Assistant Research
Resume:
Name: Leo
Pezzementi
Position: Professor of Biology
Address: Division of Science and Mathematics, Birmingham-Southern
College,
*** *********** ****, **********, ***bama 35254
Phone: 205-***-****/4870
Fax: 205-***-****
E-mail: ********@***.***
EDUCATION
State University of New York at Stony Brook,
and Pharmacological Sciences Program. Dept. of Biochemistry. Ph.D. awarded
August 1982.
La Salle College, Philadelphia, PA. Biology major. B.A. awarded May
1975.
PROFESSIONAL EXPERIENCE
University of California
at San Diego School of Medicine,
La Jolla, California. Visiting Scholar (January 2003-July
2003). Laboratory of Dr. Palmer Taylor, Department of Pharmacology.
Ecole
Normale Sup rieure,, Paris, France. Invited
Professor (June
1992-August 1992). NSF-CNRS Fellow (July 1990-July 1991).
Laboratory of Dr. Jean Massouli .
Case-Western
Reserve University School
of Medicine, Cleveland, OH. Visiting Scientist (June 1988-August
1988). Laboratory of Dr. Terrone Rosenberry, Department of
Pharmacology.
University
of Alabama at Birmingham,
University of Alabama School of Medicine, Birmingham, AL. Adjunct
Assistant Professor of Psychiatry (1988-1992).
Birmingham-Southern
College, Birmingham, AL.
Chair, Division of Science and Mathematics (1997-2001). Professor
of Biology (1996) Associate Professor of Biology (1988-1996).
Assistant Professor of Biology (1985-1988).
Oberlin College, Oberlin, OH. Visiting Assistant Professor of
Biology (1983, 1984-1985) and Chemistry (1984).
Franklin and Marshall College, Lancaster, PA. Visiting Assistant
Professor of Biology (1982-1983).
RESEARCH INTERESTS
Acetylcholinesterase
(AChE) is a serine hydrolase whose primary function is the hydrolysis of
acetylcholine at cholinergic synapses of animals. Humans and other vertebrates
have another evolutionarily related cholinesterase, butyrylcholinesterase
(BChE), which appears to act as a scavenger of a variety of toxins in the body.
Cholinesterases (ChEs) are of considerable physiological, pharmacological,
toxicological, and insecticidal interest. The known structures of vertebrate AChE and
BChE, molecular modeling, site-directed mutagenesis, and in vitro
expression of AChE and BChE from various species have allowed a comparative
biochemical approach that has identified residues comprising important catalytic
subsites in the enzymes.
We
have extended this comparative approach to include ChE1 and ChE2 from the
invertebrate chordate amphioxus and AChE from the sea squirt, organisms that
occupy key positions in
evolution; and to the intermediate ChE of a bony fish, the medaka - all ChEs with unique properties. This approach has
been profitable and has provided additional insights into
the structure, function, and evolution of ChEs, revealing fundamental catalytic
and structural requirements, and
suggesting the design of more specific, effective, and safer
pesticides.
GRANTS
($559,029 for BSC; $1,059,029
total)
National Institutes of
Health Academic Research Enhancement Award. “Acetylcholinesterase: A Comparative
Biochemical Approach.” $201,000.
Award No. 1 R15
GM072510-01.(April
2005-March 2009).
W. M. Keck Foundation Grant. "Focusing on the Reform of
Science Education for Non-Science Majors." $500,000 to Trinity University on
behalf of the Associated Colleges of the South, with Ed Roy, Wayne Anderson,
Preston Miles, John Snyder, Tim Ward, Andy Newcomb, and Beth Bowser. (August
2003-August 2006).
National Science Foundation Course, Curriculum, and Laboratory
Improvement Grant. "A Collaborative Recombinant DNA Technology
Course with Laboratory."
$20,383. Grant No. DUE-9950225. (August 1999-July 2001).
National Science Foundation Research at Undergraduate
Institutions Grant. "Evolution of Cholinesterase In Vivo and In
Vitro. $111,684. Grant No.
IBN-9319354. (May 1994-April 1998).
National Science Foundation Research at Undergraduate
Institutions Grant. "Evolution of Acetylcholinesterase." $124,357. Grant No. BNS-9010710.
(Sept. 1990-February 1994).
National Institutes of Health -- Centre National de la Recherche
Scientifique Fellowship. Laboratory of Dr. Jean Massouli,
Laboratoire de Neurobiologie, Ecole Normale Sup rieure.
