Xiaohan Cai
**** ***** **. ***. **** Cleveland OH 44114
abnnji@r.postjobfree.com
Summary
• Master’s degree in analytical chemistry
• Strong analytical skills with LC-MS, mass spectrometry for small molecular
quantification and protein characterization; 2+ years experience with HPLC
• Hands on experience with protein essays including SDS-PAGE, western blotting and wet
chemistry skills
Education
Cleveland State University, Cleveland, Ohio 2007-
Master of Science Degree in Chemistry; expected in fall of 2009, GPA: 3.90
Huazhong University of Science & Technology, Wuhan, China 2006
Bachelor of Science Degree in Pharmacy, GPA: 3.40
Professional Experience
Research Assistant, Dept. of Chemistry, Cleveland State University 2007-
Project: Analysis of bile acids composition for inflammatory bowel disease using LC-MS
(collaborating with Cleveland Clinic, Center for Inflammatory Bowel Disease)
• Developed and validated a LC-ESI-MS method for bile acids quantification
• Extracted bile acids from intestinal fluid by liquid-liquid extraction and solid phase
extraction methods
• Applied this method for the quantification of potential biomarker of Inflammatory Bowel
Disease in clinical samples
• Maintained and calibrated a triple quadruple mass spectrometer and Waters HPLC
Project: Proteomics profiling for biomarker discovery of ovarian cancer
• Isolated low molecular weight peptides from human serum by protein precipitation and
characterized the LMW peptides by SDS-PAGE
• Performed in-gel and in solution trypsin digestion for LMW proteins and LC-MS analysis
for protein identification
Analytical Chemist Intern, Shanghai Jiaotong Biopharmaceutical Lab Inc. China 2006-2007
• Employed HPLC to monitor the in-vitro release of therapeutic protein drug from polymer
based microspheres under the GLP environment
• Managed the purchase orders and troubleshoot basic problems of lab instruments
Teaching Assistant, Dept. of Chemistry, Cleveland State University 2007-
• Taught wet chemistry and analytical techniques in the General Chemistry Lab
Honors and Awards
• Teaching Assistantship for graduate study in Cleveland State University 2007-
• Excellent graduated student award of Huazhong University of Sci. & Tech. 2006
Publications
Zhang CL, Cai XH, Xiang M. A study of immune tolerance induced by subcutaneous administer-
ation of autoantigen insulin in mice with IDDM. Herald of Medicine 2006; 25(6):495-498