Manager State University
Resume:
Gongbo Wang
Molecular Microbiologist, biochemical assay and in vitro diagnostics product developer with Design of Experiment and Six Sigma skills (proficient user of SAS and Minitab).
**** ***** *lvd Apt 34
Santa Clara, CA 95051
[Do not need work visa or immigration paperwork.]
Cell: 669-***-****
Email: ac0zk9@r.postjobfree.com
PROFESSIONAL EXPERIENCE
Manager of Microbiology R&D
Biomerieux
Shanghai, China 06/2016 – 03/2017
Develop new products: antimicrobial susceptibility, bacterial identification
Conduct competitive studies
Plan and expand R&D capability/facility
Execute collaborative research projects
Associate Director
Innovative Cellular Therapeutics
Shanghai, China 05/2016 – 06/2016
Optimize manufacturing processes of CART product
Research Investigator
Molecular Diagnostics, DuPont Nutrition & Health (USA)
Wilmington, Delaware 12/2014 – 03/2016
Build a new realtime PCR thermo-cycler (X5) into the existing BAX system so that current assays still work on the new hardware and software.
Complete the development stage of a media product to selectively grow Listeria from food and environmental samples based on Six Sigma and Design of Experiment methodologies.
Validate realtime PCR assays detecting bacterial pathogens based on FDA and AOAC regulations.
Research Microbiologist
Molecular Diagnostics, DuPont Nutrition & Health (China)
Shanghai, China 03/2011 – 11/2014
Design and build an R&D P2 lab.
Develop media products to selectively grow certain bacteria using biochemical assays and Design of Experiment tools.
Develop fast methods of detecting bacterial pathogens in food.
Develop realtime PCR chemistry to detect bacterial pathogens in food.
Evaluate candidate PCR platforms for next generation BAX system.
Evaluate and develop DNA extraction/sample preparation methods.
Team/Project Leader
Shanghai Zerun Biotechnology Company (a Wison company),
Shanghai, China 12/2009 – 03/2011
Organize and direct a team of scientists in developing an inactivated vaccine against Enterovirus 71. Finished the early-stage research of product development. Determined the technical details of producing a crude product at lab scale, including cell line, media, cell culture method, infection control, virus harvest method, purification strategy, inactivation scheme and candidate adjuvant.
Post-doctoral Researcher
University of Texas Medical Branch, Galveston, TX 09/2008 – 09/2009
Constructed different versions of Flavivirus Replicon Particles and studied the potential of using these candidates as vaccines against flavivirus infections in mouse models.
Investigated the effectiveness of a JEV vaccine in mouse model in the presence and absence of adjuvants such as IC31® and MF59.
Graduate Research Assistant 08 / 2003 – 08/2008
North Carolina State University, Raleigh, NC
Studied the infection process of Sindbis virus. Used low temperature to inhibit certain cell functions and proved that Sindbis virus is capable of infecting cells in the absence of endocytosis and fusion, revealing a new model for Alphavirus infection.
Studied the importance of transmembrane domains of Sindbis virus on viral structure and assembly. This research uncovered a series of important amino acids in the transmembrane domains of Sindbis virion and provided essential information on vaccine design strategy against Alphavirus infection.
Took applied statistics courses and eventually obtained a degree. In addition to basic statistic theory and concepts, learned and practiced how to design experiment, organize/analyze data, and make conclusions upon analysis result.
EDUCATION
Ph.D., Biochemistry
Ph.D. level full minor, Statistics 08/2003 - 08/2008
North Carolina State University, Raleigh, North Carolina, USA
Field of research: Microbiology, Virology
Research projects: Mechanism of cell infection by Alphaviruses
Structure and assembly of Alphaviruses
Title of dissertation: Sindbis Virus Interaction with Cells
B.S., Genetics 08/1999-06/2003
School of Life Sciences, Fudan University, Shanghai, China
Overall GPA: 3.47 major GPA: 3.51
Dissertation research on yeast genetics
OTHER SKILLS
Design of Experiment
Data analysis on general linear model or mixed model
Time series data analysis
SAS®
Minitab®
Six Sigma Green Belt
JOURNAL PUBLICATIONS
Infection of cells by Sindbis virus at low temperature. Gongbo Wang, Raquel Hernandez, Keith Weninger, Dennis T. Brown (2007) Virology 362(2):461-467
Enhancing the utility of a prM/E chimeric vaccine for Japanese encephalitis by addition of the JEV NS1 gene. Tomohiro Ishikawa, Gongbo Wang, Douglas G. Widman, Ernesto Infante Jr., Evandro Winkelmann, Nigel Bourne, Peter W. Mason.(2011) Vaccine 29(43):7444-7455
Alphavirus Genome Delivery Occurs Directly at the Plasma Membrane in a Time- and Temperature-Dependent Process. Ricardo Vancini, Gongbo Wang, Davis Ferreira, Raquel Hernandez, Dennis T. Brown. (2013) Journal of Virology 87(8):4352-4359
REFERENCES
Dennis Brown (PhD advisor)
ac0zk9@r.postjobfree.com
George Tice (Direct Manager at DuPont, now retired)
ac0zk9@r.postjobfree.com
Jeff Rohrbeck (Direct Manager at DuPont, now Hygiena)
ac0zk9@r.postjobfree.com
Xing Yang (Direct Manager at Biomerieux)
ac0zk9@r.postjobfree.com
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