120,000FF. (July 1990-June 1991).
National Institutes of Health Academic Research Enhancement
Award. "Characterization of Lamprey
Acetylcholinesterase." $47,559. Award No. 1 R15 NS24943-01
(August 1987-August 1990).
National Science Foundation College Science Instrumentation
Program. "Equipment for a Modern Undergraduate Cell Biology
Laboratory." $22,046. Award No. CSI-8750089. (July
1987-December 1989).
Research Corporation Cottrell College Science Grant.
"Characterization of Molecular Forms of Acetylcholinesterase
from Skeletal Muscle of Lamprey." $8,000. (December
1984-October 1988).
SELECTED PROFESSIONAL RESPONSIBILITIES, HONORS, ORGANIZATIONS
Phi Beta Kappa, October 2006.
Biology Councilor, Council on Undergraduate Research (1989-1992), member (1988-present), editor
of Research in Biology at Primarily Undergraduate Institutions,
3rd edition (1993-1995), institutional liaison (1994-1998;
2001-2005).
Society
for Neuroscience (1982-1989,
1992-2001).
American Society for Biochemistry and Molecular
Biology (2000-present).
Reviewer, National Science Foundation, Instrumentation and
Laboratory Improvement, Research at Undergraduate Institutions,
Beginning Investigator, and Pre-doctoral Fellowship Programs; National Institutes of
Health, Academic Research Enhancement Award Program.
NIH Predoctoral Traineeship in Pharmacology (1977-1980).
SELECTED CAMPUS RESPONSIBILITIES
Co-Chair, Science Building Planning Committee (1998-2002).
Construction of the $24 million Elton
B. Stephens Science Center
was completed in May 2002.
Chair, General Education Committee
(1997-1998), led the development of "Expanding the Paradigm of General Education."
Faculty Advisory Committee (1992-1996,
2003-2006); Chair (1993-1994), led development of “Recommendations to Improve
Faculty Morale”; Chair (2003-2004), represented faculty views in the
presidential search process; Co-chair (2004-2005), led revision of the charge of
the committee as defined in the Faculty Handbook and Bylaws; Co-chair
(2005-2006), led development of Faculty Ecumenical Statement, and discussions on
the future of the College, including transition from NCAA Division I to Division
III; elected member (1992-1994, 1995-1996, 2003-2006).
Quality Enhancement Program, Topic Selection Committee
(2011-2012), member; Development Committee (2012-2013), Chair, Undergraduate
Research Sub-committee.
Faculty Development Committee, elected member (1989-1990).
Promotion and Tenure Committee, elected member (2001-2002).
Faculty Advisor, Tri-Beta Biological Honor Society (1987-1990;
1991-1994), initiated campus-wide aluminum recycling program.
Radiation Safety Officer (1987-present), obtained radioisotope
license for Biology Department.
Research
Integrity Officer (1995-present),
helped establish guidelines for investigation of scientific
fraud.
21st Century Coordinating Committee, member (1995-2000).
PUBLICATIONS (undergraduate students are underlined)
Leo Pezzementi, Eric Krejci, Arnaud Chatonnet, Murray
Selkirk, and Jacqui Matthews. 2012.
A tetrameric acetylcholinesterase from the parasitic nematode Dictyocaulus
viviparus associates with the vertebrate tail proteins PRiMA and ColQ.
Mol. Biochem. Parasitol. 181, 40-48.
Leo Pezzementi, Florian Nachon, and Arnaud Chatonnet.
2011.
Evolution of acetylcholinesterase and butyrylcholinesterase in the vertebrates:
an atypical butyrylcholinesterase from the medaka Oryzias latipes.
PLoS One, 6, e17396
Leo Pezzementi and Arnaud Chatonnet. 2010.
. Chem. Biol. Interact.,
187, 27-33.
Brian Perrin,
Melissa Rowland, Matthew Wolfe, Igor Tsigelny, and Leo Pezzementi. 2008.
Thermal denaturation of wild type and
mutant recombinant acetylcholinesterase
from amphioxus: effects of the temperature of in vitro expression and of
reversible inhibitors. Invert. Neurosci., 8, 147-155.
Melissa
Rowland,
Igor Tsigelny, Matthew Wolfe, and Leo Pezzementi. 2008. Inactivation of
an invertebrate acetylcholinesterase by sulfhydryl reagents: A reconsideration
of the implications for insecticide design.
