Thomas Chi Ngai Ng, Ph.D.
Home: +1-301-***-****
Derwood, MD 20855
Mobile: +1-301-***-****
E-mail: *******@*****.***
Highlights of Qualifications
. Substantial client interaction and business development experience,
including program management/project management responsibilities
. Managed multiple biotech and pharmaceutical clients on multi-million
dollar contracts simultaneously
. Detail-oriented with excellent organizational and communication skills
. Supervised multiple technical staff
. Over 10 years biotech industry experience and over 20 years scientific
experience
. Strong understanding of the drug discovery and development process
. Broad expertise with molecular, cellular and immunological techniques
. Familiar with Macintosh and Windows operating systems
Professional Experience
2007-2009 ExonHit Therapeutics, Inc. 217 Perry Parkway, Building #5,
Gaithersburg, MD 20877
2007-2009 Director of Market & Business Development, Molecular
Diagnostics & Genomic Services
. Managed all marketing, sales and business development (out-
licensing) activities for SpliceArray (genomic services)
business world-wide including P&L responsibilities and laying
the groundwork for the future molecular diagnostic service
business
. Increased SpliceArray FY07 revenues 20% over FY06 and
increased FY08 sales 20% over FY07
. Negotiated and signed Master Service Agreements (MSA) with
three major pharmaceutical/biotechnology clients
. Established and managed two channel partnerships for
SpliceArray business, one in Canada and the other in the US
Mid-West regions
. Closed company's first SpliceArray deals in the Asia Pacific
region
. Develop and implement marketing plans to target
pharmaceutical and biotechnology accounts including key
applications such as target discovery & validation and
biomarker discovery & development (translational medicine)
. Develop SpliceArray marketing brand by creating unified
message via print & online campaigns as well as exhibit booth
design for industry trade shows
. Recruit and supervise sales and application support staff
2005-2007 Gene Logic Inc. 50 West Watkins Mill Road, Gaithersburg, MD
20878
2006-2007 Senior Manager, Genomics Services
. Responsible for alliance management of strategic
relationships with clinical accrual sites and genomics
services clients
. Manage biorepository budget including supervision of Program
Manager staff
. Provide technical/scientific, costing and pricing support for
genomics services, including responding to RFIs and RFPs
. Support introduction of new technologies for the genomics
services business
2005-2006 Business Development Manager, Asia Pacific & Mid-Atlantic
. Out-licensed genomics & toxicogenomics databases and services
solutions to pharmaceutical, biotechnology and research
organizations in the APAC region for target discovery and
validation, biomarker applications, lead optimization and
clinical genomics applications via a distributor relationship
in Japan and direct sales in the ROW
. As part of the APAC team, closed over $3.3M in business
during first six months, including personally closing deals
with two new customers from countries new to Gene Logic's
client base
. Worked on more than $3.0M of clinical genomics deals to help
expand Gene Logic's emerging presence in that market
. Additionally, worked on more than $5.0M worth of deals
covering the rest of Gene Logic's genomics offerings
. Expanded Gene Logic's business into new APAC countries such
as China, Taiwan, Korea and Singapore by working with State,
Federal and private organizations
. Led Gene Logic's initial market exploration of China by
working with the above mentioned agencies to set up and meet
with key organizations in China that may be potential
customers or partners for Gene Logic, including being
nominated and receiving an internal Gene Logic service award
. Through marketing and business development efforts, expanded
Gene Logic's business into the previously untapped market of
US subsidiaries of Japanese pharmaceutical companies
2001-2004 Celera Genomics Corporation 45 West Gude Drive, Rockville, MD
20850
2002-2004 Client Program Manager, Commercial Development
. Managed all aspects of the client relationship for a number
of US and international pharmaceutical and biotech customers
as their main point of contact to interface with internal
groups such as product development/support, finance, legal,
contracts, and sales & marketing
. Communicated on a regular basis with clients for building a
client relationship
. Maintained a hard copy "binder" for recording background and
all client interactions as well as electronic copies of files
in a protected directory
. Working with a Scientific Lead, visited client sites and met
with appropriate personnel to gather feedback and
intelligence on products and services
. Initiated a number of new sales opportunities with various
pharmaceutical and biotech companies, including closing two
deals with the first new pharmaceutical clients in over 18
months
. Facilitated a renewal deal for a pharmaceutical client
2001-2002 Senior Scientist, Biologics
. Established a program for high-throughput gene expression
profiling for validation of potential anticancer drug targets
using TaqMan technology; Develop assay format, SOPs, and
integration into LIMS
1999-2001 BioReliance Corporation 14920 Broschart Road, Rockville, MD
20850
Scientist, Research and Development
. Developed GLP PCR and Q-PCR assays for the detection of
bovine polyomavirus, human polyomavirus (BKV and JCV),
reovirus, cache valley virus, STLV-I, adenovirus, HPV, and
mycoplasma
. Used various DNA and RNA purification techniques
. Supervised multiple technical staff
. Expertise with TaqMan technology using Applied Biosystems ABI
Prism 7700 Sequence Detection System
. Wrote development reports and presented at Scientific
Advisory Board meetings
. Gave presentations and had discussions with clients
(representatives from pharmaceutical companies)
1998-1999 Veritas, Inc. 679 Southlawn Lane, Rockville, MD 20850
Research Scientist, Molecular Biology Client Services
. Performed various molecular biology techniques such as,
plasmid preparation, transformation, PCR optimization,
cloning, and site-directed mutagenesis
. Developed SOP for recombinant protein expression including,
construction and verification of various bacterial expression
vectors
. Directed technical staff on purification process and
enzymatic cleavage of recombinant protein
. Performed automated fluorescent DNA sequencing using Applied
Biosystems ABI Prism 310 Genetic Analyzer
. Interact with customers and potential customers, worked at
the company's exhibition booth at local trade shows (i.e.
