Sai Charan Penikalapati Bioinformatics Data Analyst

ac04sa@r.postjobfree.com 857-***-**** • Boston, Massachusetts 02120 Dedicated and professional Bioinformatics Analyst with extensive background in Pharmaceutical practices. Seasoned at utilizing talents to investigate and research biologics. Ready to work with teams finding practical purposes for data and developing long lasting solutions. Areas of Expertise include:

Perl SQL BLOSUM

Python Clustal W bowtie2

MS Office

R

BLAST

SAMtools

Mongodb

Professional Experience

Computational Skills

COMPUTATIONAL BIOLOGY

• Query NCBI’s databases using the Entrez query language.

• Perform BLAST sequence alignments utilizing links from Entrez databases.

• Performed Genome Assembly of Rhodobacter using ALLPATHS-LG and SOAPdenovo2.

• Built pipeline for variant calling analysis using Bowtie, Samtools, bcf and vcf tools.

• Performed multiple sequence alignment with Clustal omega and MAFFT.

• Building Phylogenic trees.

PROGRAMMING – R FOR BIOINFORMATICS

• Manipulate data sets within R

• Utilizing Monte Carlos simulations to check various probability properties of random variables.

• Hypothesis testing, creating ANOVA models and conducting analysis in R.

• Working with document databases such as Mongodb and Couchdb.

• Using SQL to store and retrieve data from relational databases Medi Assist India pvt Ltd., Bangalore, India • 2015 to 2016 CLINICAL EXECUTIVE -Validated and approved online health insurance claims for cashless hospitalization using electronic medical records. Internship - Kempegowda Institute of Medical Sciences Hospital & Research Centre • Bangalore, India • 2014 to 2015 CLINICAL PHARMACY INTERN - As part of PHARM-D curriculum reviewed and performed case analysis for treatment. Specialized skills in adverse drug reactions: detection, reporting, monitoring, and documentation. Provided counseling to patients on medication and general health topics. Education & Training

Master’s Degree in Bioinformatics, GPA 3.46

NORTHEASTERN UNIVERSITY Boston, Massachusetts expected, 2018 Molecular Biology Bioinformatics Computational Methods 1 & 2 Bioinformatics Programming Ethics in Biological Research Biostatistics for Bioinformatics Collection Storing & Retrieving Data Doctor of Pharmacy, GPA 3.43

Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka, India, 2015 Research Projects

Polypharmacy and Potentially Inappropriate Medication use in Geriatric Patients, June 2014

• It was a hospital based retrospective study, the main objective of our study was to assess the prevalence of Polypharmacy and inappropriate medication usage in geriatric population. CRISPR Design and Off-Target Analysis, Spring 2016

• Generated CRISPRs from the full Drosophila genome, then the generated CRISPRs were BLASTed against shared BLAST database of Drosophila genome. BLAST hit with 100% identity and alignment length 21 were used for GFF3 entry for that CRISPR. RNASeq, Transcriptome Assembly and Differential Expression Analysis, Fall 2016

• Assembled Transcriptome from RNA Seq illumine reads and identified differential express isoforms utilizing TRINITY pipeline and characterized proteins by blasting against SwissProt database. Designing a SQLite database in R, Spring 2017

• Designed a normalized (3NF) relational data model that has minimal redundancy for airplane bird strikes dataset. Using the design, SQLite database was created and data was retrieved using SQL select statements. Presentations

66th Indian Pharmaceutical Congress, presented a poster on polypharmacy and potentially inappropriate medication use in geriatric patients.

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