Chem. Biol. Interact.,
175, 73-75.
Adam Frederick,
Igor Tsigelny, FrancisCohenour, Christopher Spiker, Eric Krejci,
Arnaud Chatonnet, Stefan Bourgoin, Greg Richards, Tessa Allen,
Mary Hollace Whitlock, and Leo Pezzementi. 2008.
Acetylcholinesterase from the invertebrate Ciona intestinalis is capable
of assembling into asymmetric forms when co-expressed with vertebrate collagenic
tail peptide. FEBS J., 275, 1309-1322.
Natalie Jennings, Leo
Pezzementi, A. L. Lawrence, and Stephen A. Watts. 2008.
Acetylcholinesterase in the sea urchin Lytechinus variegatus:
Characterization and developmental expression in larvae. Comp Biochem
Physiol B Biochem Mol Biol.
Leo
Pezzementi. 2008. Science for All: The Associated Colleges of the South Story.
Project Kaleidoscope.
http://www.pkal.org/documents/ScienceForAllACS.cfm, pp. 1-5.
Raj Patel, Rachael Sanders,
Lance Brown, Stephanie Baker, Igor Tsigelny, and Leo Pezzementi.
2006.
A tryptophan in the bottleneck of the catalytic gorge of an invertebrate
acetylcholinesterase confers relative resistance to carbamate and
organophosphate inhibitors. Cell Bioch. Biophys., 46, 253-264.
Leo Pezzementi, Melissa Rowland,
Matthew Wolfe, and Igor Tsigelny. 2006.
Inactivation of an invertebrate acetylcholinesterase by sulfhydryl reagents: the roles of two cysteines in the
catalytic gorge. Invert. Neurosci., 6, 47-55.
Leo Pezzementi, Jianxin Shi, David A. Johnson,
Zoran Radic, Aileen Boyd, and Palmer Taylor. 2005.
Ligand-induced
conformational changes in
residues flanking the active site gorge of acetylcholinesterase. Chem. Biol.
Interact., 157-158, 413-414.
Leo Pezzementi, Kim Johnson, Justin Cotney, Andrew
Barker, and Elizabeth Manning. 2004. Amino acids involved in
substrate and inhibitor specificity in cholinesterase 2 from amphioxus. In
Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects,
(N.C. Inestrosa and E.O. Campos, eds.), MIFAB: Santiago, Chile, pp. 223-224.
Leo Pezzementi, Kim Johnson, Igor Tsigelny, Justin
Cotney, Andrew Barker, Elizabeth Manning, and Sarah
Merritt. 2003.
Amino acids defining the acyl pocket of an invertebrate cholinesterase,
Comp. Biochem Physiol. B. Mol. Biol. Biochem. 136, 813-832.
Leo Pezzementi and Joy F. Johnson. 2002.
A
collaborative, investigative recombinant DNA technology course
with laboratory. Biochemistry and Molecular Biology
Education, 30, 376-379.
James Scott McClellan, William Blake Coblentz, Mathew Sapp,
Gabriel Rulewicz, David Isaac Gaines, Ashley Hawkins, Caroline
Ozment, Amy Bearden, Sarah Merritt, John Cunningham, Elizabeth
Palmer, Amir Contractor, and Leo Pezzementi. 1998. cDNA cloning, in vitro expression, and
biochemical characterization of cholinesterase 1 and
cholinesterase 2 from amphioxus: comparison with cholinesterase 1
and cholinesterase 2 produced in vivo. Eur. J. Biochem., 258, 419-429.
Leo Pezzementi, David
Sutherland, Michael Sanders, Weily Soong, Daniel Milner, James
Scott McClellan, Mathew Sapp, William Blake Coblentz, Gabriel
Rulewicz, and Sarah Merritt. 1998. Structure and function of
cholinesterases from agnathans and cephalochordates: implications
for the evolution of the cholinesterases. In Structure and
Function of Cholinesterases and Related Proteins, (B.P. Doctor,
P. Taylor, D.M. Quinn, R.L. Rotundo, and M.K. Gentry, eds.),
Plenum Press: New York, pp. 105-110.
David Sutherland, Scott
McClellan, Danny Milner, Weily Soong, Neal Axon, Michael Sanders,
Alison Hester, Yu-Hsing Kao, Ted Poczatek, Sheri Routt, Amir
Contractor and Leo Pezzementi. 1997.
