Manager Manufacturing

PAUL D. COLLINS

* ********* ****** *********, ** 01876 (c) 401-***-**** ***********@***.***

Professional Profile

Manufacturing Operations Engineering

Strategic manufacturing manager with successful experience in improving productivity and

operations practices for companies in the Medical Device, Pharmaceutical, and Biotechnology

industries. Expertise in building and directing diverse cross-functional teams in achieving

crucial company objectives of increased productivity. Highly skilled in developing process

improvements and budget planning initiatives which increase profitability and reduce costs.

Career Highlights

Increased productivity by reviewing and revising processes, standard operating

•

procedures (SOP), and good manufacturing practices (GMP) documentation. (Amgen,

Inc.)

Generated $650K in annual savings by leading engineering studies and reducing process

•

waste. (Schering Plough)

Saved an additional $220K each year by optimizing and validating a liquid-liquid

•

extraction column to recover used Freon. (Schering Plough)

Transferred a newly FDA approved product line to manufacturing, by overseeing

•

capacity planning and supervising scale-up of bulk raw material processes. (Davol)

Designed and validated a new batching vessel, resulting in annual savings of $300K.

•

(Anika Therapeutics)

Core Competencies

Project Management Process Development Team Leadership

Engineering Budget Management Manufacturing

Strategic Planning Operations Product Development

Professional Experience

Xcellerex, Inc. 2008 to 2009

$10 M biotechnology contract manufacturing company.

Manufacturing Manager

Managed downstream purification processes technical transfer and

manufacturing to provide outstanding customer support.

• Transferred and scaled up protein purification processes including

equipment specification and purchase, raw materials specification

and purchase.

• Designed a computer based training recall and tracking system.

• Managed calibration and preventative maintenance for all of

manufacturing.

Amgen, Inc. 2007 to 2008

$14B leading human therapeutics company in the biotechnology industry.

Manufacturing Manager

Directed manufacturing practices to drive exceptional budget control and

superior maintenance, operational, and production processes.

• Increased productivity by reviewing and revising processes, standard

operating procedures (SOP), and good manufacturing practices

(GMP) documentation.

• Managed the team through impending layoffs while maintaining

productivity and exceptional quality levels.

Schering Plough 2002 to 2007

$10B Worldwide pharmaceutical company.

Aerosol Manufacturing Manager

Oversaw all production planning, including safety, maintenance, and process

improvement.

• Produced $650K in savings by leading engineering studies and

reducing process waste.

• Saved an additional $220K each year by optimizing and validating a

liquid-liquid extraction column to recover used Freon.

Hyaluron, Inc. 2000 to 2001

Start up contract manufacturer of prefilled Hyaluronic Acid syringes and

vials.

Engineering Manager

Responsible for the development and validation of customer products and

facilities.

• Developed and scaled up a unique manufacturing process to

efficiently extract and purify Hyaluronic Acid from rooster combs.

• Successfully designed and purchased a reactor system to enable

simultaneous mixing and sterilization of a shear sensitive viscous gel.

Davol 1999 to 2000

$2B Subsidiary of CR Bard Inc manufactures and develops microfibular

collagen hemostats.

Senior Manufacturing Supervisor

Responsible for manufacturing, filling, and packaging of all product lines.

• Transferred a newly FDA approved product line to manufacturing,

by overseeing capacity planning and supervising scale-up of bulk raw

material processes.

• Developed plant wide calibration and PM recall system, resulting in

improved compliance and efficiency of operation.

Anika Therapeutics

1997 to 1999

Company specializing in the development of medical devices based on

Hyaluronic Acid.

Engineering Manager

Validated equipment and processes for developers / marketers of medical

devices and pharmaceuticals based on Hyaluronic Acid innovations.

• Designed a new formulation mixing vessel, leading to an annual

savings of $300K.

• Implemented and validated a filtration train to replace an

ultracentrifugation step, reducing cycle time by 75%, creating

significant annual savings.

Waters Corporation

1988 to 1997

Supplier of HPLC systems for environmental testing, pharmaceutical, and

chemical industries.

Bulk Synthesis Manager

Coordinated manufacturing of 80 chromatographic bulk materials and high-

purity mobile phases.

• Transferred a product family from R&D to manufacturing, leading to

increased sales.

• Improved productivity by formulating a new compensation program,

which rewarded employees for successful of cross-training to acquire

new skills.

Education & Professional Development

MBA University of Rhode Island

BS, Chemical Engineering University of Rhode Island

Courses & Certifications: Six Sigma Black Belt

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