Medical University
Resume:
Martin D. Burke
Curriculum Vitae
Early Career Scientist phone: 217-***-****
Howard Hughes Medical Institute fax: 217-***-****
Assistant Professor of Chemistry email: abox3h@r.postjobfree.com
University of Illinois at Urbana-Champaign web site: http://www.scs.uiuc.edu/burke/
454 Roger Adams Laboratory
600 South Mathews Ave.
Urbana, IL 61801 Born: Feb. 5, 1976, Westminster, MD
Education
1998-2005 National Institutes of Health Fellow in the Medical Scientist Training Program
Harvard Medical School/Massachusetts Institute of Technology
Division of Health Sciences and Technology: Boston, Massachusetts
Degree awarded: M.D.
1999-2003 Howard Hughes Medical Institutes Predoctoral Fellow
Harvard University, Department of Chemistry and Chemical Biology
Cambridge, Massachusetts, Degree Awarded: Ph.D.
Thesis advisor: Professor Stuart L. Schreiber
1994-1998 Johns Hopkins University, Baltimore, Maryland
Degree Awarded: B.A. Chemistry
Research advisors: Professors Henry Brem and Gary H. Posner
Appointments
August 2005 Assistant Professor, Department of Chemistry
University of Illinois at Urbana-Champaign, Urbana, Illinois
Sept. 2009 Affiliate Faculty, Department of Biochemistry, UIUC
October 2009 Early Career Scientist, Howard Hughes Medical Institute
Awards and honors
2010 Bristol-Myers Squibb Lectureship at Harvard University
2010 Frontiers in Chemistry Lectureship at The Scripps Research Institute
2010 Novartis Lectureship at The University of California Berkeley
2009 Howard Hughes Medical Institute Early Career Scientist
2009 Alfred P. Sloan Foundation Research Fellowship
2009 Bristol-Myers Squibb Unrestricted Grant in Synthetic Organic Chemistry Award
2009 Eli Lilly Grantee Award
2009 AstraZeneca Excellence in Chemistry Award
2009 Amgen Young Investigator Award
2009 Bristol-Myers Squibb Lectureship at Princeton University
2009 Thieme Chemistry Journals Award
2008 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence
2008 Arnold and Mabel Beckman Foundation Young Investigator Award
2008 World s 35 Top Innovators Under 35 Technology Review Magazine
2008 National Science Foundation CAREER Award
2008 Scientist to Watch The Scientist Magazine2007 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence
2006 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence
Martin D. Burke, PhD, MD
2005 ACS Petroleum Research Foundation Type G Award
2005 Camille and Henry Dreyfus New Faculty Award
2005 Henry Asbury Christian Award, Harvard Medical School
2003 National Institutes of Health Medical Scientist Training Program Fellowship
2000 Howard Hughes Medical Institute Predoctoral Fellowship
1998 Hunterian Research Award - Johns Hopkins Department of Neurosurgery
1997 Phi Beta Kappa - Junior Year, Johns Hopkins University
1997 Howard Hughes Undergraduate Research Fellowship - Johns Hopkins University
1997 Provost s Undergraduate Research Award - Johns Hopkins University
1994-1998 Dean s List - Johns Hopkins University
1994-1998 Beneficial Hodson Scholar - Johns Hopkins University
1994-1998 Maryland Distinguished Scholar
Publications http:
Synthesis:
Iterative Suzuki-Miyaura Coupling of B-Protected Haloboronic Acid Building Blocks. J.
Am.
Chem. Soc. 2007, 129, 6716-6717.
Highlighted in Chemical and Engineering News: Masks unveil new synthetic routes
2007, 85, 63-64.
Highlighted in SynFacts 2007, 10, 1007
Highlighted in Synform 2008, 5, 58-59.
Highlighted in Chemistry World February 2008, p. 27.
Reviewed in Accounts of Chemical Research 2008, 41, 1461-1473.
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Martin D. Burke, PhD, MD
Highlighted in Angew. Chem. Int. Ed. Devising Boron Reagents for Orthogonal
Functionalization through Suzuki-Miyaura Cross-Coupling 2009, 48, 3565-3568.
Highlighted in Angew. Chem. Int. Ed. Controlled Iterative Cross-Coupling: On the
Way to the Automation of Organic Synthesis 2009, 48, 5240-5244.
Highlighted by Steven Ley in Chemtracts Methyliminodiacetic Acid (MIDA)
Boronates:
2007.
Licensed to Sigma-Aldrich (Milwaukee, WI). Worldwide commercial launch of large
collection of MIDA boronates (now > 70 building blocks) on October 7, 2008. This
launch was highlighted by CNN, Forbes, Tech.com, Chemical and Engineering News,
Chemistry World, Genetic Engineering and Biotechnology News, Bio-Medicine,
Pharmasia, and Merck Medicus.