Two cholinesterase
activities and genes are present in amphioxus. Journal of Experimental Zoology, 277, 213-229.
Michael Sanders, Bonnie Mathews, David Sutherland, Weily
Soong, Harry Giles, and Leo Pezzementi. 1996. Biochemical and molecular characterization
of acetylcholinesterase from the hagfish Myxine glutinosa.
Comp. Biochem. Physiol. 115B, 97-109.
Leo Pezzementi. 1994. Research in Biology at Primarily
Undergraduate Institutions. Council on Undergraduate Research,
Collegiate Research Association of Biologists: Asheville, NC, 344
pp.
Jean Massouli, Leo Pezzementi, Suzanne Bon, Eric Krejci, and
Fran ois-Marie Vallette. 1993. Molecular and cellular biology of
cholinesterases. Progress
in Neurobiology 41, 31-91.
Christopher Atkins and Leo Pezzementi. 1993. Developmental changes in the molecular
forms of acetylcholinesterase during the life cycle of the
lamprey. Comparative
Biochem. Physiol. 106B, 369-372.
Leo Pezzementi, Michael Sanders, Todd Jenkins, Dan Holliman,
Jean-Pierre Toutant, and Ronald J. Bradley. 1991. Structure
and function of cholinesterase from amphioxus. In,
Cholinesterases: structure, function, mechanism, genetics and
cell biology (J. Massouli, F. Bacou, E. A. Barnard, A.
Chatonnet, B.P. Doctor, and D.M. Quinn, eds.). American Chemical
Society: Wash., D.C., pp 24-31.
Howell Heflin/Leo Pezzementi. 1990. Remarks of Dr. Leo Pezzementi,
Birmingham-Southern College.
Congressional Record-Senate S10899.
Leo Pezzementi. 1990. NIH AREA Program from the perspective of
undergraduate research. Council on Undergraduate Research
Newsletter 11, 57-60.
Leo Pezzementi, Hugh C. Nickson, Robert Dunn, and Ronald J.
Bradley. 1989. Molecular forms of acetylcholinesterase
from the skeletal muscle of the ammocoete of the lamprey
Petromyzon marinus. Comp. Biochem. Physiol. 92B, 385-387.
Leo Pezzementi, Hugh C. Nickson, and Ronald J. Bradley.
1988. Lamprey brain contains globular and asymmetric forms of
acetylcholinesterase. Neurochem. Int. 12, 131-135.
Leo Pezzementi, Ellen J. Reinheimer, and Maureen
Pezzementi. 1987. Acetylcholinesterase from the skeletal
muscle of the lamprey Petromyzon marinus exists in globular and
asymmetric forms. J. Neurochem. 48, 1753-1760.
Scott W. Melanson, Chang-Hyon Yun, Maureen Pezzementi, and
Leo Pezzementi. 1985. Characterization of acetylcholinesterase
activity from Drosophila melanogaster. Comp. Biochem. Physiol. 81C, 87-96.
Mark Schneider, Bih-Hwa Shieh, Leo Pezzementi and Jakob Schmidt.
1984. Trifluoperazine stimulates acetylcholine
receptor synthesis in chick skeletal muscle cell cultures.
J. Neurochem. 42, 1395-1401.
Bih-Hwa Shieh, Leo Pezzementi and Jakob Schmidt. 1983. Extracellular potassium and the regulation
of acetylcholine receptor synthesis in chick skeletal muscle cell
cultures. Brain Research,
259-265.
Leo Pezzementi and Jakob Schmidt. 1981. Ryanodine alters acetylcholine receptor
synthesis in chick skeletal muscle cell cultures.
J. Biol. Chem. 256, 125**-*****.
Leo Pezzementi and Jakob Schmidt. 1981. Rapid modulation of acetylcholine receptor
synthesis. FEBS Letters
135, 103-106.
Nisson Schechter, Indhira C. Handy, Leo Pezzementi, and Jakob
Schmidt. 1978. Distribution of a-bungarotoxin binding
sites in the central nervous system and the peripheral organs of
the rat. Toxicon 16,
245-251.
ABSTRACTS
Leo Pezzementi, Abigail E. Dy,
Lauren Nicholas S. Herrera, Avirath N. Purohit, Megan M. Sandlin, Janelle T.
