Medical University

Location:

Springfield, IL

Posted:

October 03, 2012

Contact this candidate

Resume:

Martin D. Burke

Curriculum Vitae

Early Career Scientist phone: 217-***-****

Howard Hughes Medical Institute fax: 217-***-****

Assistant Professor of Chemistry email: *****@***.****.***

University of Illinois at Urbana-Champaign web site: http://www.scs.uiuc.edu/burke/

454 Roger Adams Laboratory

600 South Mathews Ave.

Urbana, IL 61801 Born: Feb. 5, 1976, Westminster, MD

Education

1998-2005 National Institutes of Health Fellow in the Medical Scientist Training Program

Harvard Medical School/Massachusetts Institute of Technology

Division of Health Sciences and Technology: Boston, Massachusetts

Degree awarded: M.D.

1999-2003 Howard Hughes Medical Institutes Predoctoral Fellow

Harvard University, Department of Chemistry and Chemical Biology

Cambridge, Massachusetts, Degree Awarded: Ph.D.

Thesis advisor: Professor Stuart L. Schreiber

1994-1998 Johns Hopkins University, Baltimore, Maryland

Degree Awarded: B.A. Chemistry

Research advisors: Professors Henry Brem and Gary H. Posner

Appointments

August 2005 Assistant Professor, Department of Chemistry

University of Illinois at Urbana-Champaign, Urbana, Illinois

Sept. 2009 Affiliate Faculty, Department of Biochemistry, UIUC

October 2009 Early Career Scientist, Howard Hughes Medical Institute

Awards and honors

2010 Bristol-Myers Squibb Lectureship at Harvard University

2010 Frontiers in Chemistry Lectureship at The Scripps Research Institute

2010 Novartis Lectureship at The University of California Berkeley

2009 Howard Hughes Medical Institute Early Career Scientist

2009 Alfred P. Sloan Foundation Research Fellowship

2009 Bristol-Myers Squibb Unrestricted Grant in Synthetic Organic Chemistry Award

2009 Eli Lilly Grantee Award

2009 AstraZeneca Excellence in Chemistry Award

2009 Amgen Young Investigator Award

2009 Bristol-Myers Squibb Lectureship at Princeton University

2009 Thieme Chemistry Journals Award

2008 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence

2008 Arnold and Mabel Beckman Foundation Young Investigator Award

2008 World s 35 Top Innovators Under 35 Technology Review Magazine

2008 National Science Foundation CAREER Award

2008 Scientist to Watch The Scientist Magazine2007 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence

2006 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence

Martin D. Burke, PhD, MD

2005 ACS Petroleum Research Foundation Type G Award

2005 Camille and Henry Dreyfus New Faculty Award

2005 Henry Asbury Christian Award, Harvard Medical School

2003 National Institutes of Health Medical Scientist Training Program Fellowship

2000 Howard Hughes Medical Institute Predoctoral Fellowship

1998 Hunterian Research Award - Johns Hopkins Department of Neurosurgery

1997 Phi Beta Kappa - Junior Year, Johns Hopkins University

1997 Howard Hughes Undergraduate Research Fellowship - Johns Hopkins University

1997 Provost s Undergraduate Research Award - Johns Hopkins University

1994-1998 Dean s List - Johns Hopkins University

1994-1998 Beneficial Hodson Scholar - Johns Hopkins University

1994-1998 Maryland Distinguished Scholar

Publications http:

Synthesis:

Iterative Suzuki-Miyaura Coupling of B-Protected Haloboronic Acid Building Blocks. J.

Am.

Chem. Soc. 2007, 129, 6716-6717.

Highlighted in Chemical and Engineering News: Masks unveil new synthetic routes

2007, 85, 63-64.

Highlighted in SynFacts 2007, 10, 1007

Highlighted in Synform 2008, 5, 58-59.

Highlighted in Chemistry World February 2008, p. 27.

Reviewed in Accounts of Chemical Research 2008, 41, 1461-1473.

Martin D. Burke, PhD, MD

Highlighted in Angew. Chem. Int. Ed. Devising Boron Reagents for Orthogonal

Functionalization through Suzuki-Miyaura Cross-Coupling 2009, 48, 3565-3568.

Highlighted in Angew. Chem. Int. Ed. Controlled Iterative Cross-Coupling: On the

Way to the Automation of Organic Synthesis 2009, 48, 5240-5244.

Highlighted by Steven Ley in Chemtracts Methyliminodiacetic Acid (MIDA)

Boronates:

2007.

