Medical Computer Science

A. A Martinos Center; MGH Email: *******@***.***.*******.***

*** **** ******; Room 2301 Phone: 617-***-****

Charlestown, MA 02139 Fax: 617-***-****

Lilla Z llei

Research-oriented academic position in the field of medical image analysis. Preference given to

Objective

statistical and information theoretic approaches.

2001-2006 Massachusetts Institute of Technology Cambridge, MA

Education

Ph.D., Electrical Engineering and Computer Science

Thesis: Unified Information Theoretic Framework for Pair- and Group-wise Registration of

Medical Images

Advisors: Prof E. Grimson, Prof W.M. Wells

1999-2001 Massachusetts Institute of Technology Cambridge, MA

MS., Electrical Engineering and Computer Science

Thesis: 2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images

Advisors: Prof E. Grimson, Prof W.M. Wells

1995-1999 Mount Holyoke College South Hadley, MA

BA., Computer Science and Mathematics (summa cum laude)

Thesis: Place Recognition Using Color Region Analysis

Advisors: Prof C. Fennema

Work and Research 2010 present Massachusetts General Hospital Charlestown, MA

Experience

Instructor: Finding mathematical correspondence between various types of MRI acquisitions

of the developing brain, designing automatic segmentation tools and analyzing diffusion

weighted images.

2006 2010 Massachusetts General Hospital Charlestown, MA

Research Fellow: Finding mathematical correspondence between various types of MRI

acquisitions of the brain; statistical comparison of control and diseased groups.

2005 2006 Ecole Centrale de Paris Paris, France

Postdoctoral Researcher and Lecturer: Analyzed Diffusion Tensor MRI images of skeletal

muscle. Designed and taught introductory image processing class (Image Processing: Basics,

Lilla Z llei (2/5)

Challenges and Perspectives)

1999 2005 Massachusetts Institute of Technology Cambridge, MA

Research and Teaching Assistant: Investigated 2D/3D and 3D/3D correspondence of MRI,

CT and fluoroscopy images. Lectured and assisted in the graduate level biomedical image

processing class (Biomedical Signal and Image Processing).

Summer 2002 Project Odyssee, INRIA Sophia Antipolis, France

Visiting Researcher: Identified effects of physiological noise in functional MRI.

Summer 2000 Visualization Technology, Inc Lawrence, MA

Software Consultant: Integrated a 3D-3D CT-MRI rigid body alignment algorithm into a

commercial software package.

Summer 1999 Small Business Group, Microsoft, Co Redmond, WA

Software Design Engineer: Designed and tested modules for initiating outgoing and monitoring

incoming phone calls in Outlook.

Summer 1998 GTE Laboratories Waltham, MA

Software Developer: Helped designing a Web-based telecommunications ordering system.

Age-Dependent Analysis Techniques for Pediatric Structural and Diffusion MRI Data (NIH

Grants

Pathway to Independence (PI) Award (K99/R00)); July 1, 2010 - present

L. Z llei: 2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images, MS Thesis,

Publications

AI Lab, MIT, August 2001.

L. Z llei, et al.: 2D-3D Rigid Registration of X-Ray Fluoroscopy and CT Images Using

Mutual Information and Sparsely Sampled Histogram Estimators, IEEE CVPR, 2001.

A. Yezzi, L. Z llei, et al.: A Variational Framework for Joint Segmentation and Registration,

MMBIA, IEEE CVPR, 2001.

A. Yezzi, L. Z llei, et al.: A Variational Framework for Integrating Segmentation and

Registration Through Active Contours, Medical Image Analysis, 7 (2), 2003, 171-185.

L. Z llei, et al.: A Unified Statistical and Information Theoretic Framework for Multimodal

Image Registration, Information Processing in Medical Imaging 2003, LNCS 2732, 366-77.

L. Z llei, et al.: Exploratory Identification of Cardiac Noise in fMRI Images, MICCAI 2003,

Montreal, Canada, LNCS 2878, 475-483.

