Medical Engineer
Resume:
Ashish Hinger
**** ****** **. ***#***, Ann Arbor, MI 48105
Email id: ******.******@*****.***
Phone # 585-***-****
Education
. Master of Science - Biomedical Engineering (Signal and Image Processing)
o University of Texas at Arlington and University of Texas
Southwestern Medical center, Dallas, Texas, United States
. Bachelor of Engineering - Biomedical Engineering
o University of Rajasthan, Jaipur, India
Experience:
University of Michigan, Ann Arbor, Michigan, USA
2010 - Present
Research Engineer
Responsibilities:
. Developing and Designing low cost portable handheld Ultrasound medical
diagnostic imaging device. HW (frontend and backend) design &
development (Xilinx, Altera, AD, TI; Eagle, SPICE, VHDL). Signal &
Image processing algorithm development (MATLAB, C++) for Ultrasound
Diagnosis.
. Developing and Designing low cost portable CW, PW Ultrasound Doppler
device (HW+SW) for Vascular applications, Signal & Image processing
algorithm development (MATLAB, JAVA, C++)
. Developing elasticity Imaging (Mechanical Imaging, Motion tracking)
and Doppler related algorithms for Signal & Image processing (MATLAB,
C
. Writing Research papers and Grants applications for funding (R21, R01,
SBIR, etc).
. Transducer-Image simulation (PZT, CMUT using Field II, COMSOL). System
designing, Software (GUI), hardware development and debug handling
(FDA regulated) and documentations.
. Software development - object-oriented design and implementation, high
performance and quality oriented, passion in designing, writing and
maintaining clean, professional, and maintainable code.
Siemens Medical Solution, Mountain View, California, USA
August 2008- August 2009
Research Engineer
Responsibilities:
. Specify, model, simulate, test (automate) and optimize beamformation
and imageformation techniques with signal and image processing
algorithms (MATLAB, C, C++; CPU/GPU)
. Analyze, design, develop, implement imaging algorithms and control
software to drive beamformation, signal and image processing
capabilities in ARFI, B-Mode, Color Doppler and Spectral Doppler mode
. Conducts research, identify, design state-of-the-art algorithms & open-
source implementations (IPP, OpenCV, OpenGL, OpenCL, CUDA, ITK, VTK,
Direct3D, XIP/RAD, etc.) in the field of Computer vision, medical
imaging, applied machine learning, 3D/4D segmentation, tracking,
fusion (MRI & CT), and pattern recognition to generate libraries
(Software development). PACS Application development - 'Fusion
imaging' to integrate modalities like US/CT/MRI & Ultrasound for
rendering, segmentation (6/26 nearest neighbor region growing - volume
algorithm for PACS), concurrent analysis (probabilistic boosting tree
based classifier/detector, automated volumetric cardiac ultrasound
analysis)
. Volumetric Myocardial Mechanics (VMM) - SVM, Delaunay triangulation -
Mesh, Area, Isosurface, K-point, element, based algorithm development
for analysis of heart, to map shear stress, strain & tissue velocity
on real time 3D volume echocardiogram (DICOM, HL7, HIS, RIS, PACS,
EMR)
. Transducer analysis & development, acoustic modeling, acoustic test
measurements (HIFU, water tank, hydrophones using Field II, LAVIEW,
python, MATLAB)
. HW/SW architecture (including embedded) understanding of systems and
transducers (including ACUNAV 3D Catheter) with real-time 2D/3D mode,
M/Color/Doppler/Flow/spectral mode, RX/TX beam/Image forming,
coherent/incoherent, retrospective, algorithms, etc.
. Analyze existing software, validate, develop and document the
algorithm, program flow and functionalities. Image Quality management
and Clinical workflow design, implementation, validation for agile
software development on Ultrasound volumetric imaging system (SC200
echocardiography), S2000 (General/OB/GYN and Automated Breast Volume
Imaging), P10, P50, X300, U-system (ABS), Sequoia, etc.
Course Work
Graduate
Digital Signal Processing, Statistical Signal Processing, Optics, Digital
Image Processing, Computer Vision, Machine Learning & Pattern Recognition,
Neural Networks, MEMS, Instrumentation, Medical Imaging - Brain Functional
Imaging (fMRI), Human Physiology (Anatomy), Advance Neuroscience
Undergraduate
Computational Biology, Biological Database & Management, Biostatistics,
Bioinformatics, Genetic Engineering, Biochemistry, Microbiology, Cell
biology, Immunology, Chemical Process Calculation, Unit Operation of
Chemical Engineering, Molecular Genetics, Biochemistry, Developmental
Biology, Dairy technology, Analytical Technique, Thermodynamics of
Biological System, Recombinant DNA Technology, Industrial Microbiology and
Enzyme Technology, Chemical Engineering Thermodynamics, Heat Transfer,
Object oriented programming in C++, Genome Analysis, Biostatics,
Fermentation Technology and Downstream Processing, Food Biotechnology, Mass
Transfer, Bio monitoring, Instrumentation and Process Control,
Environmental Biotechnology, Database Management Systems, Bioinformatics,
Molecular Diagnostic Techniques, Transport Phenomena, Marketing Management.
