Project Development
Resume:
SHREEKANT DESHPANDE
Email: *********@********.***
Address: *** ********** **
City: HIGHLAND PARK
State: NJ
Zip: 08904
Country: USA
Phone: 732-***-****
Skill Level: Entry
Salary Range: $75,000
Primary Skills/Experience:
Analytical Techniques (HPLC, GC, MS) & Assaying Proteomics & Spectrometry Method Development & Validation Data Modeling & Analysis Project Management & Laboratory Operations
Educational Background:
Doctorate, MEDICINAL AND ANALYTICAL
JAWAHARLAL NEHRU UNIVERSITY, 01/2006 - 11/2010
New Delhi, NEW DELHI, India
Bachelors Degree, PHARMACY
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, 01/1998 - 12/2001
BELGAUM, KARNATKA, India
Job History / Details:
SHREEKANT DESHPANDE
138 Montgomery Street #2N
Highland Park, NJ 08904
Phone: 732-***-****
Email: *********@********.***
ANALYTICAL RESEARCH CHEMIST
Dedicated and motivated professional with a strong background in Medicinal and Analytical Chemistry. Years of successful experience deploying and supporting diverse experimental assay development and drug estimations. Extensive research skills including multistep organic synthesis, characterization, and interpretation of molecules. Able to effectively gather, analyze, author, and evaluate detailed reports while ensuring the accuracy of all documentation. Adept at conducting initial assays, method development and validation, instrument calibration, and routine analysis. Proficient in multitasking and commended for organization, perseverance, efficiency, and project coordination skills. Registered Pharmacist.
AREAS OF EXPERTISE
Analytical Techniques
Data Modeling & Analysis
Method Development
Project Coordination
Research & Analysis
Records & Reporting
Proteomics & Spectrometry
Pharmaceutical Chemistry
Inventory Management
Laboratory Operations
Equipment Calibration
Process Improvement
EDUCATION
JAWAHARLAL NEHRU UNIVERSITY - New Delhi, India
Doctor of Philosophy (Ph.D.) in Medicinal Chemistry 2010
Recipient, Council for Scientific & Industrial Research of India Fellowships
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES - Bangalore, India
Master of Pharmacy in Pharmaceutical Chemistry 2005
Bachelor of Pharmacy 2002
Recipient, University Grant Commission of India Fellowships
RELEVANT EXPERIENCE
EUTECH SCIENTIFIC SERVICES, INC. - Highland Park, NJ 2011-Present
Research Chemist
Perform HPLC and GC method development and validation of active constituents as specified by clients
Conduct routine analysis for various chemical, cosmetic, pharmaceutical, and/or medical devices
Utilize numerous evaluation techniques including ESI/API-MS, ICPMS & Capillary Flow Porometer
Serve in a pivotal role pertaining to lab operations, GLP certification, and critical analytical methods
Manage and maintain chemical inventories, GLP log books, protocols, and equipment calibration
BIOCON INDIA LTD. - Bangalore, India 2004-2005
Research Trainee - Research & Development
Oversaw diverse oriented synthesis of 4-Aryl dihydropyrimidine analogs and their biological activity
Exposed to bioconversion reactions of tachrolimus to pimicrolimus, cGMP, and USFDA documentation
Purified routine samples by HPLC and performed various tasks in support of lab operations
RESEARCH EXPERIENCE
CENTRAL DRUG RESEARCH INSTITUTE - Lucknow, India 2006-2011
Senior Research Fellow
Utilized peptide chemistry to develop anti-parasitic lead compounds by multistep organic synthesis
Characterized and purified synthesized organic compounds using different instrumental techniques
Established bio-physical studies and assays using UV spectroscopy and Isothermal Titration Calorimetry
Conducted in-depth studies on quantitative structure activity relationships with statistical software
