Professional Experience Research

Xiao Zhong

** ******* *******, ***.****, Jersey City, NJ, 07310. 765-***-****. *****@***.***

Summary of Core Competencies:

● In-depth understanding of pharmaceutical formulation development

● Knowledge of FDA, USP, and ICH Guidance

● Over ten years of research experience in pharmaceutical, biological, and chemical laboratories

● Strong analytical laboratory skills for pharmaceutical formulation development

● Strong publication record on peer-reviewed journals

● Strong project and time management skills

Selected Research and Professional Experience:

Intern, Evonik, Pharma Polymers, NJ 05/2017-Present

● Developed new formulations for controlled-release solid oral dosage forms using Eudragit ® and Aeroperl ®

● Conducted experiments using Pan Coating, Fluid Bed Coating, and Hot Melt Extrusion

● Conducted analytical tests (Dissolution testing, Disintegration testing, Fiber Optics, SEM, HPLC, GC, FTIR) for controlled-release validation

● Designed protocols for Extrusion Spheronization (ES) using Design of Experiments (DoE) Researcher, Biogen Idec, MA (collaboration through NYU) 03/2014-11/2015

● Investigated crystallization of a protein-based pharmaceutical using X-ray Synchrotron Radiation and Atomic Force Microscopy

● Designed protocols for protein crystallization using Design of Experiments (DoE)

● Worked with a third-party company on screening drug crystallization conditions Researcher, Spheryx, NY (collaboration through NYU) 05/2015-08/2016

● Developed a new technique for monitoring the aggregation of protein-based pharmaceuticals-Holographic Video Microscopy

● Accessed protein-based pharmaceuticals’ shelf-lives Research Associate, New York University, Department of Chemistry, NY 09/2011-04/2017

● Developed crystallization methodologies for the polymorph control of crystalline active pharmaceutical ingredients (APIs)

● Conducted analytical tests (XRD, DSC, TGA, Microscopy) for validation of crystallization outcomes

● Investigated the effect of polymorphism of APIs and excipients on drug formulation and scale-up

● Designed protocols for API polymorphism studies using Design of Experiments (DoE)

● Developed novel polymeric materials for a nanometer-scale resolution printing tool-Polymer Pen Lithography

● Investigated colloidal crystallization mechanisms near confinements fabricated by photolithography via dielectrophoresis

Education:

● Ph.D. Materials Science, New York University, New York, GPA: 3.74 April 2017

● M.S. Biotechnology, New York University, New York, GPA: 3.67 May 2011

● B.S. Biotechnology, Huazhong University of Science and Technology, China June 2009 Publications:

● M. S. D. Wykes, X. Zhong, Y. Liu, T. Adachi, L. Ristroph, M. D. Ward, J. Zhang, M. J. Shelley. Guiding microscale swimmers using teardrop-shaped posts. Soft Matter, 2017, Advance Article.

● X. Zhong, S. S. Lee, M. D. Ward. Electric field-driven nucleation of colloids in the presence of confinements. Langmuir In Preparation.

● X. Zhong, Y. Sun, C. Kang, G. Wan. The theory of dielectrophoresis and its applications on medical and materials. Eur. J. BioMed. Res. 2 (4), 2017, 2 (4), 7-11.

● C. Wang, F. C. Cheong, D. B. Ruffner, X. Zhong, M. D. Ward, D. G. Grier. Holographic characterization of colloidal fractal aggregates. Soft Matter 2016, 12 (20), 8774-8780.

● M. S. D. Wykes, X Zhong, Y. Liu, T. Adachi, L. Ristroph, M. D. Ward, J. Zhang, M. J. Shelley. Steering artificial micro-scale swimmers using teardrop-shaped posts. Bull. Am. Phys. Soc., 61. 2016.

● C. Wang, X. Zhong, D. B. Ruffner, A. Stutt, L. A. Phillips, M. D. Ward, D. G. Grier. Holographic characterization of protein aggregates. J. Pharm. Sci., 2016, 105(3), 1074- 1085.

● Y. Sun, C. Kang, A. Zhang, F. Liu, J. Hu, X. Zhong, J. Xie. Co-delivery of dual-drugs with nanoparticle to Xiao Zhong

overcome multidrug resistance. Eur. J. BioMed. Res. 2016, 2 (2), 12-18.

● M. S. D. Wykes, J. Palacci, T. Adachi, L. Ristroph, X. Zhong, M. D. Ward, J. Zhang, M. J. Shelley. Dynamic self-assembly of microscale rotors and swimmers. Soft Matter 2016, 12 (20), 4584-4589.

● Y Sun, X. Zhong, C. Kang, Nanomedicine for Treatment of Cancer, Pharm. Sci. Tech. 2016, 1(2), 4-5.

● T. Mandal, A. G. Shtukenberg, A. C. Yu, X. Zhong, M. D. Ward, Effect of Urinary Macromolecules on l- Cystine Crystal Growth and Crystal Surface Adhesion. Cryst. Growth Des. 2015, 16 (1), 423-431.

● S. S. Lee, K. A. Collins, X. Zhong, P. Song, N. R. Little, M. D. Ward. Electric-Field-Induced Reversible Phase Transitions in Two-Dimensional Colloidal Crystals. Langmuir, 2015, 31, 10411.

● X. Zhong, N. A. Bailey, K. B. Schesing, S. Bian, L. M. Campos, A. B. Braunschweig, Materials for the preparation of polymer pen lithography tip arrays and a comparison of their printing properties. J. Polym. Sci. A Polym. Chem. 2013, 51, 1533. Journal Cover.

● B. Guo, X. Zhong, Asarone treatment of children with bonchiolitis, J. Jilin Med. 2008, Dec.2215-2216.

● T. Li, X. Zhong, Amoxicillin tablets preparation and the study of its nature, J. Jilin Med. 2008, Dec. 2158- 2160.

● G. Liu, X. Zhong, The clinical observation of Shenyi capsule combined chemotherapy for adjuvant treatment of lung cancer after operation, J. Jilin Med. 2008, Nov.1905-1906.

● X. Zhong, Research progress of lysosome, Chin. J. Biols, 2008, Sept.827-829.

● B. Guo, Z. Li, X. Zhong, Statistical analysis of clinical use of anti-infectives, Chin. Comm. Docs, 2008, 23-24. Granted Patent:

● A. B. Braunschweig, X. Zhong, K. B. Schesing, S. Bian, “Polymer Tips” Non-Provisional Patent US2014/0141167 A1.

Journal Editorial Board member:

● Journal of Photonic Materials and Technology

● Pharmaceutical Sciences and Technology

Peer-review Service Journals:

● Journal of Polymer Science Part A: Polymer Chemistry

● Journal of Colloid and Interface Science

● Journal of Materials Engineering and Performance

● International Journal of Polymer Science

● Journal of Experimental Nanoscience

● Journal of Nano Research

● Journal of Visualized Experiments

● Journal of Composite Materials

● Academic Research Journal of Biotechnology

Selected Presentations:

● Oral presentation, Crystal polymorph and orientation control in corrals created by Polymer Pen Lithography” Gordon Research Seminar, Thin Film & Crystal Growth Mechanisms, July 6-7, 2013, University of New England.

● Poster presentation, X. Zhong, S. S. Lee, M. D. Ward. 88th ACS Colloid & Surface Science Symposium, June 22-25, 2014, University of Pennsylvania.

● Poster presentation, X. Zhong, M. D. Ward. 2014 Journey Through Science Day hosted by the PepsiCo and the New York Academy of Sciences, December 8, 2014, The New York Academy of Sciences. Languages:

● Fluent in English and Mandarin

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