PDT) for Cancer

Synthesis of two phenothiazine trimers for use as photosensitizers for PDT

Prepared a chlorin e6 (Ce6) complex using target-directed synthesis with a PEG-Folate linker

Performed cell based assays to assess viability of HeLa cells inoculated with Ce6 complex

Compound purification by Flash and Size Exclusion Chromatography

Characterization, spectral analysis and interpretation using 1H / 13C, COSY/HSQC NMR, FT- IR, UV-Vis,

HPLC-MS, LC-MS/MS; Operated NMR, FT-IR, UV-Vis, HPLC-MS, CE, GC-MS, AA, and IC instrumentation

Method Development using Capillary Electrophoresis to assess resolution of organic acid contaminants in circuit board manufacture

Developed a training manual detailing operation and troubleshooting techniques for HPLC-MS (ion trap)

Lead researcher in a collaborative project – interfaced with organic chemists, biochemists, biologists, analytical chemists, physicists, NMR and MS specialists, graduate students, and chemical and equipment suppliers to maximize productivity

Performed diagnostic procedures using ELISA techniques for determination of Rubella,

Rotavirus, and Legionnaires Disease

Medical Writing – Developed and taught a curriculum of Human Anatomy and Basic Pathology while working as a Medical Technologist at Mercy Hospital

Proficient in the use of Microsoft Excel, Word, PowerPoint, and Adobe Acrobat

Presented Research at Local and International Conferences

Presented research at EuCheMS 2012 Conference in Prague, Czech Republic; awarded by ACS

Presented research at the American Society for Photobiology 2012 conference in Montreal, Canada

Presented research at Loyola University symposia; 2011, 2012

Teaching and Mentoring

Mentored undergraduates in research group: Trained students in laboratory safety, synthesis, purification, operation of NMR and UV-Vis instruments, and spectral analysis and interpretation

Taught many college chemistry courses

EDUCATION & CREDENTIALS

Ph.D. Organic Chemistry Synthesis of photosensitizers for use in PDT; Research Director – David Crumrine; Loyola University Chicago (2008-15)

M.S. Analytical Chemistry Governors State University (1988-92); Secondary Science Certification, Governors State University (1984-87)

Internship in Medical Technology MT (ASCP) certified Medical Technologist; St. Francis Hospital School of Medical Technology (1982-83)

B.S. Biology Additional concentration in Chemistry and Mathematics; St. Xavier University (1977-81)

Professional Membership

American Chemical Society (ACS) – 2006 to present

American Society of Clinical Pathologists (ASCP) – 1983 to present

PROFESSIONAL EXPERIENCE

Baxter Healthcare Corporation, Round Lake, IL 6-2017 to 12-2018

Research Associate III (Contractor)

R & D using Low Field NMR spectrometry – tested Baxter solutions of various concentrations; comparison study of spectrometer performance at 270 s and 170 s total acquisition time; prepared solutions, completed notebook summaries, and statistical analyses of data for these projects

Organized spreadsheet data and assisted in a cost analysis involving manufacturing plants to determine feasibility of utilizing Low Field NMR spectrometry to analyze solutions

Document verification of protocols, final reports, risk assessments, and validations, and technical writing of

protocols and final reports for an R & D project to determine trace metal elemental impurities in Baxter products

Verification of filter packs to remove chlorine from a Point of Care Water Device for future use in clinical trials for peritoneal dialysis; analysis of FAPQ fibers used in filter packs via 500 MHz NMR

Stevenson High School, Lincolnshire, IL 9-2016 to 5-2017

Guided Study Teacher

Guided study teacher for Science and Math

Assisted students in completing Chemistry, Biology, Algebra, and Geometry coursework

Substitute Teacher 11-2014 to 8-2016

Substitute taught all levels of Science and Math, as well as other subject areas, as needed

Proctored PARCC, ACT, and PSAT exams; assisted the computer lab with iPad training for Freshman

Loyola University, Chicago, IL 6-2008 to 6-2015

Graduate Student/Teaching Assistant

Developed a folate receptor target-directed Chlorin e6 conjugate that killed 95% of HeLa cells