A complete list of commercially available MIDA boronates can be found at:
www.sigmaaldrich.com/mida
See also: http://www.sigmaaldrich.com/chemistry/chemical-synthesis/learning-
center/chemfiles.html
Other reviews and book chapters
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17. P. Wang and M.D. Burke, Diastereoselective Hydroboration and sp-sp Suzuki Coupling:
Application to the Construction of the Amphotericin B Polyol Subunit Boron in the
Americas
XII, June 6-10, 2010, Michigan State University, East Lansing, MI
16. M.D. Burke, The Prospect of Molecular Prosthetics: Small Molecules with Protein-Like
th
Functions 239 ACS National Meeting, Frontiers in Chemical Biology Symposium, San
Francisco, CA.
15. S.J. Lee and M.D. Burke, A General Platform for Polyene Synthesis Via Iterative Cross-
Coupling 239th ACS National Meeting & Exposition - March 21-25, 2010, San Francisco,
CA.
14. I. Dailey and M.D. Burke, Synthesis of a Universal Polyene Macrolide Building Block
via a
th
Novel Diastereotopic Group-Selective Lactonization. 239 ACS National Meeting,
Symposium, San Francisco, CA.
13. S.J. Lee and M.D. Burke, A General Platform for Polyene Synthesis Via Iterative
Cross-
Coupling ACS Midwest Regional Meeting, Iowa City, IA, October 23, 2009.
th
12. M.D. Burke, Synthesis and Study of Small Molecules with Protein-Like Functions 238
ACS
National Meeting, Washington DC, United States, August 16-20, 2009.
11. D.M. Knapp, E.P. Gillis, M.D. Burke, In Situ Release of Boronic Acids from Air
Stable
th
MIDA Boronates 238 ACS National Meeting, Washington DC, United States, August 16-20,
2009.
10. M.D. Burke, Probing the Amphotericin B Ion Channel via Iterative Cross-Coupling with
th
MIDA Boronates 237 ACS National Meeting, Salt Lake City, UT, United States, March 22-
28, 2009.
9. E.P. Gillis, M.D. Burke Multistep Synthesis of Complex Boronic Acids from Simple MIDA
th
Boronates 237 ACS National Meeting, Salt Lake City, UT, United States, March 22-28,
2009.
5
Martin D. Burke, PhD, MD
8. E.P. Gillis, M.D. Burke Iterative Cross-Coupling: A Simple Strategy for Complex Small
th
Molecule Synthesis 236 ACS National Meeting, Philadelphia, PA, United States, August 17-
21, 2008.
7. D.S. Palacios, T.M. Anderson, M.D. Burke Oxidation at C(41) is Not Necessary for
Potent
th
Antifungal Activity in Amphotericin B 236 ACS National Meeting, Philadelphia, PA, United
States, August 17-21, 2008.
6. S.J. Lee, K.C. Gray, J.S. Paek, M.D. Burke. Simple, Efficient, and Modular Syntheses
of
th
Polyene Natural Products via Iterative Cross-Coupling 236 ACS National Meeting,
Philadelphia, PA, United States, August 17-21, 2008.
5. M.D. Burke. Molecular Prosthetics: Replicating the Functions of the Molecules of
Life
Enhancing Chemistry Conference. University of Illinois at Urbana-Champaign, Urbana,
Illinois, March 17, 2006.
Invited Presentations
1. March, 2006 Enhancing Chemistry Conference. UIUC, Urbana, IL
Molecular Prosthetics: Replicating the Functions of the Molecules of Life
2. May, 2006 NIH Mentoring Conference, Greenbelt, MD
3. July, 2007 Natural Products Gordon Conference, Tilton, NH
Towards the Total Synthesis of the Channel-Forming Natural Product Amphotericin B
4. July, 2007Sigma-Aldrich Company, Milwaukee, WI
Iterative Cross-Coupling: A Simple and Modular Strategy for Small Molecule Synthesis
5. October, 2007Rigel Pharmaceuticals, San Francisco, CA
6. October, 2007ACS Regional Conference, Milwaukee, WI
The Channel-Forming Natural Product Amphotericin B
7. November, 2007Illinois Wesleyan University, Bloomington, IL
8. January, 2008Abbott Pharmaceuticals, Abbott Park, IL
9. February, 2008Bristol-Myers Squibb, Process Research and Development, New
Brunswick, NJ
10. February, 2008Bristol-Myers Squibb, Drug Discovery, Hopewell, NJ
11. March, 2008 Novartis Pharmaceuticals, San Francisco, CA
12. March, 2008Roche Pharmaceuticals, Palo Alto, CA
13. March, 2008Indiana University at Bloomington, Bloomington, IN
14. April, 2008Pfizer Medicinal Chemistry, St. Louis, MI
15. March, 2008Theravance Pharmaceuticals, San Francisco, CA
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Martin D. Burke, PhD, MD
16. May, 2008Merck Research Laboratories, Rahway, NJ
17. June, 2008 Bioorganic Gordon Conference, Andover, NH
Synthesis-Enabled Studies of the Amphotericin B Ion Channel
18. June, 2008 National Science Foundation Annual Workshop on Organic Synthesis and
Natural
Products Chemistry, Minary Center, New Hampshire.