L. Z llei, et al.: A Unified Statistical and Information Theoretic Framework for Multimodal

Image Registration, #AIM-2004-011.

L. Z llei, et al.: An Introduction to Statistical Methods of Medical Image Registration,

Mathematical Models in Computer Vision: The Handbook, Springer (2005).

L. Z llei et al.: Efficient Population Registration of 3D Data, Computer Vision for Biomedical

Image Applications, ICCV 2005.

L. Z llei: A Unified Information Theoretic Framework for Pair- and Group-wise Registration

of Medical Images, Ph.D. Thesis, CSAIL, MIT, February 2006.

Lilla Z llei (3/5)

L. Z llei et al.: Multi-modal Image Registration Using Dirichlet-encoded Prior Information,

WBIR 2006.

L. Z llei, et al.: A Marginalized MAP Approach and EM Optimization for Pair-wise

Registration, Information Processing in Medical Imaging 2007, LNCS 4584, 662-674.

G. M. Postelnicu, L. Z llei, et al.: Geometry Driven Volumetric Registration, Information

Processing in Medical Imaging 2007, LNCS 4584, 675-686.

A. Mewes, L. Z llei, et al.: Displacement of Brain Regions in Preterm Infants with Non-

Synostotic Dolichocephaly Investigated by MRI, NeuroImage, 36, 2007, 1074-1085.

L. Z llei, et al.: The Impact of Atlas Formation Methods on Atlas-Guided Brain Segmentation,

Statistical Registration: Pair-wise and Group-wise Alignment and Atlas Formation workshop,

MICCAI, Brisbane, Australia, Nov 2007.

M. Maddah, L. Z llei, et al.: A Mathematical Framework for Incorporating Anatomical

Knowledge in DT MRI Analysis, International Symposium on Biomedical Imaging: From

Nano to Macro, May 2008.

M. Maddah, L. Z llei, et al.: Modeling of Anatomical Information in Clustering of White

Matter Fiber Trajectories Using Dirichlet Distribution, Mathematical Methods in Biomedical

Image Analysis, June 2008.

G.M. Postelnicu*, L. Z llei*, et al.: Combined Volumetric and Surface Registration, IEEE

Transactions on Medical Imaging, July 2008 (accepted) (*joint first author)

L. Z llei, et al.: Diffusion Weighted Information Used in a Combined Volumetric and Surface-

based Brain Registration Framework, Human Brain Mapping, June 2009

L. Z llei, W. Wells: On the Optimality of Mutual Information as an Image Registration

Objective Function, International conference of IEEE, ICIP, November 2009

L. Z llei, et al.: Improved Tractography Alignment Using Combined Volumetric and Surface

Registration, NeuroImage 51 (2010), 206-213.

L. Z llei, et al.: Improved Tractography Alignment Using Combined Volumetric and Surface

Registration, Human Brain Mapping, June 2010

L. Z llei, et al.: Non-linear Registration of Intra-subject Ex-vivo and In-vivo Brain

Acquisitions, Human Brain Mapping, June 2010

L. Z llei, et al.: An Efficient Group-wise Spatial Alignment of Medical Image Volumes,

Publications under

submitted to Medical Image Analysis

submission

L. Z llei, et al.: A Unified Statistical and Information Theoretic Framework for Multi-modal

Image Registration, submitted to Transactions on Information Theory

L. Z llei, et al.: A Marginalized MAP Approach to Pair-wise Registration, in preparation

IEEE EMBS International Summer School on Biomedical Imaging, Berder, France, Robust

Invited talks

and Accurate Alignment of Structural MRI Images and Diffusion Tractography (June 18-26,

2010)

Advance Neuroimaging Techniques, Boston, MA, Probabilistic Tractography (October 19-20,

Lilla Z llei (4/5)

2009)

Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Brazil;

Freesurfer Workshop, (March 11-12, 2009)

