Project Data

xiao zhang

Email: *********@********.***

Address: *** ********** ****

City: Rochester

State: NY

Zip: 14620

Country: USA

Phone: 585-***-****

Skill Level: Assistant

Salary Range: $70,000

Willing to Relocate

Primary Skills/Experience:

See Resume

Educational Background:

See Resume

Job History / Details:

Xiao Zhang, PhD

University of Rochester 585-***-**** **************@*****.***

PROFESSIONAL HIGHLIGHTS

Extensive experience with data analysis and statistical modeling techniques, including ANOVA, MANOVA, linear mixed model, generalized linear model (GLM), generalized estimating equations (GEE), weighted estimating equations (WEE), multiple imputation, proportional hazards model, Poisson regression model, Survey-weighted-regression model

Over five (5) years of consulting experience in SAS programming for clinical trial data analysis; expertise in creating, coordinating and analyzing clinical trial data, generating reports, tables, listings and graphs, using SAS/BASE, SAS/MACROS, SAS/STAT, SAS/GRAPH, SAS/SQL, SAS/ODS

Extensive knowledge of statistical methods and proficient in statistical procedures in SAS to perform statistical analysis, including PROC GLM, PROC ANOVA, PROC MIXED, PROC TTEST, PROC GENMOD, PROC LOGISTIC, PROC GLMMIX, PROC PHREG, PROC LIFEREG, PROC MI, PROC MIANALYZE, etc.

Extensive research interests including group sequential design, clinical experimental design, longitudinal study, survival analysis, Bayesian methodology, ROC-curve methodology, mode estimation, and multiple testing

Substantial experience in collaboration with investigators for a variety of projects on neural development, oral biology, heart research, and pulmonary and critical care medicine etc.

WORKING EXPERIENCE

Research Assistant at University of Rochester Jun 2008 present

Research project 1: Multicenter Automatic Defibrillator Implantation-Trial Cardiac Resynchronization Therapy (MADIT-CRT) study: The worlds largest randomized Class I/II cardiac resynchronization device trial

Worked with Dr. Moss group in Heart Research Follow-up Program. This study is sponsored exclusively by Boston Scientific. This trial demonstrated that early intervention with cardiac resynchronization therapy can slow down the progression of heart failure

Assessed the CRT-D vs. defibrillator-only risk for non- fatal first- and for subsequent-heart failure events (HFEs) by Kaplan-Meier curves, Cox proportional-hazards modeling, and Andersen-Gill proportional-intensity regression modeling in efficacy analyses

Research project 2: Detecting Axonal Damage after Mild Traumatic Brain Injury (TBI)

Worked with Dr. Bazarians group from the Center for Neural Development and Disease, detected clinically important axonal damage in cerebral white matter after mild TBI using diffusion tensor imaging (DTI)

Computed Westfall &Youngs permutation-based step-down adjusted p-values, rigorously adjusting for multiple Mann-Whitney-Wilcoxon tests

Research project 3: GTFB/caries preliminary biomarker study

Worked with Dr. Bowens group from Center for Oral Biology, analyzed the data include a biomarker (GTFB) obtained from the saliva of children with Early Childhood.

Fit marginal logistic models for specificity and sensitivity of GTFB as a diagnostic biomarker for caries development as functions of time using GEE

Statistical Consultant at University of Rochester Medical Center Sep 2009 present

Duties include statistical consultation on the design and analysis of scientific experiments across a variety of disciplines for medical doctors and other health professionals

Research Project: Mary Parks Asthma Registry

Worked with Pulmonary and Critical Care Medicine Group, used non-invasive biomarkers to monitor airway inflammation in subjects with varying degrees of asthma

Used SAS to conduct logistic regression and fit a GEE model for repeated measures data and used the Johnson-Neyman technique to find the simultaneous regions of significance for each subject group.

Data Analyst at Dalian East Market Research Co. Ltd, CHINA Jul 2004 Jul 2005

Participated in collecting, analyzing, translating and updating market data using Excel and SPSS

Instructor at University of Rochester Jun 2012

Taught Introduction to Statistical Software: R

RESEARCH EXPERIENCE

Hypothesis Testing Problems Involving Order Constrained Parameters (advisor: Dr. Michael McDermott)

Developed the Elliptical Likelihood Ratio Test (ELRT) for the null hypothesis that a mean vector is equal to zero against an alternative that is constrained to lie in an elliptical cone

Explored some new methods for combining dependent p-values and investigated their utility when applied to the problem of testing equality of ordered means

Developed and evaluated likelihood ratio tests and tests based on statistics for combining independent p-values for the null hypothesis of equality of ordered modes from Co-Gaussian distributions

Group Sequential Data Analysis study (advisor: Dr. W. Jackson Hall)

Reviewed methods for group sequential analysis with applications to clinical trials and conducted analyses on a real data set using an experimental package in SAS 9.2

Assisted Dr. W. J. Hall with data analysis and plots for his chapter Analysis of Sequential Clinical Trials for the book Modern Clinical Trial Analysis, edited by W. Tang and X. M. Tu, Springer, New York, 2012

Sample Size Estimation in Capture-recapture Problem (advisor: Dr. Govind Mudholkar)

Developed a new Wilson confidence interval for the population size in a capture-recapture problem and compared it with classical confidence intervals

Also applied Bayesian methods on the estimation of population size in a capture-recapture problem

SKILLS

Specialties: SAS (BASE/STAT/SQL/MACRO/GRAPH), Excel (VBA/Macro/Package/Function/Pivot Table), R/S-Plus

Other Programming Languages: Matlab, Maple, Mathematica, C++, SPSS, MINITAB, Stata, LaTeX

EDUCATION

PhD Candidate in Statistics, University of Rochester, Rochester, NY December 2013

M.S in Statistics, East Tennessee State University, Johnson City, TN July 2007

M.S. in Applied Mathematics, Jilin University, Changchun, China July 2004

B.S. in Applied Mathematics, Jilin University, Changchun, China July 2002

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