Position Good This

SAMUEL N KIKANDI, PhD

(ANALYTICAL CHEMISTRY)

Mailing Address: 19 Laurel Avenue, Binghamton, NY13905;

Cell Phone: 607-***-****; Email: *************@*****.***.

Applying for the Senior Analytical Development/Validation

CURRENT SPECIALIZATIONS: High Performance Liquid Chromatography (HPLC) & Size Exclusive Chromatography (SEC) operated by EMPOWER 2/PRO.SOFTWARE; Ion Chromatography(IC) operated by DIONEX Chromeleon SOFTWARE and Gas Chromatography (GC) operated by CHEMSTATION SOFTWARE and related Chromatographic works

CURRENT POSITION (JUNE 1, 2010-PRESENT)

SENIOR SCIENTIST-LANCASTER LABS UNDER PROFESSIONAL SCIENTIFIC STAFFING (PSS) AT SONOFI PASTEUR, SWIFTWATER, PA

AWARDS FROM CURRENT EMPLOYER LANCASTER LABS, PA)

• Received individual Impact/superlative AWARD PSS from site supervisor & Director for developing a vaccine residual testing method with 20-fold lower LOQ better than client’s existing method within 2 weeks on a 5 weeks’ timeline assignment ( Lancaster labs news: The Beaker September 2011, vol.XXV no. 9)

• Received a team Impact/superlative AWARD from the Director PSS, Lancaster labs, for meeting client company needs and time lines during vaccine residual testing (Lancaster labs news:The Beaker, February 2011, volume XXV No.2)

KEY ANALYTICAL PHARMACEUTICAL /INSTRUMENT SKILLS:

• METHOD DEVELOPMENT for API and residual compounds and drug substances in accordance to GXP: Problem solving- literature search, experiment design, data interpretation, written and oral data presentation

• HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-UV/ OPERATED BY EMPOWER SOFTWARE/ Applications to quantitation of vaccine active ingredient and stability studies in support of manufacturing

• HIGH PERFORMANCE ANION EXCHANGE CHROMATOGRAPHY-PULSED AMPEROMETRIC DETECTION/OPERATED BY Dionex Chromeleon SOFTWARE /Applications to polysaccharide-protein vaccines testing

• SIZE EXCLUSIVE CHROMATOGRAPHY(SEC) /EMPOWER SOFTWARE/Applications to vaccine potency/stability/aggregations studies

• GC-FID/Chemstation SOFTWARE for quantitation of vaccine residuals

• Accurate Lab Note Documentation in compliance with SOPs & Standard Working Instructions(SWIs)

• Computer skills: Excel, Ms word, PowerPoint, dry lab (for HPLC), data entry (LABWARE/LIMS)

• Some AFT-IR, LC-MS, fluorescence, NMR & Electrochemical skills from Academia : specific applications in monitoring anti-oxidants in simulated physiological media (see resume for various peer reviewed publications)

ACADEMIC QUALIFICATIONS

PhD in Analytical Chemistry, State University of New York, at Binghamton, NY, 13902. Dissertation Title: Understanding the Mode of action of Estrogenic Compounds and Development of Novel Electroless Plating methods

College Teaching Certification 2008, State University of New York, at Binghamton, NY,13902

• MS in Analytical Chemistry (GPA 3.8/4.0), Moi University, Kenya.

Thesis Title: A study of heavy metal contamination in honey from Keiyo, Marakwet and Mount Elgon districts of Kenya, 2002.

• Postgraduate Diploma in Education (GPA 3.8/4.0), Egerton University, Kenya, 2002. Program involved developing teaching methods, curriculum, administration & management, assessment & school syllabus implementation.

• BS (Chemistry major), Egerton University, Kenya, 1996

SELECTED ACHIEVEMENTS

JUNE 1, 2010-PRESENT (2012):

AS A SENIOR SCIENTIST AT LANCASTER LABS PSS at Swiftwater site, PA

• Been successfully running Size Exclusive Chromatography(SEC) for vaccine drug substance stability studies

• Been successfully supporting vaccine testing on tight timelines and quick turn rounds by Reverse Phase HPLC.