Section of Biomedical Image Analysis, University of Pennsylvania, Combined Volumetric and

Surface Registration (January 5, 2009)

Max Planck Institute for Human Development, Berlin, Germany; Freesurfer Workshop, (Aug

4-8, 2008)

Sackler Summer Institute, Cornell University, Ithaca, NY; Neuroanatomical Image Analysis,

(June 23, 2008)

Center for Biomedical Imaging, University Hospitals of Geneva, Geneva, Switzerland;

Combined Cortical and Subcortical Spatial Normalization and Tractography Clustering,

(March 7, 2008)

FMRIB, University of Oxford, Oxford, UK; Combined Volumetric and Surface Registration,

(March 4, 2008)

Computer Science and Artificial Intelligence Laboratory, MIT; Combined Volumetric and

Surface Registration; (December 7, 2007)

Department of Electrical and Computer Engineering, University of Iowa; Efficient Group-wise

Registration of Volumetric Data Sets, (January 21, 2007)

EPFL, Lausanne, Switzerland; Efficient Population Registration of 3D Data, (May 1, 2006).

Service Hospitalier Frederic Joliot, Orsay, France; Group-wise Registration of Medical Image

Volumes, (December 19, 2005)

Stochastic Systems Group, CSAIL, MIT; A Unified Information Theoretic Framework for Pair-

and Group-wise Registration of Medical Images, (Nov 16, 2005)

Image Processing and Analysis Group, Yale University; Efficient Population Registration of

3D Data; (June 20, 2005)

Siemens Corporate Research, Princeton, NJ; Efficient Population Registration of 3D Data;

(Aug 2, 2005)

Medical University of Szeged, Oncology Department, Szeged, Hungary; Medical Image

Registration in Practice; (Aug 4, 2004)

Reviewer: IEEE Transactions on Medical Imaging, NeuroImage, IEEE Transactions Service

Scientific Service

on Image Processing, IEEE Transactions on Biomedical Engineering, Pattern Recognition

Letters, Computer Vision and Image Understanding, International Conference on Pattern

Recognition, European Conference on Computer Vision and Computer Vision and Pattern

Recognition.

Co-organizer and host: AI Student Seminar (2001-02), CSAIL Student Seminar (2003-04)

Co-host: Workshop on Statistical Registration: Pair-wise and Group-wise Alignment and Atlas

Formation, MICCAI 2007, Brisbane, Australia ( > 90 participants )

(http://www.nmr.mgh.harvard.edu/martinos/training/nonlocal/miccai07-workshop/)

Co-organizer,lecturer: FreeSurfer Tutorial and Workshop (approx 40 people per event, 4-5

Lilla Z llei (5/5)

events per year), 2006-present, (http://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferWiki)

Chateaubriand Fellow, 2005 (1 year postdoctoral award by the Embassy of France in the USA;

Awards

15 candidates / year)

Best Paper Award: Computer Vision for Biomedical Image Applications, ICCV 2005

Department Head Special Recognition Award, EECS, MIT: June, 2003

Phi Beta Kappa Member, 1999

Outstanding Undergraduate Award: Computing Research Association, Honorable Mention,

1999

Microsoft Women s Technical Scholarship, 1998-99 (full tuition and summer internship offer)

GTE Laboratories Achievement Award, July 1998

C/C++, Matlab, HTML, Java, LISP, Perl

Computer Skills and

Languages

Operating systems: Linux, Unix, Windows, Macintosh

Hungarian (fluent), English (fluent), French (fluent), Spanish (intermediate)

Prof. Bruce Fischl, MGH (******@***.*******.***)

References

Prof. Eric Grimson, MIT (****@*****.***.***)

Prof. Nikos Paragios, ECP (*****.********@***.**)

Prof. William Wells, BWH, HMS (**@***.*******.***)

Prof. Alan Willsky, MIT (*******@***.***)

Contact this candidate