Synthesized novel small molecule organic compounds for PDT

Mentored many undergraduates in research group

Teaching Assistant: Quantitative Analysis Lab, Organic Chemistry I/II Lab, General Chemistry II Lab, General Chemistry II Discussion sections, weekly Seminar Discussions with Professors from the US and Abroad

Lewis University, Romeoville, IL 6-2006 to 5-2009

Chemistry/Mathematics Professor

Designed websites and curriculum to teach: Analytical Chemistry, Instrumental Analysis, Organic Chemistry I/II, General Chemistry I/II, Math Analysis (precalculus), College Math, Math workshop for nursing students, General Chemistry I/II Lab for AP Chemistry students from Proviso East High School

Triton College, River Grove, IL 8-2002 to 5-2006

Chemistry Professor

Developed websites and curriculum to teach: Organic Chemistry I/II, Elementary Organic Chemistry, General Chemistry I/II, Nursing Chemistry, Chemistry & Society, Chemistry & Society online course

Developed labs for home use by distance online students in the Chemistry & Society course

Moraine Valley Community College, Palos Hills, IL 1-1993 to 12-2003

Chemistry Professor

Created student notes to teach: Fundamentals of Chemistry, General Chemistry I/II

Tutored Chemistry and Mathematics in the Academic Skills Center

Motorola, Inc., Schaumburg, IL 7-1990 to 12-1990

Analytical Laboratory Intern

Method Development using Capillary Electrophoresis to assess resolution of organic acid contaminants in circuit board manufacture; research used to complete thesis for a M.S. in Analytical Chemistry

Moraine Valley Community College, Palos Hills, IL 5-1988 to 6-1989

Educational Coordinator

Employed faculty, scheduled classes, and completed research for program development for continuing educational programs for Allied Health, EMS, and Fire Science personnel

Developed curriculum to teach Coagulation to Medical Laboratory Technology students

Ligo Laboratories, Harvey, IL 6-1985 to 6-1986

Medical Technologist

Operated clinical chemistry, RIA, and hematology instrumentation; Performed phlebotomy

Mercy Hospital, Chicago, IL 6-1984 to 6-1985

Medical Technologist

Operated hematology instrumentation, including calibration and quality control

Completed special staining procedures, sperm counts, phlebotomy

Developed curriculum and taught a Human Anatomy & Basic Pathology course

Hektoen Institute for Medical Research, formerly Cook County Hospital, Chicago, IL 6-1981 to 5-1982

Microbiologist I

Performed diagnostic procedures and ELISA techniques for determination of Rubella,

Rotavirus, and Legionnaires Disease

Prepared stocks of tissue culture and media, and inoculated specimens to test for Chlamydia trachomatis

AFFILIATIONS & HONORS

Awarded a Teaching Scholars Fellowship / Tuition Awards and Student Stipends

Mentored graduate students enrolled in the Teaching Effectiveness Seminars; Planned discussion topics at monthly meetings – 2010-11

Graduate student tuition award – 2014-15; 2013-14; Graduate student stipend – 2012-13; 2009-10

Publications

Design, Synthesis, & Biological Evaluation of Folate Targeted Photosensitizers for Photodynamic Therapy – Ph.D. Dissertation (ProQuest Publishing, 2015)

Synthesis and In Vitro Cell Viability of a Folate Targeted Ce6 Conjugate for Photodynamic Therapy (in press)

Synthesis of Two Phenothiazine Based Photosensitizers for Photodynamic Therapy (in press)

Photodynamic Therapy Review article (in press)

Authored and illustrated Biology for Life, a high school biology text for Seton Home Study School,

Front Royal, VA (2001)

Developed a visual tool for an Algebra II factoring concept and received copyright (2000)

Capillary Electrophoresis Analysis of Two Ion Contaminants of Interest to the Electronics Industry – Master’s Thesis (1993)

Textbook Review

Participated in a focus group to develop a college chemistry text for Benjamin Cummings Publishers, San Francisco, CA (2004)

Reviewed two chapters in a chemistry textbook for McGraw-Hill Publishers (1998)

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