Office Research

Jeffrey L. Vaughn, PhD, Esq.

********@***.***

*** ****** ****** • Newtonville, MA 02460 • 617-***-****

Education

Suffolk University Law School, Evening Division, Boston, MA J.D., January, 2009

State University of New York at Albany, Albany, NY Ph.D., July 2000

“Molecular Mechanistic Model for the DNA-Binding Domain of the Bacillus subtilis

Transition-State Regulatory Protein AbrB by Nuclear Magnetic Resonance Spectroscopy”

• Research focused on molecular biochemistry and biophysical analysis of protein structure

and function, instrumentation and alternative approaches to analyzing protein function

University of Illinois, Chicago, IL B.S., July 1993

• NIH Undergraduate Research Fellowships (1989-91), Undergraduate Research Associate

(1991-1993), Undergraduate Research Travel Award, 1992

Professional Licenses

Massachusetts State Bar June, 2009

Registered to Practice before United States Patent and Trademark Office

November, 2005

Experience

Law Office of Paula Berg, Esq., Newton MA July2009-current

Attorney, Part-time Independent Contractor

Joule Biotechnologies, Inc., Cambridge, MA

Patent Agent Internship June, 2008 - Jan 2009

• Developed corporate IP portfolio through drafting 25+ patents and analyzing patentability

and freedom to operate for metabolic synthesis of biofuels

Repligen Corporation, Waltham, MA

Technology Specialist, Independent Contractor Jan, 2008 - Dec 2008

• Developed corporate IP portfolio through analyzing patentability and freedom to operate

for small organic molecule pharmaceuticals and macromolecular imaging compounds

Forte RTS, Ledyard, CT

Patent Agent, Independent Contractor Summer, 2006

• Drafted provisional patent for a novel platform technology enabling easy manufacture of

carbon composite spars, support structures, booms and masts

MicroStealth Technologies, Beverly, MA

Co-Founder, Scientist 2002 – 2003

• Managed scientific and proprietary operations for a patented macromolecular technology

targeting antibiotic-resistant infections

• Drafted technical documents and SBIR, STTR and DARPA applications

Indiana University, Dept. of Chemistry, Bloomington, IN

Post-Doctoral Research Fellow 2000-2002

• Employed high-field nuclear magnetic resonance to measure protein stability

• Characterized enzyme active sites by correlating dynamic motions to kinetic and

thermodynamic parameters and evaluating ligand binding kinetics

• Collaborated with other researchers on biophysical analysis of a variety of research

programs

• Peer reviewed for Cellular Biochemistry and Biophysics Journal

Publications

Benson, L.M., J.L. Vaughn, M.A. Strauch, B.G. Bobay, R. Thompson, S. Naylor and J. Cavanagh (2002).

Macromolecular Assembly of the Transition-State Regulator AbrB in its Unbound and Complexed States

Probed by Micro-Electrospray Ionization Mass Spectrometry. Anal. Biochem. 306, 222-227.

Sharrow, S.D., J.L. Vaughn, L. Zidek, M.V. Novotny and M.J. Stone. Pheromone Binding by Polymorphic

Mouse Major Urinary Proteins. Prot. Sci. 11(9), 2247-2256.

Vaughn, J.L., C. Bracken, V. Feher and J. Cavanagh. (2001) The DNA-Binding Domain in the Bacillus

subtilis Transition-State Regulator AbrB Employs Significant Motion for Promiscuous DNA Recognition.

J. Mol. Biol. 305 (3), 429-439.

Vaughn, J.L., V. Feher, S. Naylor, M.A. Strauch and J. Cavanagh. (2000). Solution Structure of the Novel

DNA-Binding Domain, Macromolecular Assembly and Model of Genetic Regulation for the Bacillus

subtilis Transition State Regulator AbrB. Nature: Structural Biology 7(12), 1139-1146.

Qu., K, J.L.Vaughn, A. Seinkiewicz, C.P. Scholes and J.S. Fetrow (1997). Kinetics and Motional

Dynamics of Spin-Labeled Yeast Iso-1-cytochrome c. 1. Stopped-Flow Electron Paramagnetic Resonance

as a Probe for Protein Folding/Unfolding of the C-terminal Helix Spin-Labeled at Cysteine 102.

Biochemistry, 36, 2884-2897.

Cracraft, J., J. Feinstein, J.L. Vaughn, K. Helm-Bychowski. (1998). Sorting out Tigers (Panthera tigris):

Mitochondrial Sequences, Nuclear Inserts, Systematics, and Conservation Genetics. Animal Conservation

1:139-150.

Ashley, M.V., J.L. Vaughn. (1995). Owl Monkeys, Genus Aotus, are Highly Divergent in Mitochondrial

Cytochrome c Oxidase (COII) Sequences. Int. J. Prim. 16:793-806

Professional Associations

Boston Patent Law Association

Massachusetts Bar Association

American Intellectual Property Law Association

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