Supervisor Manager

Curriculum Vitae of

P.O. Box ***

Midway, TX **852-0158

Phone: 979-***-****

E-mail: ****@******.***

Web: http://www.ovitra.com

Brad R. Lindsey,

Ph.D.

Education

Sep.

**** ***. ****. **iversity of Nebraska,

Lincoln, NE

Ph.D.

/ Animal Science / Physiology / Reproductive Endocrinology / Advisor: Dr. Jim

Kinder

Dissertation: "Exogenous

Hormonal Control of Gonadotropin Release Affecting Dominant, Persistent, and

Superstimulated Ovarian Follicle Development in Cattle"

May

1982 - Dec. 1984. TexasA&MUniversity, College Station, TX

M.Agr.

/ Animal Science / Equine Reproduction / Advisor: Dr. Jack Kreider

Thesis: "Recipient

mare management for commercialized embryo transfer"

Aug.

1978 May 1982. TexasA&MUniversity, College Station, TX

B.S.

/ Agricultural Economics / Agribusiness

Professional Experience

Aug. 2005 Present. Founder

/ CEO, Ovitra Biotechnology, Inc. (formerly Rex Consulting) Midway, TX

Sep. 2004 Jul.2005. General

Manager, Female Reproductive Services. Genetic Resources Int l / Navasota, TX

/ Supervisor: Juan Moreno, Owner/CEO

Jul. 2002 Aug. 2004.

Director of Bovine Biotech

Product Development. Minitube of AmericaVerona, WI / Supervisor: Ludwig Simmet, Owner/CEO

Mar.

2000 Jun. 2002. Senior Scientist, Research &

Development. AB Technology, Inc. / Pullman,

WA / Supervisor: Trevor Steel,

CEO

Jun.

1998 Mar. 2000. General Manager. Stroud Veterinary Embryo Services / Weatherford, TX

/ Supervisor: Brad K. Stroud, DVM, Owner

Sep. 1997 - Mar. 1998. Research Associate. Tropical Beef Centre / Rockhampton, Queensland,

Australia /

Supervisor: Michael D Occhio, PhD, Professor

May

1995 Aug. 1997. Research Technician II. University of Nebraska

/ Animal Science Dept. / Lincoln,

NE / Supervisor: Jim Kinder,

PhD, Professor

Jan.

1992 - Aug. 1994. Director - IVF Services. Trans Ova Genetics / Sioux Center, IA

/ Supervisor: Dave Faber, DVM, Owner/CEO

Sep.

1988 Dec. 1991. Production Laboratory Supervisor /

Embryologist. Granada

BioSciences / Genetics Div. / Marquez,

TX / Supervisors: Mike Wilson,

PhD, GM / Joe Oden, DVM, GM

Dec.

1983 - Aug. 1988. Reproductive

Physiologist. Granada

Equine Services / Reproductive Lab / Wheelock,

TX / Supervisor: Steve

Vogelsang, MS, GM

Professional Affiliations, & Committees

International

Embryo Transfer Society (member)

Research

& Technology Sub-Committee of Companion Animal, Non-Domestic, &

Endangered Species Committee

Local

Organizing Committee Chairman for Portland 2004 Annual Meeting

American

Embryo Transfer Association (member)

Chairman,

Newsletter Committee

Member,

Certification Committee

Adjunct

Professor, Dept. of An. Sci. WSU-Pullman, WA / 2000-2002

Adjunct

Professor, Dept. of An. Sci. UW-Madison, WI / 2002-2004

Invited Presentations

Oct. 2008 / Speaker / AETA

Pre-Conference Seminar / Topic: Emerging

TechnologiesKansas City,

Missouri, USA

Nov. 2006 / Speaker / PBR Finals /

Topic: Reproductive Technologies for

Bucking StockLas Vegas,

Nevada, USA

Aug. 2003 / Speaker / AETS Main

Program / Topic: Improving Embryo

Media Quality and MicroenvironmentBrisbane, Queensland, Australia

Oct. 2002 / Speaker / AETA Main

Program / Topic: Recent Advancements

in Embryo Media and Related TechnologiesAlbuquerque, NM, USA

Sep. 2002 / Speaker / AABP Pre-Conference Seminar /

Topic: Embryo Media and Applied

Research StrategiesMadison,

WI, USA

Aug. 2002 / Speaker, Panelist / CETA / Topic: Applied Embryo Research StrategiesQuebec City, Quebec,

Canada

Jun. 2001 / Speaker / CRB Annual Retreat / Topic: Exogenous Control of Gonadotropin Release