19. August, 2008 Arnold and Mabel Beckman Foundation Symposium for the Beckman Young
Investigator Award, National Academies of Science and Engineering, Irvine, CA
20. October, 2008Bristol-Myers Squibb, Drug Discovery, Hopewell, NJ
21. October, 2008Bristol-Myers Squibb, Drug Discovery, Wallingford, CT
22. October, 2008 University of California at Los Angeles, Los Angeles, CA
23. October, 2008Gothenburg University, Gothenburg, Sweden
24. October, 2008 AstraZeneca, Gothenburg, Sweden
25. October, 2008 Leo Pharmaceuticals, Copenhagen, Denmark
26. October, 2008 AstraZeneca, Stockholm, Sweden
27. October, 2008 Royal Institute of Technology, Stockholm, Sweden
28. October, 2008 Rikshospitalet, Oslow, Norway
29. October, 2008 FAST Conference sponsored by Johnson Mathey, The National
Constitution
Center, Philadelphia, PA Probing the Amphotericin B Ion Channel with Synthetic
Knockouts
30. November, 2008 Novartis Institute for Biomedical Research, Cambridge, MA
31. January, 2009Wayne State University, Detroit, MI
32. January, 2009Hope College, Holland, MI
33. March, 2009Institute for Genomic Biology, University of Illinois, IL
th st
34. March, 2009 237 ACS National Meeting, Special Symposium, Boronate Chemistry in the
21
Century Sponsored by Frontier Scientific, Salt Lake City, UT
35. March, 2009 University of Pennsylvania, Philadelphia, PA
36. April, 2009UIUC College of Medicine Seminar Series, Carle Hospital and Clinic, IL
37. May, 2009Abbott Pharmaceuticals, Abbott Park, IL
38. May, 2009 University of Chicago, Chicago, IL
39. May, 2009California Institute of Technology, Pasadena, CA
40. May, 2009Princeton University, Bristol-Myers Squibb Lectureship, Princeton, NJ
41. June, 2009 Rising Organic Chemists in Catalysis Meeting, MUnster, Germany
42. June, 2009 Novartis Pharma, Basel, Switzerland
43. July, 2009Merck Research Laboratories, Rahway, NJ
44. July, 2009Schering-Plough, Kenilworth, NJ
45. July, 2009Hoffman-LaRoche, Nutley, NJ
46. July, 2009Lexicon Pharmaceuticals, Princeton, NJ
47. July, 2009Sanofi-Aventis, Bridgewater, NJ
48.
August 2009Eli Lilly, Indianapolis, IN
th
49. August, 2009 238 ACS National Meeting Young Investigator s Symposium, Washington
D.C.
