Supervisor Assistant

JOAN GO SCHELLINGER, Ph.D.

*************@*****.***

SUMMARY

A goal-oriented and highly motivated individual demonstrating the ability to think critically, learn new concepts and

techniques, multi-task and meet deadlines; functions in a dynamic and diverse environment with a strong

capability to lead, manage, and mentor others. Expertise and skills include:

Materials development: synthetic organic chemistry, solid-phase peptide synthesis, bioconjugate chemistry and

polymer synthesis

Characterization, purification and analytical techniques: 1D and 2D NMR Spectroscopy, ESI-MS(LTQ Orbitrap),

MALDI-TOF, CD Spectroscopy, SDS-PAGE, fluorescence microscopy, IR Spectroscopy, Flow Cytometry,

Transmission electron microscopy, DLS, GPC/SEC, HPLC and flash column chromatography.

Biochemical techniques: cell culture and in-vitro gene transfection assays.

Excellent organizational and communication skills.

EDUCATION

University of California, Davis – Ph.D., Chemistry 2005-2010

Dissertation: Design and Synthesis of Multivalent Constructs via Cu(I)-Catalyzed Azide-Alkyne 1,3 Dipolar

Cycloaddition for Antibody-based Cancer Therapy and HIV-1 Vaccine

University of the Philippines, Manila - B.S., Biochemistry 1999-2003

Undergraduate thesis: Synthesis and Characterization of Degradable Poly(Glutaric Acid-go-glycerol) and

Poly(Malic acid-co-glycerol)

EXPERIENCE

Lecturer, Department of Chemistry, University of Washington, Seattle, January 2013 to August 2013

- Delivered undergraduate organic chemistry classroom instructions to health science and engineering majors;

developed daily lesson plan and visual aids for effective learning

- Conducted office hours to advice and tutor students

- Prepared and administered midterm and final exam, including final grades

- Courses taught include: CHEM 220, CHEM 237 and CHEM 239

Supervisor: Dr. Deborah Wiegand

Senior (Post-doctoral) Fellow, Bioengineering Department, University of Washington, Seattle. February 2011 to

June 2013.

- Designed, synthesized, characterized and biologically evaluated multifunctional peptide-based polymers using

living radical polymerization for nucleic acid delivery

- Developed and synthesized polymer-based multivalent peptide display for cancer therapy

- Synthesized and characterized small molecule linkers and modified chain transfer agents.

- Conducted and demonstrated chemical safety standards for the laboratory.

- Took charge on chemical safety and waste management for the laboratory.

- Designed projects for grant proposal as well as for graduate and undergraduate research.

- Supervised and mentored graduate and undergraduate students

Supervisor: Prof. Suzie H. Pun

Teaching and Research Assistant, Department of Chemistry, University of California at Davis, CA. September

2005 to December 2010.

- Trained in small molecule and PEG-based linkers synthesis, solid phase peptide synthesis, chromatographic

purification, and spectroscopy.

- Supervised and demonstrated techniques for undergraduate upper division organic chemistry laboratory

courses. Graded laboratory write-ups and examinations. Pre-run experiments, produced detailed protocols and

supervised new experiments for undergraduate advanced bioorganic laboratory.

- Lectured on basic organic chemistry and pharmaceutical chemistry.

Supervisor: Prof. Jacquelyn Gervay-Hague

Assistant Lecturer, Chemistry Department, De La Salle University, Manila, Philippines. May 2003 to April 2005.

- Supervised and taught undergraduate general chemistry laboratory for chemistry, engineering and arts majors.

Supervisor: Prof. Nancy Llanos

PUBLICATIONS

Chu D.S.; Schellinger J.G.; Bocek M.J.; Johnson R.N.; Pun S.H. Optimization of Tet1 ligand density in HPMA-co-

oligolysine copolymers for targeted neuronal gene delivery. Biomaterials, In press.

http://dx.doi.org/10.1016/j.bbr.2011.03.031

Schellinger, J.G.; Pahang, J.A.; Pun, S.H. Block copolymers containing a hydrophobic domain of membrane -lytic

peptides form micellar structures and are effective gene delivery agents. ACS Macro Lett., 2013, 2, 725–730.

Carlson, P. M.; Schellinger, J. G.; Pahang, J. A.; Johnson, R. N.; Pun, S. H. Comparative study of guanidine-

based and lysine-based brush copolymers for plasmid delivery. Biomater Sci 2013, 1, 736-744.

Shi, J.; Schellinger, J. G.; Johnson, R. N.; Choi, J. L.; Chou, B.; Anghel, E. L.; Pun, S. H.: Influence of Histidine

Incorporation on Buffer Capacity and Gene Transfection Efficiency of HPMA-co-oligolysine Brush Polymers.

Biomacromolecules 2013, 14, 1961-70.

Schellinger, J.G.; Pahang, J.A.; Johnson, R.N.; Chu, D.S.; Convertine, A.J.; Stayton, P.S.; Sellers, D.L.; Maris,

D.O.; Horner, P.J.; Pun, S.H. Melittin-grafted HPMA-Oligolysine Based Copolymers for Gene Delivery.

Biomaterials, 2013, 34, 2318-2326.

Wei, H.; Schellinger, J. G.; Chu, D. S.; Pun, S. H.: Neuron-Targeted Copolymers with Sheddable Shielding Blocks

Synthesized Using a Reducible, RAFT-ATRP Double-Head Agent. J. Am. Chem. Soc. 2012, 134, 16554-7.

Chu, D. S.; Schellinger, J. G.; Shi, J.; Convertine, A. J.; Stayton, P. S.; Pun, S. H.: Application of Living Free

Radical Polymerization for Nucleic Acid Delivery. Acc Chem Res 2012.

Shi, J.; Johnson, R. N.; Schellinger, J. G.; Carlson, P. M.; Pun, S. H.: Reducible HPMA-co-oligolysine copolymers

for nucleic acid delivery. Int J Pharm 2012, 427, 113-22.

Johnson, R. N.; Chu, D. S.; Shi, J.; Schellinger, J. G.; Carlson, P. M.; Pun, S. H.: HPMA-oligolysine copolymers

for gene delivery: optimization of peptide length and polymer molecular weight. J Control Release 2011, 155, 303-

11.

Wang, C. H.; Chan, L. W.; Johnson, R. N.; Chu, D. S.; Shi, J.; Schellinger, J. G.; Lieber, A.; Pun, S. H.: The

transduction of Coxsackie and Adenovirus Receptor-negative cells and protection against neutralizing antibodies

by HPMA-co-oligolysine copolymer-coated adenovirus. Biomaterials 2011, 32, 9536-45.

Schellinger, J. G.; Kudupudi, A.; Natarajan, A.; Du, W.; Denardo, S. J.; Gervay-Hague, J.: A general chemical

synthesis platform for crosslinking multivalent single chain variable fragments. Org Biomol Chem 2012, 10, 1521-

6.

Schellinger, J. G.; Danan-Leon, L. M.; Hoch, J. A.; Kassa, A.; Srivastava, I.; Davis, D.; Gervay-Hague, J.,

Synthesis of a trimeric gp120 epitope mimic conjugated to a T-helper peptide to improve antigenicity. J. Am.

Chem. Soc. 2011, 133 (10), 3230-3.

Tan, Y. H.; Liu, M.; Nolting, B.; Go, J. G.; Gervay-Hague, J.; Liu, G. Y.: A nanoengineering approach for

investigation and regulation of protein immobilization. ACS Nano 2008, 2, 2374-84.

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