Quality Control Assistant

Disha Sahetya

Address: **** ******** **, *** **, Boston, MA 02215

Phone: 617-***-**** E-mail: *****.*******@*****.***

I am looking for an opportunity, where I can utilize my pharmacological understanding of drug action and apply it to clinical studies, giving me valuable experience and helping me establish a foundation for a career in clinical research.

EDUCATION

Northeastern University, Boston, MA, Masters in Pharmacology (GPA 3.5) September 2011-May 2013

Ø Relevant Coursework: Biochemistry, Molecular cell biology, Pharmacology, Receptor Pharmacology, Concepts in Pharmaceutical Science, Research Skill and Ethics, Clinical Psychopharmacology, Experimental Design and Biometrics, Enterprise growth and Innovation, Pharmaceutical Science Laboratory.

Mumbai University, Mumbai, India, Bachelor of Pharmacy (GPA 3.74) August 2007-June 2011

Ø Relevant Coursework: Pharmaceutical Chemistry, Microbiology, Pharmacology, Pharmaceutics, Biotechnology,Anatomy, Physiology, Medicinal Chemistry and Pharmaceutical Analysis. Laboratory work in all the above subjects.

SKILLS

Clinical reasoning, Drug Safety and Interactions, GCP, IRB guidelines and FDA regulations.

Data analysis and presentation: Microsoft Office, ImageJ, SPSS (t-tests, one way, two way and RM ANOVA’s), Etholog for recording changes in behavior after drug administration and Graphpad Prism.

Basic Molecular Biology skills: Aseptic technique, cell culture techniques, western blotting, ELISA, PCR, plasmid preparation, protein purification, DNA/RNA isolation and quantification, immunofluorescence technique, Affinity chromatography, Thin

Layer Chromatography, SDS Page and gel electrophoresis.

Animal handling skills: Basic rodent handling skills, I.P, S.C injection techniques, temperature probing, tail dip and tail flick

studies, oral gavage and rat training for operant studies.

Pharmacokinetic evaluation: Evaluation of Pharmacokinetic parameters using plasma samples, Enzyme kinetics, Biochemical

assays, dissolution and disintegration testing for normal and sustained release tablets and capsules.

PROFESSIONAL EXPERIENCE

Center for Drug Discovery, Northeastern University, Boston, MA July 2012-March 2013

Laboratory Assistant

Responsibilities: Intra-Peritoneal injections in rats and drug discrimination studies to determine addictive potential of certain cannabinoid drugs.

Behavioral Pharmacology Laboratory, Northeastern University, Boston, MA November 2011-December 2012

Research Assistant

Responsibilities: Basic weighing, temperature probing and tagging of rats and mice. Assisting in training rats for operant studies using alcohol self administration technique, testing analgesic effects of opioids and alcohol using tail dip and tail flick studies in

mice. Assisting in dissection and organ removal for binding studies.

Conducted two independent research studies on metabolic and diuretic effects of cannabinoid compounds:

January’13- April’13: Study co-relating the differences in weight, fluid loss and food intake after daily Sub-Cutaneous dosing of rats with THC and other synthetic cannabinoid analogs.

August’13- December’ 13: Study analyzing diuretic effects of synthetic cannabinoids in rats by analyzing concentration of Na, K,Cl and pH changes in urine at specific time intervals after dosing. Result of the study indicated no net loss of electrolytes but increase in volume of fluid lost after drug administration.

Aurochem Laboratories, Pvt Ltd, Maharashtra, India Jun-Aug 2010

Quality Control (Intern)

Introduced to formulation techniques for tablets, capsules and topical dosage forms.

Quality control tests for raw materials and final products.

OTHER EXPERIENCE

NIH online certificate course in Clinical Research April, 2013

Understanding basic principles underlying clinical research, FDA regulations, IRB and ICH guidelines pertaining to clinical studies, Stages of Clinical Trials and roles and responsibilities of a Principal Investigator and the team conducting a trial.

NU Science and Engineering Club, Northeastern University, Boston, MA January 2012-August 2012

Attended the certified Mini- MBA series of lectures and participated in the club’s weekly activities and seminars.

Center for Research Innovation, Northeastern University, Boston, MA February 2012-April 2012

Formulated a marketing plan for the commercialization of a patented diagnostic technology aimed at diagnosis of schizophrenia at early stages using detection of low levels of phospholipid methylation in D4 receptors in lymphocytes .

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