50. August, 2009Beckman Young Investigator s Symposium, Irvine, CA
51. September, 2009UTSW Medical Center, Dallas, TX
52. September, 2009 Michigan State University, MI
53. October, 2009 Amgen Young Investigator s Award Symposium, Amgen, Thousand Oaks, CA,
The Prospect of Molecular Prosthetics: Small Molecules with Protein-Like Functions
54. October, 2009 University of California Santa Barbara, Santa Barbara, CA
55. October, 2009 AstraZeneca Excellence in Chemistry Award, Wilmington, DE, The
Prospect of
Molecular Prosthetics: Small Molecules with Protein-Like Functions
56. October, 2009 Bristol-Myers Squibb, New Pharma Symposium
57. November, 2009 Howard Hughes Medical Institute Early Career Scientists Meeting,
Janelia
Farm Research Campus, Chevy Chase, MD
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Martin D. Burke, PhD, MD
58. February, 2010 Frontiers in Chemistry Symposium, Scripps Research Institute, La
Jolla, CA
th
59. March, 2010 239 ACS National Meeting, Frontiers in Chemical Biology Symposium,
San
Francisco, CA, Prospect of Molecular Prosthetics: Small Molecules with Protein-Like
Functions
60. March, 2010 ACS/Chem. Eng. News International Webinar, MIDA Boronate Building
Blocks:
th
Towards a General Platform for Small Molecule Synthesis broadcast live from the 239 ACS
National Meeting, San Francisco, CA: http://pubs.acs.org/cen/webinar/webinar-sigma.html
61. March, 2010 University of Wisconsin-Madison, WI
62. March, 2010Cornell University, NY
63. March, 2010Boston College, Boston, MA
64. April, 2010 University of California at Berkeley, Novartis Lectureship, Berkeley,
CA
65. May, 2010Hoffman-LaRoche, Nutley, NJ
66. May, 2010AstraZeneca Pharmaceuticals, Boston, MA
67. May, 2010Boehringer-Ingelheim Pharmaceuticals, Ridgefield, CT
68. May, 2010BASF, Evans City, PA
rd
69. May, 2010 Synthesis and Applications of Boron Compounds Symposium, 93 Canadian
Society
for Chemistry Conference, Toronto, Canada
70. June, 2010 ACS/Chem. Eng. News International Webinar, MIDA Boronate Building
Blocks:
Towards a General Platform for Small Molecule Synthesis broadcast live from University
of Illinois
at Urbana-Champaign
71. June, 2010 High Throughput Chemistry and Chemical Biology Gordon Research
Conference,
Les Diablerets, Switzerland
72. June, 2010 Balticum Organicum Syntheticum (BOS 10), Riga, Latvia
73. July, 2010 Natural Products Gordon Research Conference, Tilton, NH
74. August, 2010Sigma-Aldrich, Milwaukee, WI
75. August, 2010Merck Research Laboratories, Boston, MA
76. September, 2010 University of Illinois at Urbana-Champaign, Urbana, IL
77. September, 2010Harvard University, Bristol-Myers Squibb Lectureship, Cambridge, MA
78. September, 2010Yale University, New Haven, CT
79. January, 2011UIUC Department of Biochemistry, Urbana, IL
80. February, 2011Columbia University, New York, New York
81. March, 2011 University of Pennsylvania Department of Biochemistry and Molecular
Biophysics,
Philadelphia, PA
82. April, 2011 University of Minnesota, College of Pharmacy, Minneapolis, MN
83. April, 2011Bristol-Myers Squibb Grantee Symposium
84
.
Spring, 2011Texas A&M University, College Station, TX
85. July, 2011Organic Reactions and Processes Gordon Research Conference, Smithfield,
RI
86. November, 2011Howard Hughes Medical Institute, Investigators Meeting, Chevy Chase,
MD
87. Spring 2012Eli Lilly Grantee Symposium, Indianapolis, IN
Teaching
Fall 2006 Chem 534: Fundamentals of Complex Molecule Synthesis
- Fall 2008 Teacher Ranked as Excellent and Teacher Ranked as Outstanding
Spring 2007 Chemistry 237: Structure and Synthesis
Teacher Ranked as Excellent
Spring 2006, Chem 536: Introduction to Organic Chemistry Research
Spring 2008
Spring 2009 Chem 437: Advanced Organic Lab
Spring 2010 Chem 436: Organic Chemistry II
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Martin D. Burke, PhD, MD
Service
University of Illinois
2005 present Department of Chemistry Graduate Admissions Committee
2005 present Department of Chemistry Graduate Recruiting Committee
2005 present Medical Scholars Program, ad hoc member of Admissions Committee
2005 present Medical Scholars Program, ad hoc member of Recruiting Committee
March, 2006 Keynote speaker, Enhancing Chemistry: A Conference for Chemistry Teachers
Fall, 2006 Pines Travel Award Selection Committee
2005 2006 Coordinator of Organic Registration Exam
Spring, 2007 Department of Pharmacology New Faculty Search Committee
September, 2007 Host of the Marvel Lecture Series
2008 2009 Department of Chemistry New Faculty Search Committee
2007 present Lab Partners High School Chemistry Outreach Program
http://www.scs.illinois.edu/burke/index.php?p=webphotos&Qwd=./photos/Lab%20Partners%20200
8&Qif
Service outside of University of Illinois
June, 2005 present Referee for many scientific journals
June, 2007 Ad hoc member of the National Institutes of Health Synthetic and Biological
Chemistry B Study Section, Washington, D.C.
February, 2008 Panel member for the National Science Foundation Graduate Research
Fellowships Chemistry II Division,
Arlington, VA.
October, 2008Panel member for the National Science Foundation CAREER Awards,
Washington, D.C.
July, 2009 Ad hoc member of the National Institutes of Health Roadmap Initiative Grants
Study Section,
Washington D.C.
Consultantships
Bristol-Myers Squibb, New Jersey and Connecticut, USA
11/08present
Rigel Pharmaceuticals, San Francisco, California, USA
12/07present
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