Technical Skills:
HPLC, GC/MS, GC/HS, DNA Sequencing, Fluorescence Microscopy, extraction of
active compounds, Thin Layer Chromatography, Column Chromatography,
Spectrophotometer, Gel-Electrophoresis, fMRI
C, C++, Visual Basic, ANSYS, Fluent, OpenGL, XIP/RAD, parallel computing,
SQL, ORACLE, Solaris, AIX, LINUX, JAVA, MySQL, WordStar, Lotus, FoxPro,
HTML, PERL/BioPERL, Bioinformatics Tools, LabView, .NET, Matlab,
computational fluid dynamics software, HP-UX, VLSI, BioPac (EMG, EEG, EOG,
GSR-Polygraph, ECG), ANSYS, Analyze, SPM, Brain Voyager, VMD, NAMD, Field
II - ultrasound transducer simulator, ProE, CAD, Solidworks, SAP,
ClearCase, ClearQuest,
Activities
. Two international level technical paper / poster presentations &
publication on
o Bio Nanotechnology & virus detection
o Integration of biology and engineering at the micro and
nanoscale: Integrated biochips to self-assembly of electronics.
. Four national level technical paper / poster presentations &
Publication on
o Nanotechnology; *Nanotechnology & Carbon Nanotubes; *Biosensors
& BioMEMS;
o Hybrid Engineering: Future models for Ultimate Sensing,
Detection & Analysis
. Scientific Workshop on "Nanotechnology" at IIT Delhi.
. Biohorizon on Biochemistry Engineering and Biotechnology
. Bioprocess Engineering
. Designed a webpage based on Biotechnology Tutorial during college
competition.
Projects:
The University of Texas at Arlington
August 2007 - August 2008
1. GTA for Transport Phenomenon (Fluid dynamics, heat, mass & momentum
transfer)
. Delivered lectures on Fluid mechanics (Transport phenomenon) and
algorithms development using perl and C++ for Fluid-Structure
Interaction, mesh generation, flow visualization, etc. on various
transport phenomenon's.
2. 3D Ultrasound assisted remote robotic neurosurgery (spine) using co-
registered multimodality imaging.
3. Medical (DICOM) Signal and Image processing (MATLAB, C++, Intel IPP,
OpenCV)
. Pattern Recognition and machine learning for segmentation using a robust
combination of Conditional Random Function and Level set segmentation
using JAVA.
. Detecting shape classes of variable structure in cluttered images using
Hidden State Shape models. Design of Feed-forward neural networks via
regression, Multilayer perceptron (MLP) neural network, functional link
nets and higher order neural nets, Training algorithms, Backpropagation,
Estimation capabilities of feed-forward neural networks, Performance
bounds, Conventional mappings such as Volterra filters, Conventional and
neural net classifiers, Bayes and nearest neighbor classifier, RBF,
Support vector machines, Statistical learning, Clustering algorithms
such as k-means, sequential leader, self-organizing map, Clustering-
related neural nets such as Kohonen's LVQ (learning vector
quantization), modular nets, radial basis function nets and counter-
propagation nets, Neural networks for associative memory including
linear associative memories.
. Projects on (DICOM) Medical Image processing using MATLAB and C/C++
includes Quantization, Lloyd-Max Quantizer for Rayleigh PDF, Moire
Effect, Zooming with Interpolation, Color Transformation, 2D-DCT
Geometrical Zonal Filters, Performance Comparison of KLT/DCT/DFT, DCT-II
B, DFT, Root & Zonal Filters, Inverse Gaussian Filter (IGF), Image
Enhancement, Inverse & Wiener Filtering, Constrained Least Squares
Restoration, Geometric Mean Filter, 2-D DPCM, Lossless Predictive
Coding, Progressive to Interlaced and Interlaced to Progressive
conversion, SSIM Structural similarity index using JAVA.
. Projects on statistical signal processing using Least squares analyses,
Shaping filters, Wiener filters, AR modelling, Toeplitz recursion,
conjugate gradient technique, singular value decomposition, Adaptive
Noise Cancellation, Maximum likelihood and MAP estimation, Cramer-Rao
lower bound, Data compression for parameter estimation.
. Projects on Medical CAD includes Color manipulation and filtering, Canny
edge detection, edge-based detection, Probabilistic Image Modeling,
Skin/hand/face detection, Hough transforms, contour detection via
dynamic programming, pattern recognition based on recognition moments,
Euclidean distance, edge; motion tracking & recognition, 3D
reconstruction, segmentations using JAVA.
4. Multi exponential Curve fitting algorithm on optical signal for
Diagnosis of cancer
. Algorithm to fit optical data from fluorescence (auto) in C++ and MATLAB
is developed. It is used to standardize data for cancerous diagnosis in
terms of lifetime, amplitude Imaging.