During Ovarian Superstimulation in CattleCouer d Alene Lake, ID,

USA

Sep. 2000 / Instructor / AABP Pre-Conference Seminar /

Topic: Embryo Micro-manipulation &

Gender DeterminationRapid

City, SD, USA

Aug. 1999 / Speaker / CETA Main Program / Topics: The

Role of FSH and LH in Ovarian Follicular Development in Cattle and A GnRH Agonist Model for Superovulation

in CattleLondon, Ontario, Canada

Oct. 1998 / Speaker / AETA Main Program / Topic: GnRH Agonist Model for SuperovulationSan Antonio, TX, USA

Aug. 1996 / Instructor / Partners

of the Americas / Federal University of Piaui

/ Seminar & Workshop: Bovine ET

MethodologyTeresina, Piaui, Brazil

Jan. 1994 / Panelist / IETS Annual

Meeting / Topic: Commercial Bovine IVF

Techniques Melbourne,

Victoria, Australia

Jan. 1992 / Instructor / IETS Annual

Meeting / Workshop: Oocyte Retrieval

Procedures / CSU Foothills Campus, Ft. Collins, CO, USA

Publications

Vogelsang,

M.M., S.G. Vogelsang, B.R. Lindsey

and J.M. Massey. 1989. Reproductive performance of mares subjected to

routine examination by diagnostic ultrasound. Theriogenology 32:95-103.

Looney, C.R., B.R.

Lindsey, C.L. Gonseth and D.L. Johnson. 1994. Commercial aspects of

oocyte retrieval and in vitro

fertilization (IVF) for embryo production in problem cows. Theriogenology

41:67-72.

Splan, R.K., B.R. Pilcik, U.J. Tomsen, J.A.G. Arango, A.

Ruiz-Flores, J.W. Hallock, M.F. Allan, S.K.R. Karnati, V. Vega, B.R. Lindsey, D.E. Moody and D. Pomp.

1998. Rapid Communication: Mapping of the steroidogenic

acute regulatory protein (StAR) gene to porcine chromosome 15 by linkage

analysis using a novel PCR-RFLP. J. Anim. Sci. 76:658-659.

Melvin, E.J., B.R.

Lindsey, J. Quintal-Franco, E. Zanella, K.E. Fike, C.P. VanTassell, and

J.E. Kinder. 1999. Circulating concentrations of estradiol, luteinizing

hormone, and follicle stimulating hormone during waves of ovarian follicular

development in prepubertal cattle. Biol. Reprod. 60:405-412.

Fike, K.E., M.E.

Wehrman, B.R. Lindsey, E.G. Bergfeld, E.J. Melvin, J.A. Quintal, E.L.

Zanella, F.N. Kojima, and J.E. Kinder. 1999. Estrus synchronization of beef

cattle with a combination of melengestrol acetate and an injection of

progesterone and 17beta-estradiol. J Anim Sci 77:715-723.

D Occhio, M.J., D. Jillella and B.R.

Lindsey. 1999. Factors that influence follicle recruitment, growth and

ovulation during ovarian superstimulation in heifers: opportunities to

increase ovulation rate and embryo recovery by delaying the exposure of

follicles to LH. Theriogenology 51:9-35 (Review).

Quintal-Franco, J.A., F.N.

Kojima, E.J. Melvin, B.R. Lindsey,

E. Zanella, K.E. Fike, M.E. Wehrman, D.T. Clopton and J.E. Kinder. 1999.

Corpus luteum development and function in cattle with episodic release of

luteinizing hormone pulses inhibited in the follicular and early luteal

phases of the estrous cycle. Biol Reprod. 61:921-926.

Rorie, R.W., T.D. Lester, B.R. Lindsey, and R.W. McNew. 1999. Effect of timing of artificial

insemination on gender ratio in beef cattle. Theriogenology 52:1035-1041.

Hammer, C.J., H.D.

Tyler, L.M. Loskutoff, D.L. Armstrong, D.J. Funk, B.R. Lindsey, and

L.G. Simmons. 2001. Compromised development of calves (Bos gaurus) derived

from in vitro-generated embryos and transferred interspecifically into

domestic cattle (Bos taurus).

Theriogenology 55(7):1447-55.

Lindsey, B.R., L.J. Maclellan, T.R.

Whyte, J.E. Kinder and M.J. D'Occhio. 2002.

Differential requirement for pulsatile LH during the follicular phase

and exposure to the preovulatory LH surge for oocyte fertilization and embryo

development in cattle. Theriogenology 58(9):1651-1662.

Lindsey, B.R.,

K.E. Fike, J.A. Quintal, E.L. Zanella, J.W. Koch, L.R. Ehnis, and J.E.

Kinder. Antagonist of gonadotropin hormone-releasing hormone suppression of

follicle stimulating hormone (FSH) is dependent on concentration of FSH at

time of administration in cattle. Biol. Reprod. (in-progress).

