Assistant University

Husein Attarwala

****, ***** ******, *** **, Fresh Meadows, New York, 11366

******.*********@*****.***, Cell: 617-***-****.

Objective

Seeking a Chemist position in a Pharmaceutical company

SUMMARY

. Organic chemist with strong synthetic organic chemistry background

. Expertise in Retro- synthesis and multi-step organic synthesis

. Characterization of small molecule using modern analytical techniques

like NMR, LCMS and HPLC

. Expertise in purification techniques like column chromatography, UV

-Vis and gel electrophoresis

. Experience in Molecular Docking and 3D-QSAR model generation

. Experience in cell culturing and maintaining mammalian cell line

EDUCATION

Saint John's University, New York, NY

Master of Science in Medicinal Chemistry

Jun 2013

Mumbai University, Mumbai, India

Bachelor of Pharmacy

Jul 2010

SKILL SET

Chemistry: Synthesis of organic small molecules under various conditions

such as reflux, anhydrous conditions, N2 environment, etc

Chemistry Software Molecular Docking, 3D-QSAR model generation, ChemDraw,

tools: Cambridge Structural Database and Inorganic Crystal Structure

Database, Best Rx system

Analytical: Fluorescence Microscopy, Column (Size exclusion)

Chromatography, Affinity Chromatography, ELISA,, HPLC,

protein assays, in vitro assays, dialysis

Biology: Western Blot and SDS- PAGE, Cell Culture of cell lines like

T315L

Instruments and Bruker 400 GHZ NMR, GCMS, rotatary evaporator, mass

Equipments: spectrometer, Synergy HT Biotek Plate reader, Agilent HPLC, La

Chrom Elite HPLC, FreeZone freeze dryer- Labconco

RESEARCH EXPERIENCE

St John's University, Queens, N.Y

Sep 2010-present

Adviser: Professor Vijaya L Korlipara, PhD.

Dissertation Project: 8-(6-(4-(Trifluoromethyl)phenyl)pyrimidin-4-

yloxy)quinoline

. Design novel synthetic routes and perform large-scale syntheses of

quinolinoxy-pyrimidine analogs as investigational drugs for the

treatment of pain and inflammation

. Synthesize photo-affinity labels for use in determining enzyme

activity

. Design and implement an efficient system for synthesis and

purification of quinolinoxy-pyrimidine derivatives

. Run multifarious reactions including Suzuki coupling, hydrogenation,

Aldol condensations, Azide substitution reaction, Wittig reaction,

Claisen rearrangement and click chemistry

. Utilization of various purification techniques such as column

chromatography, crystallization, precipitation, distillation and

preparatory TLC

. Characterization of synthesized molecules using techniques such as 1H

NMR, C13 NMR, GCMS, IR, MS, HPLC and LCMS

. Conducted cell culturing and maintaining mammalian cell line to check

IC50 of lead molecules

. Extensively using ChemDraw for structure prediction. And using SYBYL

software for molecular modeling and generation of 3D-QSAR structures

St John's University, Queens, N.Y: Aurora Kinase Inhibitors

Oct 2010

. A detailed report on Aurora Kinase, the family of the receptors and

its pharmacology. The receptor's biological function, its expression

in the body and it's physiological role. Current clinical candidates

for aurora kinase inhibition, their chemistry and synthesis

Mumbai University: Testicular Cancer

Nov 2009

. A detailed report and presentation on testicular cancer. The report

traced the history of the disease, it's occurrence in the testicles,

highlighting the drugs currently used to treat testicular cancer and

how to overcome the disease psychologically

TEACHING EXPERIENCE

St John's University, Queens, N.Y

Pharmaceutical Health Sciences Department:

Graduate Assistant, St John's University

Aug 2012-present

. Plan and lead laboratory sessions. Assist students individually with

problems or material they find difficult to understand. Coordinate

materials, conduct lab sessions, and grade lab reports

St John's University, Queens, N.Y

Chemistry Department:

Adjunct Professor

Aug 2011-May 2012

. Instructed organic and general chemistry labs to organic chemistry

majors, physician assistants and pharmD students.

. Emphasized on the fundamentals of organic chemistry, keeping complete

and accurate scientific notes. Assist students with multi-step

syntheses of compounds

Industry Experience

Sehat Pharmaceuticals, Gujarat, India

Trainee

May 2009 - Jun 2009

. Managed chemical inventory as per Indian Pharmacopeia guidelines

. Monitored the automated manufacturing process of the liquid

formulation

. Inspected the efficiency of in-process packaging of liquid

formulations

. Monitored labeling of packaged products

. Analyzed the quality of the formulations and the drug content as per

Indian Pharmacopoeia guidelines

ACTIVITIES AND AFFILIATIONS

. Member of American Chemical Society

. Member of Indian Pharmaceutical Association-MSB: Assistant Public

Relations Officer (2009-2010)

. Assistant Cultural Secretary (2008-2009): Oriental College of

Pharmacy, University of Mumbai

. Active Participation in AIDS Awareness Drive, Co-hosting of annual

college festival throughout the undergraduate years (2006-2010)

REFERENCES

Furnished upon request

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