High School Electrical

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*****.****@*****.***

Brian A. Wilt, Ph.D.

Redwood City, CA 94062

610-***-****

Education

Stanford University Palo Alto, CA 2007 2012

Ph.D in Applied Physics in Mark Schnitzer Lab. M.S. conferred 2009.

Employed signal detection theory and estimation theory to establish the fundamental limits of optical tech-

nologies for monitoring cellular activity in the brain.

Assembled a statistical framework for quantifying the performance of the lab s uorescence microscopes.

Explored new candidates for neural activity readout, including voltage sensors and optoacoustic approaches.

Implemented optimal ltering strategies for neuronal spike detection in bulk cellular optical recordings.

Awarded Bio-X Graduate Student Fellowship.

Coursework: Computational Neural Networks, Large-Scale Neural Modeling, Modern Applied Statistics: Learn-

ing, Engineering Optics, Advanced Imaging Lab in Biophysics.

Massachusetts Institute of Technology Cambridge, MA 2003 2007

B.S. in Physics. Minor in Mathematics. Minor in Management from the Sloan School. GPA: 4.7/5.

Coursework: Numerical Analysis, Linear Partial Di erential Equations, Applied Statistics, Optimization.

Activities: Sigma Chi Fraternity (President), MIT Tour Guide, certi ed high school educator.

Organized Sigma Chis 125th Anniversary Reunion; 25% of alumni attended (350 guests).

Experience

Decisive Analytics Corporation Arlington, VA 2007

Intern. Implemented novel solution to multiple-target tracking problem using metropolis sampling and Kalman

ltering in Java with Swing visualization and multi-threading.

Presented algorithm and results in hour long colloquium to division, including a live demo of the software.

European Organization for Nuclear Research (CERN) Geneva, Switzerland 2005 2007

Paul E. Gray Research Fellow.

Performed feasibility study for a method of measuring the charged multiplicity of p+p events in CMS.

Designed and administered hardware testing application for CMS Data Acquisition group; paced hundreds of

electrical components through multi-stage tests, reported weekly progress to group.

Trifecta Technologies, Incorporated Allentown, PA 2000 2004

Intern. Mastered many developing web technologies to help customers implement IT solutions.

Spearheaded database development for a redesign of major RNC campaign donation website.

Assembled crucial Oracle database reporting elements for a major US pharmaceutical company to improve

their drug distribution reporting system.

Technical Skills

Specialties. Matlab, statistics, SQL, scripting languages (Perl, Python), web technologies (PHP, HTML, CSS),

Java, Adobe CS5, L TEX.

A

Exposure. Linux, Database Administration (Oracle, MySql), C++, Mathematica, image processing (OpenCV),

machine learning techniques.

Activities / Honors

Bio-X Fellowship (2008 2011), Eton College Annenberg Fellowship Finalist (2007), Paul E. Gray Fellowship (2006).

Publications

Brian A. Wilt, James E. Fitzgerald, and Mark J. Schnitzer. Photon shot noise limits on optical detection of

neuronal spikes and estimation of spike timing. Submitted to Biophys. J. (2011).

Brian A. Wilt and Mark J. Schnitzer. Limits of neuronal spike detection in optical imaging due to photon

shot noise. Poster presented at Fluorescent Proteins and Biological Sensors II (2009). Howard Hughes Medical

Institute Janelia Farm.

Brian A. Wilt, Laurie D. Burns, Eric T.W. Ho, Kunal K. Ghosh, Eran A. Mukamel, and Mark J. Schnitzer.

Advances in light microscopy for neuroscience. Ann. Rev. Neurosci. (2009). 32:435 506. (32 citations)

Personal

Coaches volleyball with his wife (5th ranked 12U team in USA in 2011), guitar and piano, Dvorak keyboard enthusiast.

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