NIH)
1996-1998 NINDS, NIH Bethesda, MD 20892
IRTA Postdoctoral Fellow, Neurotoxicology Section
. Independently planned and conducted research on three
different projects studying the human polyomavirus JC virus
(JCV); investigated the effects of natural variants of the
large T-antigen from different genotypes of JCV on viral
replication and infectivity, mechanism of genetic
recombination of rearrangements in the regulatory region,
genotyping Asian strains of JCV
. Ad hoc reviewer for several journals
. Managed my own budget for 1997-1998 fiscal year
. Supervised HHMI summer student
1990-1996 Johns Hopkins University Baltimore, MD 21218
Predoctoral Graduate Student, Department of Biology
. Utilized molecular, biochemical, and immunological techniques
such as, gene expression, library construction, PCR,
automated DNA sequencing, Western blotting, and protein
purification to study the nitrogen-fixing bacterium
Azotobacter vinelandii
. Presented at national and international meetings
. Supervised graduate and undergraduate students
. Ad hoc reviewer for several journals
1989-1990 NIDDK, NIH Bethesda, MD 20892
Chemist, Genetics and Biochemistry Branch
. Ordered and organized supplies, maintained equipment in
proper working order and arranged for service, maintained
solutions, buffers and reagents so they are available and
suitable for experiments
. Responsible for growing and storing on a large scale HeLa
tissue culture cells
. Research project using molecular methods, such as
oligonucleotide synthesis, radiolabelling of oligos, and strand
exchange assays (RecA assays), etc. to study triplex DNA
intermediates in RecA recombination which is involved with DNA
repair
. Participated and presented in laboratory meetings and journal
clubs
. Responsible for storage, use and disposal of hazardous materials
1988-1989 University of Maryland College Park, MD 20742
Undergraduate Researcher, Department of Biochemistry
. Under Dr. Brusilow's supervision, conducted experiments utilizing
molecular, genetic, and biochemical techniques, such as
cloning, DNA preparation, Southern hybridizations, DNA
sequencing, and fluorescence quenching assays, etc. to study
the bioenergetics of the proton-translocating ATPase of E. coli
to examine the role of the ? subunit in the assembly of ATPase
and thus energy production in the cell
. Designed and performed experiments, as well as planned
future experiments, accurately and clearly recorded findings
and interpreted results
. Participated and presented in laboratory meetings
. Co-author on a poster presentation describing the
laboratory's work at a national scientific meeting
. Co-author on a manuscript containing data from my project
Education
1997, Ph.D. Molecular Biology Johns Hopkins University, Dept. of
Biology, 1990-1996
1989, B.S. Biochemistry University of Maryland, College Park,
1985-1989
Professional Associations
President, University of Maryland College of Chemical and Life Sciences
Alumni Chapter
Member, Licensing Executives Society USA and Canada (LES)
Member, American Association for the Advancement of Science
Member, American Society for Biochemistry and Molecular Biology
Member, American Society for Microbiology
Publications
Angov, E., T. C. N. Ng, and W. S. A. Brusilow. 1991. Effect of the ?
subunit on assembly and proton permeability of the F0 proton channel of
Escherichia coli F1F0 ATPase. J. Bacteriol. 173: 407-411.
Ng, T. C. N., A. N. Laheri, and R. J. Maier. 1995. Cloning, sequencing, and
mutagenesis of the cytochrome c4 gene from Azotobacter vinelandii:
characterization of the mutant strain and a proposed new branch in the
respiratory chain. Biochim. Biophys. Acta 1230: 119-129.
Ng, T. C. N., J. F. Kwik, and R. J. Maier. 1997. Cloning and expression of
the gene for a protein disulfide oxidoreductase from Azotobacter
vinelandii: complementation of an Escherichia coli dsbA mutant strain. Gene
188: 109-113.
Jobes, D. V., J. S. Friedlaender, C. S. Mgone, H. T. Agostini, G. Koki, R.
Yanagihara, T. C. N. Ng, S. C. Chima, C.F. Ryschkewitsch, and G. L. Stoner.
2001. New JC virus (JCV) genotypes from Papua New Guinea and Micronesia
(Type 8 and 2E) and evolutionary analysis of 32 complete JCV genomes. Arch.
Virol. 146: 1-17.