Allison J. Applegate, B.S.

Skin Cancer and Melanoma Biorepository Coordinator 4710 W. 16th Ave

University of Colorado Anschutz Medical Campus Denver, CO 80204

School of Medicine ac1v8i@r.postjobfree.com

Division of Medical Oncology 303-***-****

EDUCATION

University of Colorado, Boulder Boulder, Colorado

Bachelor of Science 2007 - 2011

Speech Language and Hearing Sciences GPA 3.5/4.0

Minor in Linguistics

EXPERIENCE

Clinical/Biorepository Project Coordinator April 2014 - Present

University of Colorado Cancer Center Clinical Trials Office

Developed and coordinated with multiple Principal Investigators for all Biorepository research projects including whole exome sequencing, RNA sequencing, microbiome, and ocular projects.

Recruited patients, obtained consent, gathered materials, and assisted in conducting research for all projects.

Increased subject recruitment by 57% from 2014 to 2016.

Lead a multidisciplinary team of oncologists, surgeons and pathologists in development and communication of research projects to ensure appropriate procedures are completed.

Queried internal database to identify subjects that are appropriate for investigator’s research population.

Prioritized tissue collection modalities (fresh frozen, formalin fixed, or cell line medium) to fit their research needs.

Assisted in the preparation of specimens for study including preparation of serum, DNA extraction from tissues and establishment of cell lines.

Medical record abstraction to ensure each sample appropriate covariate extraction is entered into our internal database.

Assisted a team of Principal Investigators and regulatory affairs personnel to update, revise, and edit the protocol and informed consent form for all patients.

Successfully prepared and passed internal audit without any findings (2015).

Oversaw four protocol amendments from 2014 – Present.

Ensured IRB compliance through reporting, creating SOPs, and implanting GCP.

Well-versed with standard protocols, IFC, CRF language and procedures.

Laboratory liaison with academic institutions/medical companies; oversaw all aspects of collaborations including proposal, budget, requests, and exit interview.

Lead weekly meetings in front of the board including reviewing request for specimens.

Trained over 10 employees within the clinic and laboratory.

Served on both the clinical/laboratory hiring committees.

Specimen Accession Technologist

University of Colorado Dermatopathology Consultants June 2013 – April 2014

Transcribed confidential patient information daily for over 300 dermatology and oral pathology specimens.

Processed customer documents for over 1,314 offices by reviewing data for deficiencies; resolving discrepancies by using standard procedures or returning incomplete documents.

Managed materials for over 50 laboratories across the United States.

Collaborated with IT personnel to improve utility of logging programs; decreased data entry error rate to less than 0.7%

Contributed in the development, implementation and maintenance of Dermatopathology protocols and budgetary goals.

Built on existing customer base by providing the highest level of customer service.

Laboratory Assistant

University of Colorado Dermatopathology Consultants May 2012 – June 2013

Ran histochemical and immunohistochemical staining for over 1,114 offices across the United States.

Protected customer confidentiality by following CAP and HIPPA guidelines.

Handled chemicals, hazardous waste, and sharps.

Special Needs Paraprofessional

Littleton High School August 2011-May 2012

Worked with students with physical and cognitive disabilities.

Implemented team directives concerning instruction, environmental modifications and universal safety precautions within the classroom.

Collaborated with a multidisciplinary team including physical therapists and speech pathologists.

Utilized speech therapy techniques learned from undergraduate degree.

Used curriculum to assist students towards meeting personal and district/state standards.

Implemented the use of adaptive equipment.

PUBLICATIONS

Hintzsche, Jennifer, Kim, J, Applegate, A., et al. "IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples." Journal of the American Medical Informatics Association (2016): 23 (4): 721-730.

Hintzsche, Jennifer D., Gorden, NT, Applegate A.,et al. "Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma." Melanoma Research (2017).

Turner, J., Couts, K., Sheren, J., Saichaemchan, S., Ariyawutyakorn, W., Avolio, I., ... & Applegate, A., et al. (2016). Kinase Gene Fusions in Defined Subsets of Melanoma. Pigment Cell & Melanoma Research.

Smith, Brent J. Jr; Hintzsche, Jennifer D., Applegate, A., et al, (2017) "Systematic Analysis of Whole Exome Sequencing Determines RET G691S Polymorphism as Germline Variant in Melanoma," Marshall Journal of Medicine: Vol. 3: Iss. 2, Article 10.

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