Charles D. Mills, Ph.D. Short Resume
Marine on St. Croix, MN 55047
Cell Phone: 612-***-****
Email: ********@***.***
Goal
I would like to find a position near Stillwater that takes advantage of my
broad work and professional experience.
Background and Experience
Until 2006, I was a Medical Research Professor in the Surgery Department at
the University of Minnesota. My expertise is the immune system. I funded
my laboratory, employees, and research through medical grants and
publications. During my career, I developed a new concept for how the
immune system reacts to different conditions, such as cancer, diabetes and
wounds, by discovering 2 new "white" cells: one which fights infections,
and the other that heals wounds (publication list below). I named them M-1
and M-2, and this nomenclature is now used worldwide in medical research.
Having achieved this medical milestone, I became eager to use my creativity
and superior writing and speaking abilities in the private sector.
Currently, I am Head of Biology and Sales at Biolawn, a lawn and property
care located in Afton, MN. Using my scientific background, and
communication/sales abilities, I have spearheaded a doubling of the size
of the company in 2 years. Biolawn's business is seasonal.
So, I would like to find either a year round position, or a job (or
contract) to supplement my Biolawn Position.
My strongest skills and interests include: communication/direct sales,
organization, and writing. I am also 6'5"/very fit, and enjoy manual
labor.
Other activities I am currently involved with include: developing a product
that utilizes solar energy, and coaching basketball.
I have 2 children: a daughter (Audrey) who is a junior at Macalester
College in St. Paul, Minnesota, and a son (Charles Jr.), in tenth grade in
the local Forest Lake School District. Below is a recent photo of me and
my son and daughter (2nd, 3rd, and 4th from left).
[pic]
Education
School Degree Major Year
Deerfield Academy/Deerfield MA H.S. - 1970
Syracuse University/Syracuse NY B.S. Biology
1974
University of Chicago/Chicago IL Ph.D. Immunology
1980
Professional Experience:
Trudeau Institute/Saranac Lake, NY Postdoc Fellow with Robert North,
Director 1980-85
Brown University/Providence, RI Assistant Professor/Medical
School/Surgery 1985-90
Univ. of Minnesota/Minneapolis, MN Assoc. Professor/Medical School/Surgery
1991-06
BioLawn, Inc./Afton, MN Head of Biology and Sales
2009 to present
Other Experience/Employment:
Boat Sales and Service/Engine Mechanic: Edinburg Marina, Edinburg, NY
1966-1968
Laborer/Driver/Road Construction: Speculator, NY
1969
Salesman: Fuller Brush Company, Denver, CO 1970
Kitchen Help: Nathan Littauer Hospital, Gloversville, NY
1971
Lifeguard/Campsite Worker: NY State Environmental Department
1971
Fork Lift Operator: Hussmann Manafacturing, Gloversville, NY
1972
Boat Sales and Service/Engine Mechanic: Sacandaga Marina, Mayfield, NY
1974
Hematology Technician: Crouse-Irving Memorial Hospital. Syracuse, NY
1972-74.
Clinical Immunology Technician: University of Chicago
1976-79.
Lifeguard: University of Chicago 1978
Head Radiation Safety Officer: Trudeau Institute
1980-85.
Animal Care Committee: Brown University 1987-
88
Medical School Admissions Committee: University of Minnesota
2001-05
Teaching and Lecture Experience:
I have taught immunology to graduate and medical students, and organized
and supervised journal clubs and seminars at Brown University and the
University of Minnesota. I have mentored many undergraduate, graduate and
medical students in my laboratories. I have been an invited speaker at
meetings in the US and abroad in the areas of cancer, diabetes and wound
healing.
Selected Publications (of a list of 54)
Hering, B.J., M. Wijkstrom, M.L. Graham, M. Hardstedt, T.C. Aasheim, T.
Jie, J.D. Ansite, M. Nakano, J. Cheng, W. Li, K. Moran, U. Christians,
C. Finnegan, C.D. Mills, D.E. Sutherland, P. Bansal-Pakala, M.P.
Murtaugh, N. Kirchof, H.J. Schuurman. 2006. Prolonged diabetes reversal
after intraportal xenotransplantation of wild-type porcine islets in
immunosuppressed nonhuman primates. Nature (Med) 12:301.
Mills, C.D. 2001. Macrophage arginine metabolism to ornithine/urea or
nitric oxide/citrulline: A life or death issue. Critical Reviews in
Immunol. Vol. 21, Issue 5, Pgs. 399-425.