Part of a specialized team focusing on synthetic drug design to treat breast cancer, HIV, and diabetes
INDIA INSTITUTE OF SCIENCES - Bangalore, India 2005-2006
Research Fellow
Analyzed and identified proteins by Mass spectroscopy including MALDI-TOF and proteomics
Performed chemical-assisted fragmentation of peptides, 2D gel electrophoresis, and protein purification
Helped to recognize and categorize cell proteins and their peptides using ExPASy, Mascot search
ADDITIONAL EXPERIENCE
SAROJ INSTITUTE OF TECHNOLOGY - Lucknow, India 2011
Adjunct Faculty (Pharmacy Department)
CENTRAL DRUG RESEARCH INSTITUTE - Lucknow, India 2008-2010
Trainer, Graduate Students
TECHNICAL SUMMARY
ANALYTICAL CHEMISTRY:
HPLC, GC and CE * MALDI-TOF and ESIMS * UV, FTIR and Florescent Spectroscopies * CD and ORD * Functional and structural interpretation * Critical analytical procedures * Knowledge of approved SOPs, compendia, and other regulatory procedures
MEDICINAL CHEMISTRY:
Wet Chemistry * Lead identification and optimization * Quantitative Structure Activity Relationship (QSAR) * Data Analysis * Anti-parasitic and anti-breast cancer activity * Ligand-Based as well as Target-Based Drug Designing * Elementary Pharmacology and animal handling
COMPUTER SKILLS:
Microsoft Word, Excel, PowerPoint * Chemstation * Systat, GraphPad PRISM * Mascot, ExPASy * MOE, Pymol, AutoDock, and Unix-based operating systems (Sybyl)
PUBLICATIONS
1. Kr Maurya, S., Rai, A., Rai, N., Deshpande, S., Jain, R., Reddy, M.K., Prabhakar, Y.S., Bandyopadhay, S. 2012 Cypermethrin Induces Astrocyte Apoptosis by the Disruption of the Autocrine/Paracrine Mode of Epidermal Growth Factor Receptor Signaling. Toxicol Sci. 125: 473-487.
2. Deshpande S., Jaiswal S., Katti S.B., Prabhakar Y.S. 2011 CoMFA Analysis of Tetrahydroquinolines as Antimalarial Agents: Inhibitors of Plasmodium falciparum Protein Farnesyltransferase. SAR QSAR and Environ. 12: 473-488.
3. Deshpande S., Singh R., Goodarzi M., Katti S.B., Prabhakar Y.S. 2011 Consensus Features of CP-MLR and GA in Modeling HIV-1 RT Inhibitory Activity of 4- Benzyl/benzoyl pyridin-2-one Analogues. J. Enzym. Inhbn. Med. Chem. 26: 696-705.
4. Chakravarti, B., Dwivedi, S.K.D., Deshpande, S., Samanta, K., Siddiqui, J.A. Kumar, A. Panda, P. Prabhakar, Y.S., Sanyal, S., Bid, H.K., Konwar, R., Chattopdhyay, N. 2011 A benzoxazepin derivative inhibits cell survival and induces aopotosis of MCF-7 by blocking insulin-like growth factor I receptor signaling, and inhibits xenograft tumor growth in mice. Mol. Cell. Endocrinol. Elsevier, 338: 68.
5. Deshpande S., Gupta M.K., Prabhakar Y.S. 2010 Multi-Model Environment as a Rational Approach for Drug Design: An Experience with CP-MLR. The IUP Journal of Chemistry, Vol III(1),
6. Deshpande S., Solomon V.R., Katti S.B., Prabhakar Y.S. 2009 Topological descriptors in modelling antimalarial activity: N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine as prototype. J. Enzym. Inhbn. Med. Chem, 24(1): 94.
7. Goodarzi M., Deshpande S., Murugesan V., Katti S.B., Prabhakar Y.S. 2009 Is Feature Selection Essential for ANN Modeling
QSAR Comb Sci. 28, 1487.
8. Ravi Shankar, Chakravarti B., Singh U.S., Ansari M.I., Deshpande S., Dwivedi S.K.D., Bid H.K., Konwar R., Kharkwal G., Chandra V., Dwivedi A., Hajela K. 2009 Synthesis and Biological Evaluation of 3, 4, 6-Triaryl -2-Pyranones as a Potential New Class of Anti-breast Cancer Agents. Bioorg. Med. Chem 17(11): 3847.
9. Kumar S., Deshpande S., Chandra V., Kitchlu S., Dwivedi A., Nayak V.L., Konwar R., Prabhakar Y.S., Sahu D. P. 2009 Synthesis and biological evaluation of 2,3,4-triarylbenzopyran derivatives as SERM and therapeutic agent for breast cancer. Bioorg. Med. Chem. 17: 6832.
REFERENCES
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