Lindsey, B.R.,

M.E. Wehrman, E.J. Melvin, J.A. Quintal, F.N. Kojima, E.L. Zanella, K.E.

Fike, E.G.M. Bergfeld, and J.E. Kinder. Ovarian follicular growth and

endocrine responses following a single injection of progesterone in cows

(in-progress).

Lindsey, B.R.,

M.E. Wehrman, E.J. Melvin, J.A. Quintal, F.N. Kojima, E.L. Zanella, K.E.

Fike, E.G.M. Bergfeld, and J.E. Kinder. Effects of increased duration of

endogenous LH pulses during superovulation in cattle on circulating hormones,

ovarian follicular growth, intrafollicular steroids, oocyte maturation and

embryo development (in-progress).

Lindsey, B.R.,

M.E. Wehrman, J.A. Quintal, E.J. Melvin, E.L. Zanella, K.E. Fike, F.N.

Kojima, and J.E. Kinder. Effect of duration of exposure to low LH pulse

frequencies on development and biochemical characteristics of persistent

ovarian follicles and on circulating hormones in beef cows (in-progress).

Symposia / Proceedings / Abstracts

Lindsey, B.R.,

C.R. Looney, D.J. Funk, D.C. Faber, C.S. Gue and A.J. Kramer. 1994. The

effect of apparent dominant follicle removal (DFR) prior to FSH treatment on

superstimulated response. Proceedings IETS Annual Meeting. Theriogenology 41(1):238.

Armstrong, D.L., C.R. Looney, B.R. Lindsey, C.L. Gonseth, D.L. Johnson, K.R. Williams, L.G.

Simmons and N.M. Loskutoff. 1995. Transvaginal egg retrieval and in vitro embryo production in guar

(Bos guarus) with establishment of interspecies pregnancy. Proceedings IETS

Annual Meeting. Theriogenology 43(1):162.

Looney, C.R., P. Damiani, B.R. Lindsey, C.R. Long, C.L. Gonseth, D.L. Johnson, and R.T.

Duby. 1995. Use of prepuberal heifers as oocyte donors for IVF: Effect of age

and gonadotropin treatment. Proceedings IETS Annual Meeting. Theriogenology

43(1):267.

Paul, J.B., C.R. Looney, B.R. Lindsey and R.A. Godke. 1995. Gonadotropin stimulation of

cattle donors at estrus for transvaginal oocyte collection. Proceedings IETS

Annual Meeting. Theriogenology 43(1):295.

Lindsey, B.R.,

M.E. Wehrman, E.J. Melvin, J.A. Quintal, F.N. Kojima, E.L. Zanella, K.E.

Fike, E.G.M. Bergfeld, and J.E. Kinder. 1995. Ovarian follicular growth and FSH

secretion following a timed injection of progesterone in cows. Proceedings

IETS Annual Meeting. Theriogenology 45(1):328.

Melvin, E.J., B.R.

Lindsey, J.A. Quintal-Franco, E. Zanella, C.P. VanTassell, K.E. Fike, and

J.E. Kinder. 1996. Patterns of ovarian follicular growth following follicle

ablation in heifers form eight to one month prepuberty. Proceedings SSR

Annual Meeting. Biol. Reprod. 54:178.

Fike, K.E., M.E. Wehrman, B.R. Lindsey, E.G. Bergfeld, E.J. Melvin, J.A. Quintal, E.L.

Zanella, and J.E. Kinder. 1997. Estrous synchronization in beef cattle with

melengesterol acetate (MGA) and an injection of progesterone (P4).

Proceedings ASAS Annual Meeting. J. An. Sci. 75:232.

Jimenez-Severiano, H., J. Quintal-Franco, V.

Vega-Murillo, E. Zanella, M.E. Wehrman, B.R.

Lindsey, E.J. Melvin and J.E. Kinder. 1997. Response of testis of bulls

to LH during different seasons of the year. Proceedings SSR Annual Meeting.

Biol. Reprod. 56:112.

Fike, K.E., F.N. Kojima, E.G. Bergfeld, B.R. Lindsey, E.J. Melvin, J.A. Quintal,

E.L. Zanella, M.E. Wehrman, and J.E. Kinder. 1997.

Magnitude of shift in concentration of progesterone (P4) in

circulation does not alter LH secretion to the same extent as absolute

concentrations of P4 in heifers. Proceedings SSR Annual Meeting.

Biol. Reprod. 56:120.

Lindsey, B.R.,

M.E. Wehrman, E.J. Melvin, J.A. Quintal, F.N. Kojima, E.L. Zanella, K.E.

Fike, E.G.M. Bergfeld, and J.E. Kinder. 1997. Circulating progesterone and

intrafollicular steroid concentrations in dominant ovarian follicles following

an injection of progesterone in cows. Proceedings ASAS Annual Meeting. J. An.