West. 2012. Do the MRL proteins – MIG-10, RIAM, and Lamellipodin – interact
with acetylcholinesterase and butrylcholinesterase? Eleventh International
Meeting on Cholinesterases (Kazan, Russia): Program and Abstracts, 103.
Leo
Pezzementi, Nicolas Lenfant, and Arnaud Chatonnet. 2012. Cholinesterases in
Saccoglossus kowalevskii (hemicordata): cloning, in vitro expression,
and molecular characterisation. Eleventh
International Meeting on cholinesterases (Kazan, Russia): Program and Abstracts,
217.
Leo Pezzementi and
Arnaud Chatonnet. 2009. Evolution of vertebrate cholinesterases: an intermediate
cholinesterase from the teleost fish, the medaka (Oryzias latipes).
Tenth International Meeting on cholinesterases (Sibenik, Croatia): Program and Abstracts, 34.
Leo Pezzementi and
Arnaud Chatonnet. 2009. Evolution of cholinesterases in the animal kingdom.
Tenth International Meeting on cholinesterases (Sibenik, Croatia): Program and Abstracts, 34.
Leo Pezzementi, Brian Davis, Robert Kress, Brendan Burn,
Ashley Russell, Elizabeth Molony, Tia Barclay, Jeffrey Lucas, Julie Johnson,
Brian Perrin, Claire Anderson, Igor Tsigelny, Eric Krejci. 2009. The effect of
Ser20 T-peptide mutations on the tetramerization of Ciona intestinalis
AChE and its association with the proline-rich membrane anchor, PRiMA.
Tenth International Meeting on cholinesterases (Sibenik): Program and Abstracts,
84-85.
Adam Frederick,
Igor Tsigelny, Frances Cohenour, Christopher Spiker, Eric Krejci,
Arnaud Chatonnet, Stefan Bourgoin, Greg Richards, Tessa Allen,
Mary Hollace Whitlock, and Leo Pezzementi. 2007. In vitro
expression, kinetic, pharmacologic, molecular, and evolutionary anayses, and
molecular modeling of a recombinant acetylcholinesterase from the invertebrate
urochordate Ciona intestinalis: assembly of asymmetric forms with ColQ.
Ninth International Meeting on Cholinesterases (Suzhou, China): Program Book, 24.
Melissa Rowland,
Igor Tsigelny, Matthew Wolfe, and Leo Pezzementi. 2007. Inactivation of
an invertebrate acetylcholinesterase by sulfhydryl reagents and elevated
temperature. Ninth International Meeting on Cholinesterases (Suzhou, China): Program Book,
87.
Natalie A. Jennings, Leo Pezzementi, Micki L.
Powell, A.L. Lawrence, and Stephen A. Watts. 2007. Characterization of
acetylcholinesterase in the sea urchin Lytechinus variegates. Ninth
International Meeting on Cholinesterases (Suzhou, China): Program Book, 94.
Raj Patel,
Rachel Sander, Lance Brown, Stephanie Baker, Igor Tsigelny,
and Leo Pezzementi. 2007. A tryptophan in the bottleneck of the catalytic gorge
of an invertebrate acetylcholinesterase confers resistance to carbamates and
organophosphate inhibitors. Ninth International Meeting on Cholinesterases (Suzhou,
China):
Program Book, 114.
Leo Pezzementi, Kim Johnson, Justin Cotney, Andrew
Barker, and Elizabeth Manning. 2004. Amino acids
involved in substrate and inhibitor specificity in cholinesterase
2 from amphioxus. In Cholinesterases in the Second Millennium: Biomolecular and
Pathological Aspects, (N.C. Inestrosa and E.O. Campos, eds.), MIFAB: Santiago,
Chile, p.370.
Leo Pezzementi, Justin Cotney, and Brett Earley.
2002. Probing the molcular basis of the substrate and inhibitor
specificities of cholinesterase 1 and cholinesterase 2 from
amphioxus. Experimental Biology, ASBMB, 2002, 426.1.
Leo Pezzementi and Joy F. Johnson. 2002. A collaborative
recombinant DNA course with laboratory. Experimental Biology, ASBMB, 2002, 684.8.
Leo Pezzementi and Larry Fish.
2001. A collaborative recombinant DNA course with laboratory. The
Journal of the Alabama Academy of Science, 72, 125.
