State University Health Care

Kate Kovacheva

*** *. ****** **, ***. *, Carson, CA 90745 • 310-***-**** • ***********@*****.***

Objective

Seeking a lab position in research that can benefit and improve the health care field.

Education

M. S., Molecular Biology, California State University, Northridge 2011

Isolated and analyzed the anthocyanidin synthase gene from several Hawaiian

silverswords and their mainland relatives - California tarweeds, and investigated its

evolution in this diversifying lineage

B. S., Biology, California State University, Dominguez Hills 2006

Skills

Molecular techniques: DNA/RNA isolation, PCR, iPCR, RACE, electrophoresis,

cloning, transformation, minipreps, restriction enzyme digestion, competent cells

preparation, immunohistochemistry, immunocytochemistry, enzyme immunoassays

(EIA), fluorescent and bright field microscopy.

Computer skills: PC/Windows/Microsoft Office, Mac OS X, Endnote. Bioinformatics

tools: Pubmed, NCBI, BLAST, BioEdit, Biology Workbench, MEGA 4 and 5, PAUP 4.0,

MrBayes, PHYML, PHYLIP, PERL.

Languages: English, Bulgarian, Russian.

Experience

Research Associate 2008 to present

Biology Department, California State University, Northridge, CA

Isolated and analyzed the ANS gene using molecular biology techniques and

bioinformatics tools

Performed lab maintenance: prepared materials for lab use, ordered and organized

supplies and waste, maintained records, observed safety regulations, trained and

counseled students

Skilled in literature research, preparing oral and written presentations and grant

proposals

Currently, organizing and maintaining the lab under operating costs

Teaching Associate 2008-2011

Biology Department, California State University, Northridge, CA

Lectured and instructed introductory Biology lab courses

Research Associate 2007-2009

Charles R. Drew University of Medicine and Science, Los Angeles, CA

Elucidated the signaling pathway of testosterone-induced hypertrophy in aging

muscle using protein detection techniques, such as immunohistochemistry and

enzyme immunoassays

Collected mouse tissues and prepared them for storage and use

Collected and analyzed data from the resulting stained tissues using bright field and

fluorescent microscopy, MS Excel and SigmaStat

Presented findings at scientific meetings, reviewed manuscripts for publishing and

trained students in lab techniques

Publications

Ekaterina Kovacheva. Master’s thesis. Evolution of the anthocyanidin synthase

2011

gene in Hawaiian silverswords and California tarweeds. CSU Northridge, CA

91330.

2010 Ekaterina Kovacheva, Amiya Sinha-Hikim, Ruoqing Shen, Indrani Sinha, Indrani

Sinha-Hikim. Testosterone Supplementation Reverses Sarcopenia in Aging

through Regulation of Myostatin, c-Jun NH2-Terminal Kinase, Notch, and Akt

Signaling Pathways. Endocrinology, 151(2): 628-638.

2010 Indrani Sinha-Hikim, Ruoqing Shen, Ekaterina Kovacheva, Albert Crum,

Nasratola Vaziri, Keith Norris. Inhibition of apoptotic signalling in spermine-

treated vascular smooth muscle cells by a novel glutathione precursor. Cell

Biology International, 34(5): 503-511.

2009 Danielle Brown, Amiya P Hikim, Ekaterina L Kovacheva, Indrani Sinha-Hikim.

Mouse model of testosterone-induced muscle fiber hypertrophy: involvement of

p38 mitogen-activated protein kinase-mediated Notch signaling. Journal of

Endocrinology, 201(1): 129-139.

2008 Melissa Braga, Amiya P Sinha-Hikim, Sanjit Datta, Monica G Ferrini, Danielle

Brown, Ekaterina L Kovacheva, Nestor F Gonzalez-Cadavid, Indrani Sinha-

Hikim. Involvement of oxidative stress and caspase 2-mediated intrinsic pathway

signaling in age-related increase in muscle cell apoptosis in mice. Apoptosis,

13(6): 822-832.

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