Licensed to Sigma-Aldrich (Milwaukee, WI). Worldwide commercial launch of large

collection of MIDA boronates (now > 70 building blocks) on October 7, 2008. This

launch was highlighted by CNN, Forbes, Tech.com, Chemical and Engineering News,

Chemistry World, Genetic Engineering and Biotechnology News, Bio-Medicine,

Pharmasia, and Merck Medicus.

A complete list of commercially available MIDA boronates can be found at:

www.sigmaaldrich.com/mida

See also: http://www.sigmaaldrich.com/chemistry/chemical-synthesis/learning-

center/chemfiles.html

Other reviews and book chapters

3 2

17. P. Wang and M.D. Burke, Diastereoselective Hydroboration and sp-sp Suzuki Coupling:

Application to the Construction of the Amphotericin B Polyol Subunit Boron in the

Americas

XII, June 6-10, 2010, Michigan State University, East Lansing, MI

16. M.D. Burke, The Prospect of Molecular Prosthetics: Small Molecules with Protein-Like

Functions 239 ACS National Meeting, Frontiers in Chemical Biology Symposium, San

Francisco, CA.

15. S.J. Lee and M.D. Burke, A General Platform for Polyene Synthesis Via Iterative Cross-

Coupling 239th ACS National Meeting & Exposition - March 21-25, 2010, San Francisco,

CA.

14. I. Dailey and M.D. Burke, Synthesis of a Universal Polyene Macrolide Building Block

via a

Novel Diastereotopic Group-Selective Lactonization. 239 ACS National Meeting,

Symposium, San Francisco, CA.

13. S.J. Lee and M.D. Burke, A General Platform for Polyene Synthesis Via Iterative

Cross-

Coupling ACS Midwest Regional Meeting, Iowa City, IA, October 23, 2009.

12. M.D. Burke, Synthesis and Study of Small Molecules with Protein-Like Functions 238

ACS

National Meeting, Washington DC, United States, August 16-20, 2009.

11. D.M. Knapp, E.P. Gillis, M.D. Burke, In Situ Release of Boronic Acids from Air

Stable

MIDA Boronates 238 ACS National Meeting, Washington DC, United States, August 16-20,

2009.

10. M.D. Burke, Probing the Amphotericin B Ion Channel via Iterative Cross-Coupling with

MIDA Boronates 237 ACS National Meeting, Salt Lake City, UT, United States, March 22-

28, 2009.

9. E.P. Gillis, M.D. Burke Multistep Synthesis of Complex Boronic Acids from Simple MIDA

Boronates 237 ACS National Meeting, Salt Lake City, UT, United States, March 22-28,

2009.

Martin D. Burke, PhD, MD

8. E.P. Gillis, M.D. Burke Iterative Cross-Coupling: A Simple Strategy for Complex Small

Molecule Synthesis 236 ACS National Meeting, Philadelphia, PA, United States, August 17-

21, 2008.

7. D.S. Palacios, T.M. Anderson, M.D. Burke Oxidation at C(41) is Not Necessary for

Potent

Antifungal Activity in Amphotericin B 236 ACS National Meeting, Philadelphia, PA, United

States, August 17-21, 2008.

6. S.J. Lee, K.C. Gray, J.S. Paek, M.D. Burke. Simple, Efficient, and Modular Syntheses

Polyene Natural Products via Iterative Cross-Coupling 236 ACS National Meeting,

Philadelphia, PA, United States, August 17-21, 2008.

5. M.D. Burke. Molecular Prosthetics: Replicating the Functions of the Molecules of

Life

Enhancing Chemistry Conference. University of Illinois at Urbana-Champaign, Urbana,

Illinois, March 17, 2006.

Invited Presentations

1. March, 2006 Enhancing Chemistry Conference. UIUC, Urbana, IL

Molecular Prosthetics: Replicating the Functions of the Molecules of Life

2. May, 2006 NIH Mentoring Conference, Greenbelt, MD

3. July, 2007 Natural Products Gordon Conference, Tilton, NH

Towards the Total Synthesis of the Channel-Forming Natural Product Amphotericin B

4. July, 2007Sigma-Aldrich Company, Milwaukee, WI

Iterative Cross-Coupling: A Simple and Modular Strategy for Small Molecule Synthesis