5. Flow sensor in Micro channel pulmonary Membrane Blood Oxygenator
. The use of Micro channel pulmonary Membrane Blood Oxygenator overcomes
the plasma leakage (wet out) and low mass transfer problems of
conventional methods. At nano scale various parameter like flow rate,
pressure, shear stress play an important role. Sensors, compatible with
blood is use to detect various governing parameters during the flow and
integrated on Micro channel membrane by surface micro machining.
. The basic design includes a MEMS thermal sensor used to determine the
flow rate of the blood through the channel.
6. High throughput Nanochannel Array for $1000 genome sequencing Using
Single Genomic DNA Molecules
. It is considered that a single DNA molecule can be better stretched and
controlled along a nanofluidic channel, and that it could be detected
with higher sensitivity and spatial resolution. The cutting edge
nanofluidic technologies do not allow for a high sample throughput due
to the lack of the manufacture-oriented protocol for nanochannel
preparation and rapid stretching of single DNA molecules. Molecular
Dynamics (VMD) simulation is used to study the trapping and stretching
of a single stranded (ss) DNA in a nanochannel, the interaction between
ssDNA and silicon oxide channel surface, the trapping mechanism,
stretching process, and sequencing process, impact of nanochannel width
and DNA stretching length for design optimization, and Modeling and
Simulation of DNA trapping, stretching, and sequencing in Nanochannel.
7. Diagnosis of Abnormal Tissue using Auto-Fluorescence
. The obtained fluorescence-lifetime and intensities of both reflected and
fluorescent signal from PicoStar camera system characterizes the
specific tissue condition. Lifetime and Intensity analysis helps us to
diagnoses the abnormal tissue. Ratio of the fluorescence signal to
diffusive reflection signal is proportional to intensity of tissue auto
fluorescence. Normal tissue efficiently emits fluorescence than
neoplastic lesions. The raw fluorescence image is recorded with time
gated PicoStar ICCD camera (LaVision). It can be Diagnosised by
analyzing the measurements of the parameters from Fluorescence and
Reflectance light.
8. Mechanical interaction between the cell and the substrate by Uni-axial
Stretching and interfaced using LABVIEW for motion control
. The motorized stage with a PC-controlled (4 Axis Servo Amplifier) and NI
PCI-7344
. Control Board compatible with LABVIEW (Controls the motion) is used to
study cell under mechanical stress.
9. Functional brain imaging data analysis using HomER (Hemodynamic Evoked
Response) and MATLAB
10. Image Analysis using AFNI (Analysis of Functional NeuroImages) for
visual stimuli (BOLD, fMRI).
11. Biological signal processing of MIT-BIH Arrhythmia Database (ECG) using
MATLAB.
. The ECG signal is used to determine number of heart beat, duration of
time interval, autocorrelation, power density spectrum, and filtering to
remove component exceeding desired frequency and filtered signal is also
analysis.
12. Time-gated optical system for depth-resolved functional Brain imaging
. The Use of a number of fibers of different lengths creates an optical
delay, and enabling simultaneous detection in a number of windows by
steps of picoseconds for each detector to get depth-resolved Image.
Monte Carlo Simulation used.
13. Research on Micro channel Membrane blood Oxygenator
. The permeability of oxygen on polymer coated multi membrane, fabricated
by Silicon wafer surface micro machining depends on channel dimensions.
A multi channel membrane is fabricated.
Asenterra Systems Pvt. Ltd., Bangalore, India
January 2007 - June 2007
. Proteomics, Genomics, Homology Modeling, Mutation Studies of disease
causing genes present on X chromosome like HEMA, ATP7a, MECP2, and HPRT1
with Drug Designing using C++ (Blast) and Bio perl approach under Dr.
Vidya Niranjan, Senior Research Scientist (chief)
Laboratory of Bio-Molecular Technology, M. L. Sukhadia University, India
July 2006 - August 2006
. Clinical Trial, Production of Secondary Metabolites in Culture,
techniques of plant cell and tissue culture, Fluorescence Microscopy,
extraction of active compounds, Thin Layer Chromatography, Column
Chromatography, Spectrophotometry, Gel-Electrophoresis, and Microbiology
based analysis using perl and C++ under Prof. K. Ramawat, Coordinator
(UGC-DRS, DST-FIST).
Directorate of Forensic Science, Forensic Science Laboratory (India)
April 2005 - May 2005
. DNA Profiling/Fingerprinting and Forensic Genetics (PCR/ASO DNA
amplification for 11 loci in Human by Automated sequencer ABI-PRISM:
Applied BioSystems) using C++ & Biotechnology application in Forensic
Science (perl) under Dr. A.K. Mehta (Assistant Director DNA Division)
AuxiCogent (Quatrro), India
June 2007-July 2007
. Technical Support for satellite Internet Providers - HughesNet
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