Downstream Associate

Associate Bioprocessing

This is an entry-level position suitable for individuals seeking hands-on experience in protein purification and quality control in an industrial bioprocessing environment. The Associate will support the downstream team in executing purification workflows and conducting protein characterization assays to evaluate product quality. Responsibilities include chromatography-based purification, recombinant protein QC related tasks under the guidance of project scientists. This role requires strong attention to detail, good lab documentation practices, and effective collaboration with cross-functional teams.

Responsibilities

Perform purification of recombinant proteins and antibodies from mammalian expression systems using chromatography methods and equipment (e.g., AKTA systems).

Execute established downstream workflows to meet project specifications and client requirements.

Conduct protein quality control testing, including SDS-PAGE, HPLC-SEC, endotoxin assays, UV-Vis concentration measurement, and other analytical assays.

Support lead scientists in preparing and analyzing QC data and interpreting protein quality results as part of downstream bioprocessing, including purification and quality control.

Maintain accurate batch records, lab notebooks, and QC documentation in compliance with internal standards and client requirements.

Ensure compliance with laboratory safety protocols and PPE usage in accordance with federal, state, and local regulatory guidelines.

Assist with calibration, maintenance, and basic troubleshooting of chromatography and analytical instruments.

Collaborate with other teams within the Center to support smooth project coordination and delivery.

Requirements

Bachelor's degree in Biology, Biochemistry, Biotechnology, or a related field.

0–3 years of relevant laboratory experience, with basic understanding of protein purification and analytical methods.

Familiarity with chromatographic systems such as FPLC or HPLC used for protein purification.

Experience or exposure to protein QC analytical assays, such as SDS-PAGE, HPLC-SEC, and endotoxin testing and ELISA.

Strong organizational and documentation skills, with attention to detail.

Willingness to work a flexible schedule, including early/late weekday shifts and occasional weekend work depending on project needs.

Good communication skills and a collaborative team mindset.

Flexibility is required, including potential weekend work and early or late weekday shifts based on project demands.

Must be able to lift and move 25–50 lbs as needed.

At this time, we are unable to provide visa sponsorship. Applicants must be legally authorized to work in the United States now and in the future without the need for sponsorship.

Why Join Us at C4B?

World-class location: Be part of the Texas Medical Center, the largest medical complex in the world, where biotech innovation thrives.

Beautiful work environment: Enjoy a brand-new, state-of-the-art facility designed for collaboration and scientific excellence.

Free onsite parking: Skip the hassle and expense of parking in the Medical Center — we've got you covered.

Free onsite gym: Stay active and energized with convenient access to fitness facilities right at work.

Career growth opportunities: Learn directly from industry professionals while growing your career at a global biotech company.

Supportive team culture: A welcoming, team-first workplace that values diversity, collaboration, and professional development.

Sino Biological Inc. is an equal-opportunity employer. We celebrate diversity and are committed to building an inclusive environment for all employees.