5. October, 2007Rigel Pharmaceuticals, San Francisco, CA

6. October, 2007ACS Regional Conference, Milwaukee, WI

The Channel-Forming Natural Product Amphotericin B

7. November, 2007Illinois Wesleyan University, Bloomington, IL

8. January, 2008Abbott Pharmaceuticals, Abbott Park, IL

9. February, 2008Bristol-Myers Squibb, Process Research and Development, New

Brunswick, NJ

10. February, 2008Bristol-Myers Squibb, Drug Discovery, Hopewell, NJ

11. March, 2008 Novartis Pharmaceuticals, San Francisco, CA

12. March, 2008Roche Pharmaceuticals, Palo Alto, CA

13. March, 2008Indiana University at Bloomington, Bloomington, IN

14. April, 2008Pfizer Medicinal Chemistry, St. Louis, MI

15. March, 2008Theravance Pharmaceuticals, San Francisco, CA

Martin D. Burke, PhD, MD

16. May, 2008Merck Research Laboratories, Rahway, NJ

17. June, 2008 Bioorganic Gordon Conference, Andover, NH

Synthesis-Enabled Studies of the Amphotericin B Ion Channel

18. June, 2008 National Science Foundation Annual Workshop on Organic Synthesis and

Natural

Products Chemistry, Minary Center, New Hampshire.

19. August, 2008 Arnold and Mabel Beckman Foundation Symposium for the Beckman Young

Investigator Award, National Academies of Science and Engineering, Irvine, CA

20. October, 2008Bristol-Myers Squibb, Drug Discovery, Hopewell, NJ

21. October, 2008Bristol-Myers Squibb, Drug Discovery, Wallingford, CT

22. October, 2008 University of California at Los Angeles, Los Angeles, CA

23. October, 2008Gothenburg University, Gothenburg, Sweden

24. October, 2008 AstraZeneca, Gothenburg, Sweden

25. October, 2008 Leo Pharmaceuticals, Copenhagen, Denmark

26. October, 2008 AstraZeneca, Stockholm, Sweden

27. October, 2008 Royal Institute of Technology, Stockholm, Sweden

28. October, 2008 Rikshospitalet, Oslow, Norway

29. October, 2008 FAST Conference sponsored by Johnson Mathey, The National

Constitution

Center, Philadelphia, PA Probing the Amphotericin B Ion Channel with Synthetic

Knockouts

30. November, 2008 Novartis Institute for Biomedical Research, Cambridge, MA

31. January, 2009Wayne State University, Detroit, MI

32. January, 2009Hope College, Holland, MI

33. March, 2009Institute for Genomic Biology, University of Illinois, IL

th st

34. March, 2009 237 ACS National Meeting, Special Symposium, Boronate Chemistry in the

Century Sponsored by Frontier Scientific, Salt Lake City, UT

35. March, 2009 University of Pennsylvania, Philadelphia, PA

36. April, 2009UIUC College of Medicine Seminar Series, Carle Hospital and Clinic, IL

37. May, 2009Abbott Pharmaceuticals, Abbott Park, IL

38. May, 2009 University of Chicago, Chicago, IL

39. May, 2009California Institute of Technology, Pasadena, CA

40. May, 2009Princeton University, Bristol-Myers Squibb Lectureship, Princeton, NJ

41. June, 2009 Rising Organic Chemists in Catalysis Meeting, MUnster, Germany

42. June, 2009 Novartis Pharma, Basel, Switzerland

43. July, 2009Merck Research Laboratories, Rahway, NJ

44. July, 2009Schering-Plough, Kenilworth, NJ

45. July, 2009Hoffman-LaRoche, Nutley, NJ

46. July, 2009Lexicon Pharmaceuticals, Princeton, NJ

47. July, 2009Sanofi-Aventis, Bridgewater, NJ

48.

August 2009Eli Lilly, Indianapolis, IN

49. August, 2009 238 ACS National Meeting Young Investigator s Symposium, Washington

D.C.

50. August, 2009Beckman Young Investigator s Symposium, Irvine, CA

51. September, 2009UTSW Medical Center, Dallas, TX

52. September, 2009 Michigan State University, MI

53. October, 2009 Amgen Young Investigator s Award Symposium, Amgen, Thousand Oaks, CA,

The Prospect of Molecular Prosthetics: Small Molecules with Protein-Like Functions

54. October, 2009 University of California Santa Barbara, Santa Barbara, CA

55. October, 2009 AstraZeneca Excellence in Chemistry Award, Wilmington, DE, The

Prospect of

Molecular Prosthetics: Small Molecules with Protein-Like Functions

56. October, 2009 Bristol-Myers Squibb, New Pharma Symposium

57. November, 2009 Howard Hughes Medical Institute Early Career Scientists Meeting,

Janelia

Farm Research Campus, Chevy Chase, MD

Martin D. Burke, PhD, MD

58. February, 2010 Frontiers in Chemistry Symposium, Scripps Research Institute, La

Jolla, CA

59. March, 2010 239 ACS National Meeting, Frontiers in Chemical Biology Symposium,

San

Francisco, CA, Prospect of Molecular Prosthetics: Small Molecules with Protein-Like

Functions

60. March, 2010 ACS/Chem. Eng. News International Webinar, MIDA Boronate Building

Blocks:

Towards a General Platform for Small Molecule Synthesis broadcast live from the 239 ACS

National Meeting, San Francisco, CA: http://pubs.acs.org/cen/webinar/webinar-sigma.html

61. March, 2010 University of Wisconsin-Madison, WI

62. March, 2010Cornell University, NY

63. March, 2010Boston College, Boston, MA

64. April, 2010 University of California at Berkeley, Novartis Lectureship, Berkeley,

65. May, 2010Hoffman-LaRoche, Nutley, NJ

66. May, 2010AstraZeneca Pharmaceuticals, Boston, MA

67. May, 2010Boehringer-Ingelheim Pharmaceuticals, Ridgefield, CT

68. May, 2010BASF, Evans City, PA

69. May, 2010 Synthesis and Applications of Boron Compounds Symposium, 93 Canadian

Society

for Chemistry Conference, Toronto, Canada

70. June, 2010 ACS/Chem. Eng. News International Webinar, MIDA Boronate Building

Blocks:

Towards a General Platform for Small Molecule Synthesis broadcast live from University

of Illinois

at Urbana-Champaign

71. June, 2010 High Throughput Chemistry and Chemical Biology Gordon Research

Conference,

Les Diablerets, Switzerland

72. June, 2010 Balticum Organicum Syntheticum (BOS 10), Riga, Latvia

73. July, 2010 Natural Products Gordon Research Conference, Tilton, NH

74. August, 2010Sigma-Aldrich, Milwaukee, WI

75. August, 2010Merck Research Laboratories, Boston, MA

76. September, 2010 University of Illinois at Urbana-Champaign, Urbana, IL

77. September, 2010Harvard University, Bristol-Myers Squibb Lectureship, Cambridge, MA

78. September, 2010Yale University, New Haven, CT

79. January, 2011UIUC Department of Biochemistry, Urbana, IL

80. February, 2011Columbia University, New York, New York

81. March, 2011 University of Pennsylvania Department of Biochemistry and Molecular

Biophysics,

Philadelphia, PA

82. April, 2011 University of Minnesota, College of Pharmacy, Minneapolis, MN

83. April, 2011Bristol-Myers Squibb Grantee Symposium

Spring, 2011Texas A&M University, College Station, TX

85. July, 2011Organic Reactions and Processes Gordon Research Conference, Smithfield,

86. November, 2011Howard Hughes Medical Institute, Investigators Meeting, Chevy Chase,

87. Spring 2012Eli Lilly Grantee Symposium, Indianapolis, IN

Teaching

Fall 2006 Chem 534: Fundamentals of Complex Molecule Synthesis

- Fall 2008 Teacher Ranked as Excellent and Teacher Ranked as Outstanding

Spring 2007 Chemistry 237: Structure and Synthesis

Teacher Ranked as Excellent

Spring 2006, Chem 536: Introduction to Organic Chemistry Research

Spring 2008

Spring 2009 Chem 437: Advanced Organic Lab

Spring 2010 Chem 436: Organic Chemistry II

Martin D. Burke, PhD, MD

Service

University of Illinois

2005 present Department of Chemistry Graduate Admissions Committee

2005 present Department of Chemistry Graduate Recruiting Committee

2005 present Medical Scholars Program, ad hoc member of Admissions Committee

2005 present Medical Scholars Program, ad hoc member of Recruiting Committee

March, 2006 Keynote speaker, Enhancing Chemistry: A Conference for Chemistry Teachers

Fall, 2006 Pines Travel Award Selection Committee

2005 2006 Coordinator of Organic Registration Exam

Spring, 2007 Department of Pharmacology New Faculty Search Committee

September, 2007 Host of the Marvel Lecture Series

2008 2009 Department of Chemistry New Faculty Search Committee

2007 present Lab Partners High School Chemistry Outreach Program

http://www.scs.illinois.edu/burke/index.php?p=webphotos&Qwd=./photos/Lab%20Partners%20200

8&Qif

Service outside of University of Illinois

June, 2005 present Referee for many scientific journals

June, 2007 Ad hoc member of the National Institutes of Health Synthetic and Biological

Chemistry B Study Section, Washington, D.C.

February, 2008 Panel member for the National Science Foundation Graduate Research

Fellowships Chemistry II Division,

Arlington, VA.

October, 2008Panel member for the National Science Foundation CAREER Awards,

Washington, D.C.

July, 2009 Ad hoc member of the National Institutes of Health Roadmap Initiative Grants

Study Section,

Washington D.C.

Consultantships

Bristol-Myers Squibb, New Jersey and Connecticut, USA

11/08present

Rigel Pharmaceuticals, San Francisco, California, USA

12/07present

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