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Customer Service Quality Assurance

Location:
8107
Posted:
July 26, 2011

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Resume:

Katherine Finnerty Kaiser

*** ******* ******

Collingswood NJ 08107

Phone: 856-***-****

E-mail: ********@*******.***

Professional Experience

SunGard Asset Management Systems - Malvern PA

Senior Technical Support Specialist (March 2003 - Present)

. Experience working in a Global environment interacting with clients in

the Customer service area, as well as training personnel for technology

transfer.

. Software: Microsoft Office, UNIX OS, Windows OS, VAX/VMS OS, Global Plus,

ORACLE, Autosys, SMIT, Legato, ftp, ndm, telnet, WebSphere 6.1, XSP,

Unix visual editor, SQL, familiarity with Perl

. Oracle 9i, 10g, and 11g software and critical patch set installations on

test and production boxes. Refresh, restore, and recover oracle

databases from cold and hot backups as well as creation of new oracle

databases. Familiar with RMAN.

. Yearly rebuilds of Client databases to most current GlobalPlus Release

. Quarterly Maintenance Upgrade Patches (MUPS) applied to production and

test environments. Weekly patch installations to production and test

systems. Global Office and Power Image patch installation and updates.

. Execute closing of financial day for clients, and manage related data

communications from vendors to the processing center and to clients

. Weekly system backups of 40 Production and Test Aix boxes using Legato

backup software

. Troubleshoot and resolve application, scripting and system related issues

. Provide technical support to clients, development, and quality assurance

teams and familiar with changeman

SmithKline Beecham Pharmaceuticals, (GlaxoSmithKline), Upper Merion, PA

Gene Expression Sciences Department-Scientist (1994-October 1997)

. Integral role in the development of a manufacturing cell line for the

first fully human antibody developed at SmithKline Beecham; responsible

for expression, subcloning, and development of a stable human cell line.

This was important in establishing that our human antibody subgroup was

capable of moving a fully human antibody through the cell line

development process.

. Generated stable cell lines expressing a number of seven Transmembrane

Receptors.

. Expression and analysis of several antibody candidates from hybridoma

rescue and combinatorial efforts. Met tight timelines by rapidly

evaluating candidates at very early stages using high-throughput

screening methods utilizing Western and Elisa specificity and

Immunoglobulin concentration; thus enabling selection of lead candidates

earlier.

. Proficient in basic transfection and electroporation procedures for Gene

Expression. Expressed a variety of clones, antibodies, and receptors in

Mammalian and Drosophila Expression systems.

. Cloned and analyzed genes for integrity using GCG and Lasergene software.

. Initiated a change of many stock tissue culture media for three

departments to include supplements, thereby decreasing the risk of

mistakes while saving time and money.

. Present data on a routine basis at Departmental Data Club and Team

meetings. Work effectively, train and offer assistance to a number of

groups.

Molecular Genetics Department - Scientist (1991-1994)

. Combinatorial approach to generating RSV antibodies. Analyze clones

specific for heavy and light chains by traditional and PCR methods.

Biopanning of antibodies to enrich for phage bearing fragmented

monovalent antibodies (FABS) with the higher affinity for the respective

Antigen. Convert Fabs to Mabs by cloning Fab into appropriate vectors.

Analysis of converted Mabs and characterization of antibodies.

. Used traditional hybridoma technology to generate and characterize panels

of neutralizing murine monoclonal antibodies to (1) human IL-5 and (2)

recombinant human PLA2

. Produce serum free cell lines essential to continual work for a number of

team projects (PLA2, IL-5, RSV)

. Proficient in basic techniques in molecular biology, Biacore, and

robotics.

Cell Sciences Department - Associate Scientist (1988-1991)

. Generation of monoclonal antibodies for TPA, TNF, PLA2 and IL5 -

Performed immunizations of animals, test bleeds, fusions, cloning and

final characterizations of antibodies. Characterizations of antibodies

included: isotyping, partial purification, immunoglobulin quantitation,

and specificity (ELISA). Developed specialized assays such as

Immunoglobulin quantitation assay, competition assays, and assays that

mimic Immuno Affinity Columns

. Sterility testing with animal cell cultures.

. Familiarity with Geysen Assay techniques and Flow Cytometry.

Coriell Institute for Medical Research Camden NJ

Research Technician, April 1986-March 1988

. Tissue Culture methods utilizing asceptic techniques.

. Protein quatitation and Enzyme Activity Assays to determine

hypophosphatasia and Cystic Fibrosis in cell and serum samples.

. Monoclonal Antibody characterization used in Prenatal Diagnosis of Cystic

Fibrosis.

. Iso- Enzyme Electrophoresis studies for all cell lines in (NIGMS) Human

Genetic Mutant Cell repository and (NIA) Aging Cell repository Catalogs.

. General Molecular Biology techniques such as DNA isolations, plasmid

preparations, Southern Blot analysis, hybridizations and transformations

procedures were employed for prenatal diagnosis of Cystic Fibrosis

. Organize work schedule, order laboratory supplies, maintain records,

perform equipment maintenance, train personnel, review current literature

Scientific Publications

White JR, Imburgia C, Dull E, Appelbaum E, O'Shannessy DJ, Brawner M,

Fornwald J, Adamou J, Elshourbagy NA, Kaiser K, Foley JJ, Schmidt DB,

Johanson K, Macphee C, Moores K, McNulty D, Scott GF, Schleimer RP, Sarau

HM, Cloning and functional characterization of a novel human CC chemokine

that binds to the CCR3 receptor and activates human eosinophils. J Leukoc

Biol. 1997 Nov; 62(5):667-75

Ames RS, Tornetta MA, McMillian LJ, Kaiser KF, Holmes SD, Appelbaum E,

Cusimano DM, Theisen TW, Gross, MS, Jones CS et al. Neutralizing murine

monoclonal antibodies to human IL-5 isolated from hybridoma and a

filamentous phage Fab display library. J Immunol. 1995 Jun 15; 154(12);

6355-64

Henri E, McMillian L, Trulli S, Kaiser K, Lee E, Franklin S, Jonak Z.

Poster presented to 13th Annual Philadelphia Immunology Conference,

Philadelphia PA, October 1992. Generation and Role of Monoclonal

Antibodies in Development of Recombinant Tissue Plasminogen Activator

Molecules

Education

Villanova University, 21 Graduate credits in Molecular Biology (1988- 1991)

University of Delaware, Bachelors of Science in Biology (1985)

Coriell Institute for Medical Research, Camden NJ

Post Doctorate Course in Genes Genomes and Genetics (October 1989)

Post Doctorate Course in Topics in Toxicology (October 1987-April

1988)

Post Doctorate Course in Molecular Biology (October 1986-May 1987)

Oracle University

Oracle Database 11G Administrator Workshop II (March 2008)

Oracle Database 10G Administrator Workshop I (August 2006)

Introduction to Oracle 9i- SQL (April 2005)

Awards

Sungard Asset Management Systems Star Employee of the Year, January 2007

SmithKline Beecham, Bronze Award for work on identifying and testing the

first fully human RSV antibody developed at SmithKline, June 1996

SmithKline Beecham, Impact Award for work on recombinant IL5 antibodies,

June 1994

Reference available upon request



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