CURRICULUM VITAE
D. David Smith, Ph.D.
Associate Professor of Biomedical Sciences
Department of Biomedical Sciences
Creighton University School of Medicine
Omaha, Nebraska 68178-0405
******@*********.***
Education
1980 - 1983 B.Sc. (Hons.) in chemistry, Imperial College of Science & Technology, London,
England.
1983 1984 Postgraduate student, University of Manchester Institute of Science &
Technology,
England, Organic Chemistry.
1984 1986 Postgraduate student, The University of Edinburgh, Scotland, Organic
Chemistry.
Ph.D., thesis titled The Use of Phosphorus-Based Reagents in the Synthesis of
Substance P Analogues, advisor; Prof. Robert Ramage.
Academic Appointments
Postdoctoral Fellow, Department of Chemistry, University of Arizona, Tucson AZ. 1986-
1989. Advisor
:
Professor Victor J. Hruby.
Assistant Professor, Department of Biomedical Sciences, Creighton University, Omaha, NE.
1989- 1995.
(Received tenure July 1, 1994).
Associate Professor, Department of Biomedical Sciences, Creighton University, Omaha, NE.
1995 -
present
.
Associate Professor (Secondary Appointment), Department of Pharmacology, Creighton
University,
Omaha, NE. 1996 - present
.
Professional Activities and Awards
Member of the Royal Society of Chemistry since 1982.
Member of the American Chemical Society since 1987.
Member of the American Peptide Society since 1990.
Member of the Nebraska Academy of Sciences 2004.
Associate Member of the European Peptide Society.
Young Investigator Award, Creighton University School of Medicine, 1994.
NIH FIRST Award, 1994-1998.
Research Volunteer of the Year Award, American Heart Association-Nebraska Affiliate,
1997.
27 February 2012
Grants
Health Future Foundation, $9,962
October 1, 1989 - September 30, 1990
"Structure-activity studies of CGRP"
Principal Investigator
Pharmaceutical Manufacturers Association Foundation, $20,000
January 1, 1990 - December 31, 1991
"Structure activity of the disulfide bridge of calcitonin gene-related peptide"
Principal InvestigatorNebraska Affiliate of the American Heart Association, $19,932
July 1, 1991 to June 31, 1992
"Study the actions of N-terminal fragments of CGRP on cardiac and vascular muscle"
Principal InvestigatorHealth Future Foundation, $9,000
October 1, 1991 to September 31, 1992 - Extended to June 30, 1993
"Study rate of racemization during fragment couplings in solid phase peptide synthesis"
Principal InvestigatorState of Nebraska, Department of Health, $526,205
July 1, 1994 to June 30, 1998
Peptide Chemistry Core Facility
Prinicipal DirectorState of Nebraska, Department of Health, $172,404
July 1, 1994 to June 30, 1997
The role of CGRP in smoking related diseases
Principal Investigator
National Science Foundation, $250,600
October 1, 1994
"Acquisition of a 300 MHz NMR spectrometer"
Co-Investigator. Martin R. Hulce, Principal Investigator
State of Nebraska, Department of Health, $76,592
July 1, 1997 to June 30, 1998
CGRP analogue design, airway obstruction and smoking
Principal Investigator
R29-HL51131 National Heart, Lung and Blood Institute - NIH, $274,364
January 1, 1994 to December 31, 1998.
"Structure function studies of human-a-CGRP"
Principal Investigator.
National Kidney Foundation,
Nebraska Division, $5,000
July 1, 1999 to June 30, 2000Immunological Analysis of a Unique Sodium/Hydrogen Exchange Isoform
#
Co-Investigator. David Petzel, Principal Investigator
Intesco Laboratories, $45,000
January 1, 2001 to August 15, 2002
Purification, Structural Characterization of Active Components of the Coherin Extract
Principal Investigator.
1R01DK055830-01A2 - NIH, $750,000
August 1, 2001 to July 31, 2006.
"Regulation of Food Intake and Body Weight by Amylin"
Co-Investigator.
Daichii Pharmaceutical (No Identifying Number)
July 1, 2005September 30, 2006
Pharmacodynamics of DX-619 against Methicillin-Resistant Staphylococcus aureus in an In
Vitro Pharmacokinetic Model: Evaluation of impact of Cmax/MIC and AUC/MIC ratios and
%Time above MIC on Antibacterial Activity.
Co-Investigator. Philip Lister, Principal Investigator.
Daichii Pharmaceutical (No Identifying Number)
May 01, 2007September 30, 2008
Pharmacodynamics of DX-619 against Methicillin-Resistant Staphylococcus aureus in an In
Vitro Pharmacokinetic Model: Evaluation of impact of Cmax/MIC and AUC/MIC ratios and
%Time above MIC on Antibacterial Activity.
Co-Investigator. Philip Lister, Principal Investigator.
DHHS, State of Nebraska (LB506 2009-06
), $39,816
July 1, 2008June 30, 2009
Birth Defects: Nicotine and Neurocristopathies
Co-Investigator. Philip Brauer, Principal Investigator
DHHS, State of Nebraska (LB595) $79,088
Cancer and Smoking Research Development,
July1, 2009June 30, 2011Congenital Neurocristopathies and Nicotine.
Co-Investigator. Philip Brauer, Principal Investigator
NIH-NINDS $1,525,249
Member of the Great America 5E peer review committee of the American Heart Association
(1999-2001).
Member of the Molecular Signalling II study section of the American Heart Association
(2002-
2003).
Publications