Mills, C.D., K. Kincaid, J. A. Alt, M. J. Heilman, A. H. Hill. 2000. M-
1/M-2 Macrophages and the Th1/Th2 Paradigm. J. Immunol. 164:6166.
Medot-Pirenne, M.J. Heilman, M. Saxena, P.E. McDermott, C.D. Mills. 1999.
Augmentation of an antitumor cytotoxic T lymphocyte response in vivo by
inhibition of "suppressor" macrophage nitric oxide. J. Immunol.
163:5877.
Stevens, R.B., D.E.R. Sutherland, J.D. Ansite, M. Saxena, T.J. Rossini,
B.K. Levay-Young, B.J. Hering, C.D. Mills.1997. Insulin down regulates
the iNOS pathway: Nitric Oxide as cause and effect of diabetes? J.
Immunol. 159:5329.
Mills, C.D., J.D. Shearer, R. Evans, M.D. Caldwell. 1992. Macrophage
arginine metabolism and the inhibition or stimulation of cancer. J.
Immunol. 149:2709.
Mills, C.D., J.D. Shearer, M.D. Caldwell. 1992. Macrophage arginine
metabolism via synthase or arginase equates with immunosurveillance or
immunostimulation of cancer. In: Biology of Nitric Oxide. S. Moncada,
M.A. Marletta, and J.B. Hibbs, Eds., London; Chapel Hill: Portland
Press.
Mills, C.D. 1991. Molecular basis for "suppressor" macrophages: arginine
metabolism via the nitric oxide synthetase pathway. J. Immunol.
146:2719.
Pricolo, V.E., M.D. Caldwell, B. Mastrofrancesco, C.D. Mills. 1990.
Modulatory activities of wound fluid on fibroblast proliferation and
collagen synthesis. J.Surg. Res. 48:534-538.
Albina, J.E., M.D. Caldwell, W.L. Henry, C.D. Mills. 1989. Regulation of
macrophage functions by L-arginine. J. Exp. Med. 169:1021.
Mills, C.D., M.D. Caldwell, D.S. Gann. 1989. Evidence of a transient
"window" of immunodeficiency following trauma of rats. J. Clin.
Immunol. 9:139.
Mills, C.D., R.J. North. 1983. Expression of passively transferred
immunity against an established tumor depends on generation of
cytolytic T cells in recipient. Inhibition by suppressor T cells. J.
Exp. Med. 157:1448.
Albina, J.E., M.D. Caldwell, W.L. Henry, C.D. Mills. 1989. Regulation of
macrophage physiology by L-arginine. Role of the oxidative L-arginine
deiminase pathway. J. Immunol. 143:3641.
Mills, C.D., R.J. North. 1985. Ly-1+2-suppressor T cells inhibit the
expression of passively transferred anti-tumor immunity by suppressing
the generation of cytolytic T cells. Transplantation 39:202.
Mills, C.D., R.J. North, E.S. Dye. 1981. Mechanisms of anti-tumor action
of Corynebacterium parvum. II. Potentiated cytolytic T cell response
and its tumor-induced suppression. J. Exp. Med. 154:621.
Dye, E.S., R.J. North, C.D. Mills. 1981. Mechanisms of anti-tumor action
of Corynebacterium parvum. I. Potentiated tumor-specific immunity and
its therapeutic limitations. J. Exp. Med. 154: 609.
Research Grants
I supported myself as a Medical Research Professor through grants averaging
about $150,000/year. A few examples are listed below.
1. "M-1/M-2 Macrophages"
Principal Investigator: Charles D. Mills
Agency: NIH
Project Duration: 8/1/02 -7/31/04
The main purpose of this investigation is to more clearly delineate the
properties of M-1/M-2 macrophages and how they influence immune
responses.
2. "M-1/M-2 Macrophages and the Fate of (-Cells"
PRINCIPAL INVESTIGATOR: CHARLES D. MILLS
Agency: Juvenile Diabetes Foundation
Project Duration: 1/01/01 - 12/31/03
The main purpose of this investigation was to study macrophage function
in islet cell transplantation to increase islet/(-cell survival (cure
diabetes).
Extracurricular Activities/Hobbies
. Coaching boys and girls basketball
. Vegetable Gardening
. Basketball/Golf/Water and Snow Skiing
References Gladly Available