Sci. 75: 227.

Lindsey, B.R.,

K.E. Fike, J.A. Quintal, E.L. Zanella, J.W. Koch, L.R. Ehnis, and J.E.

Kinder. 1997. Effects of LHRH antagonist and bFF on FSH secretion and ovarian

follicle development in heifers. Proceedings SSR Annual Meeting. Biol.

Reprod. 56:120.

Fischer-Brown

AE, Lindsey BR, Ireland

FA, Northey DL, Monson RL, Clark SG, Wheeler

MB, Kesler DJ, Lane SJ, Weigel KA, Rutledge JJ. 2005. Embryonic disc

development and subsequent viability of cattle embryos following culture in

two media under two oxygen concentrations. Reprod. Fertil. Dev. Jan. 13;

16(8):787-793.

Ehnis, L.R., J.W. Koch, B.R. Lindsey, H. Jimenez-Severiano, V.E. Vega-Murillo, H.D. Hafs,

and J.E. Kinder. 1998. Efficacy of intravaginal progesterone releasing insert

to advance date of estrus and synchronize estrus in post-partum beef cows and

peripubertal heifers. Proceedings ASAS Midwest

Section Meeting. #167.

Ehnis, L.R., J.W. Koch, B.R. Lindsey, H. Jimenez-Severiano, V.E. Vega-Murillo, H.D. Hafs, and J.E. Kinder. 1998. Estrous

and ovulation suppression and corpus luteum (CL) function in cows treated

with a progesterone releasing intravaginal insert. Proceedings ASAS Midwest Section Meeting. # 166.

Lindsey, B.R. 1998.

A GnRH agonist model for superovulation in cattle. Proceedings AETA Annual

Meeting, 64-74.

Clopton, D.T., B.R.

Lindsey, A. Clark, A. Klein, and J.E. Kinder. 1999. Duration of treatment

with short-term, large doses of progesterone regulates luteinizing hormone

receptor and aromatase mRNA content and steroid ratio in persistent ovarian

follicles. Proceedings SSR Annual

Meeting XX:XXX.

Echternkamp, S.E., K.E. Gregory, B.R. Lindsey, M. Mussard, J.E. Kinder. 1999. Comparison of FSH and LH response to

follicle aspiration in cattle selected (twinner) and unselected (control) for

twin births. Proceedings SSR Annual Meeting XX:XXX.

Lindsey, B.R. and

J.E. Kinder.1999. The role of

follicle stimulating hormone and luteinizing hormone in ovarian follicular

development in cattle. Proceedings CETA / ACTE Annual Meeting, 4.

Lindsey, B.R. and

M. D Occhio.1999. A GnRH model

for superovulation in cattle. Proceedings CETA / ACTE Annual Meeting, 5.

Rorie, R.W., T.D.

Lester, B.R. Lindsey, and R.W.

McNew. 1999. Effect of timing of insemination on sex ratio in beef cattle.

Proceedings IETS Annual Meeting. Theriogenology 51(1):399.

Loskutoff, N.M., D.L. Armstrong, C.L. Ohlrichs, D.L.

Johnson, D.J. Funk, P.V. VanRoekel, J.A. Molina, B.R. Lindsey, C.R. Looney, and L.G. Simmons. 2000. Transvaginal,

ultrasound-guided oocyte retrieval and the developmental competence of in

vitro produced embryos in vitro and in vivo in the Guar (Bos guarus).

Proceedings IETS Annual Meeting.

Theriogenology 53(1):337.

Bader, J.F., F.N. Kojima,

M.E. Wehrman, B.R. Lindsey, M.S. Kerley, and D.J.

Patterson. 2002. Effects of prepartum lipid supplementation of FSH

superstimulation and embryo quality in multiparous beef cows. Proceedings

IETS Annual Meeting. Theriogenology 57(1):760.

Kojima, F.N., J.F. Bader, B.R. Lindsey, M.E. Wehrman, W.L. Malcolm, J.E. Stenger, and D.J.

Patterson. 2002. Evaluation of an estrus synchronization protocol prior to

superovulation in beef cows. Proceedings IETS Annual Meeting. Theriogenology

57(1):766.

Rozeboom, K.J., B.R.

Lindsey, and M.E. Wilson.

2003. Effect of semen extender on oocyte penetration capacity by porcine

spermatozoa in vitro. Proceedings

IETS Annual Meeting. Theriogenology 59(1):229.

Lindsey, B.R.,

S. Schlee, and S. Terlouw. 2003. Embryo media: quality control analysis and

biocompatibility testing. Embryo Transfer Newsletter of the IETS 21 (2):4-11.

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