Quality Control Project

Summary

V Good application knowledge of HPLC, UV/Vis Spectroscopy, GC, DSC, TGA,

Malvern Zetasizer, Karl Fischer titration, Hot Stage Microscopy,

Dissolution Apparatus

V Highly efficient in HPLC method development and validation, solubility

and stability testing using HPLC and calibration of pH meter and

analytical balances

V Knowledge of determining parameters of analytical methods like LOD,

LOQ and LOB for HPLC and UV/Vis spectrometer and mobile phase

preparations for HPLC

V Proficient in performing quality control tests for Acetaminophen

tablets which include dissolution testing, determination of content,

content uniformity, weight variation, friability and hardness

V Expertise in formulation of topical dosage forms and conducting

stability studies on them using HPLC (Waters)

V Excellence in basic computer knowledge and expertise in using MS

office (Word, Excel, PowerPoint) and worked on chromatographic data

systems (Peak Simple Chromatography)

V Excellent skills in writing Standard Operating Procedures (SOP's) and

Master Batch Records (MBR's) to meet cGMP requirements

V Expertise in performing Design of Experiments (DOE) using JMP

statistical software to optimize the formulation and manufacturing

process of a pharmaceutical product

Education

Master of Science - Pharmaceutical Sciences (Industrial Pharmacy)

May, 2013

Campbell University, Buies Creek, NC

GPA: 3.80

Bachelor of Pharmacy

May, 2011

Jawaharlal Nehru Technological University, Hyderabad, India

GPA: 3.94

Research Experience

Masters Research Project:

Title: "Study of Transdermal Diffusion of Ibuprofen from a Gel

Formulation Through Mouse Skin using Franz

Cell Apparatus"

V Dissected mouse skin, performed exvivo diffusion and collected

the diffusion data

V Formulated topical gels (Ibuprofen, Ketoprofen gels) and

conducted gel stability studies using HPLC

V Performed invitro (artificial membranes), exvivo (mouse skin)

diffusion studies using Franz cell, generated diffusion models

and calculated diffusion parameters for transdermally delivered

drugs

V Worked on HPLC (Waters), UV/Vis spectrophotometer, DSC to

analyze the results of diffusion

V Developed and validated a HPLC method for detection of Ibuprofen

and ketoprofen

V Determined parameters of analytical methods like accuracy,

precision, specificity, detection and quantification limits

(LOD, LOQ and LOB) for HPLC and UV/Vis Spectrometer

V Analyzed diffusion results using JMP statistical software and

performed ANOVA, t-test

Independent Research Project:

Title: "Formulation of Anti-herpes lipstick using Lemon-balm extract

and its evaluation"

V Extracted the juice from leaves of Lemon balm using Maceration,

Percolation and Infusion techniques

V Manufactured lipsticks using various moulding techniques

V Evaluated the lipstick formulations by DSC profiling and

determined their spread and wear qualities

Work Experience

Graduate Teaching Assistant (GTA):

Aug 2012 - April 2013

V Actively proctored and conducted labs for the undergraduates

about various concepts like cell structure and division,

genetics, ecology, evolution, western blotting, SDS PAGE/Gel

electrophoresis

V Tutored students for Biostatistics and Advanced Experimental

Design graduate level courses

Graduate Research Assistant (GRA):

Jan 2012 - May 2012

V Worked with Dr. Antonie Al-Achi, Professor, on the research

project "Study of Influence of Penetration Enhancer (d-Limonene)

and the pretreatment time on the transdermal delivery of Insulin

from a hydrophilic ointment"

V Formulated hydrophilic ointment (Insulin ointment)

V Collected diffused samples at different time intervals from

receiver chamber and performed HPLC analysis of the samples

V Performed basic analytical procedures like weighing, mobile

phase preparations, preparation of standard solutions,

pipetting, making dilutions, constructed calibration curves for

standards using HPLC

V Analyzed different factors affecting transdermal diffusion rate

and profile

Certifications

SAS Certified Base Programmer for SAS 9

July,

2012

Industrial Training Certificate

June, 2010

One month industrial training at Dr. Reddy's Laboratories Ltd,

Formulation Tech Ops-II, Bachupally, India

V Trained on handling of sifters, blenders, coating pans, driers,

tablet compression machine, capsule filling machine, hardness

testers, disintegration and dissolution apparatus

V Involved in dispensing of raw materials, processing, formulation

of various dosage forms from raw materials and their packaging

procedures

Awards and Affiliations:

V Recipient of honors "magna cum laude" with graduate degree

V Registered member of Parenteral Drug Association (PDA) South East

Student Chapter

V Active participant in AAPS (American Association of Pharmaceutical

Scientists) and PDA (Parenteral Drug Association) annual meetings

V Poster presenter at "Dravyaka", a national level seminar, on the topic

"The role of Nutraceuticals in Increasing Life Expectancy" organized

by Teja Educational Society 2010, India

V Participant in national workshop on "Green Chemistry" organized by

Jawaharlal Nehru Technological University, India

SHARANYA REDDY PERURU

1323 Langstonshire lane,

**************@*****.***

Morrisville, NC 27560

913-***-****

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