Leo Pezzementi, David
Sutherland, Michael Sanders, Weily Soong, Daniel Milner, James
Scott McClellan, Mathew Sapp, William Blake Coblentz, Gabriel
Rulewicz, and Sarah Merritt. 1998. Structure and function of
cholinesterases from agnathans and cephalochordates: implications
for the evolution of the cholinesterases. The Sixth International
Meeting on Cholinesterases (La Jolla, CA): Program and Abstracts, 5.
Leo Pezzementi, David
Sutherland, Michael Sanders, Weily Soong, Daniel Milner, James
Scott McClellan, Mathew Sapp, William Blake Coblentz, Gabriel
Rulewicz, and Sarah Merritt. 1998. Pharmacological and
molecular analysis of cholinesterases from agnathans and
cephalochordates: implications for the evolution of resistance to
cholinesterase inhibitors. Sixth International Meeting on Cholinesterases (La
Jolla, CA): Program and Abstracts, 17.
James Scott McClellan, William
Blake Coblentz, Mathew Sapp, Gabriel Rulewicz, David Isaac
Gaines, Ashley Hawkins, Caroline Ozment, Amy Bearden, Sarah
Merritt, John Cunningham, Elizabeth Palmer, Amir Contractor, and
Leo Pezzementi. 1998. cDNA cloning, in vitro expression, and
biochemical characterization of cholinesterase 1 and
cholinesterase 2 from amphioxus: comparison with cholinesterase 1
and cholinesterase 2 produced in vivo. Sixth International
Meeting on Cholinesterases (La Jolla, CA): Program and Abstracts, A5.
Leo Pezzementi, Rick Jotani,
Bonnie Mathews, Danny Milner, and Weily Soong. 1995 Is
butyrylcholinesterase present in primitive chordates? Soc. Neurosci. Abstr. 20, 839.4.
Leo Pezzementi, Michael
Sanders, Michael Miller, Kristin Glaese, and Lee Ann Shannon.
1994. Identification of globular and asymmetric forms of an
intermediate cholinesterase in amphioxus: implications for the
evolution of the cholinesterases in the vertebrates. Soc. Neurosci. Abstr. 20, 409.10.
Leo Pezzementi, Weily Soong,
David Sutherland, Michael Sanders and Harry Giles. 1993.
Evolutionary origins of cholinesterase duality in the
vertebrates. Soc. Neurosci. Abstr. 19, 378.12.
Leo Pezzementi, Weily Soong,
David Sutherland, Michael Sanders and Harry Giles. 1993.
Molecular probing of the evolutionary origins of cholinesterase
duality (Abstr.). J. Neurochem. 61 (Suppl.), S146D.
Leo Pezzementi, Michael
Sanders, Todd Jenkins, Jean-Pierre Toutant and Ronald J.
Bradley. 1990. Structure and Function of cholinesterase from
amphioxus. Third International Meeting on Cholinesterases (La Grande Motte,
France), p.5.
Leo Pezzementi. 1989. Evolutionary
and developmental implications of the structure of
acetylcholinesterase from the lamprey Petromyzon marinus. J.
Alabama Acad. Sci. 60, 125.
Leo Pezzementi, Hugh Nickson,
Robert Dunn and Ronald J. Bradley. 1987. Molecular forms of
acetylcholinesterase from adult lamprey brain and ammocoete
skeletal muscle. Soc. Neurosci. Abstr. 13, 286.10.
Leo Pezzementi, Ellen
Reinheimer and Maureen Pezzementi. 1985. Acetylcholinesterase
from lamprey skeletal muscle is found in globular and asymmetric
forms. Soc. Neurosci. Abstr. 11, 12.17.
Leo Pezzementi. 1984.
Acetylcholinesterase from the skeletal muscle of the lamprey.
1984. Soc. Neurosci. Abstr. 10, 140.7.
Mark Schneider, Bih-Hwa Shieh, Leo
Pezzementi and Jakob Schmidt. 1983. The effect of trifluoperazine
on AChR synthesis in cultured chick myotubes. Soc. Neurosci.
Abstr. 9, 18.1.
Bih-Hwa Shieh, Leo Pezzementi and
Jakob Schmidt. 1982. Membrane potential and the regulation of
AChR synthesis in embryonic chick skeletal muscle cells. Soc. Neurosci. Abstr. 8, 205.9
Leo Pezzementi and Jakob Schmidt.
1981. Acetylcholine receptor synthesis of chick skeletal muscle
cell cultures is altered by ryanodine. Soc. Neurosci. Abstr. 7,
259.4.
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