• Successfully trained new Lancaster PSS employee, on Reverse Phase HPLC for vaccines testing works

• Developed a new HPLC-AEC method for a vaccine residual & received a Superlative Award from Site Supervisor & Director of Professional Scientific Staffing (PSS), Lancaster labs, PA ( Lancaster labs news: The Beaker September 2011, vol.XXV no. 9). Also received congratulatory phone call from the Lancaster President through the Director of PSS. The HPLC method ran for 7 minutes at the time of the award and had LOQ of 20-fold lower than an existing HPLC method. The development took 2 weeks on a 5 weeks’ timeline and met client satisfaction. The method was later improved to 40-fold LOQ and more work is going to finalize it for future transfer to QC

• In a separate work, I improved another client’s existing HPLC method for separating two monosaccharide components by more than 50 % run time within my 3 months of employment. The method Chromatograms showed peaks resolution improvement of more than 100 % and better accuracy.The method is yet to be validated for future applications.

• In collaboration with others, I personally generated quantitation & stability method for monovalent drug substances that was eventually adopted by the group for further development. Soon expecting co-authoring of a Standard Work Instruction (SWI) procedure for this form of drug substance for future transfer to QC

• Successfully executed Gas chromatography-FID testing as primary analyst in support of vaccine production as per Standard Working Instructions (SWI) under cGMP environment.

• Been successful in executing computer softwares such as Chromeleon for HPLC-Anion Exchange-Pulsed Amperometric Detection, Chemstation for GC-FID , Empower for Reverse Phase HPLC, Excel, Ms word, PowerPoint, data entry lab ware/LIMS

SELECTED ACHIEVEMENTS AT GRADUATE SCHOOL/ACADEMIA

• Successfully operated and utilized technical skills from various instruments including but not limited to GC-MS, LC-MS, UV-VIS, fluorescence, & Electrochemistry. Some works from these skills resulted in peer-reviewed publications in high impact journals which included the following:

(i) American Chemical Society-Environmental Science & Technology

(ii) Journal of environmental monitoring,

(iii) Journal of electrochemical society ,

(iv) Electroanalysis Technology

(v) Electrochemistry communications,

WORK HISTORY & AWARDS

June 1, 2010-Present: Senior Scientist working for Lancanster labs under professional Scientific Staffing at Sanofi Pasteur, Swiftwater, PA 18370.

June 2008-February (2010):

• Worked as postdoctoral fellow after receiving a postdoctoral Fellowship Award from the United States Environmental protection Agency (US-EPA) as a recent graduate/Student Contract Services at the State University of New York at Binghamton, NY13902.

• The contract ran for 1 years ending in February 2010. It involved development of novel detection methods for detecting engineered nanomaterials arising from the emerging Nano technological science

2005-April 30th, 2008:

• Worked as a Research Assistantship (RA) with RA award from my advisor while working towards my PhD at Binghamton University.

• Mentored ten students and four of them graduated with honors under my supervision. Some of these students co-authored peer reviewed papers with me.

2002-2004: Teaching Assistantship (TA)

• Received TA scholarship award & acceptance to graduate school from the state University of New York at Binghamton NY 13902.

• While on this scholarship I developed teaching methods for undergraduate students at freshman, sophomore and senior levels in chemistry courses mainly conducting Lab Sessions, grading Lab reports and examinations. The course taught included general chemistries I & II, Introduction to analytical chemistry theory and practice and Instrumental methods of analysis

1997-2002: Full Tuition Scholarship & Partial Research Scholarship in highly competitive MS degree at Moi University, Eldoret, Kenya

PUBLICATIONS

(1) Omowunmi; Kikandi, Samuel; Wang, Qiong; Varner, Katrina; Burns, Sarah. Size-exclusive Nanosensor for Fullerene C60: A Conceptual Approach( ES & T, Accepted, in Press, 2011)

(2) Sadik.O.A; Kikandi.S; Wang.C.Q; K.Varner. Sensors as tools for quantitation, nanotoxicity andnanomonitoring assessment of engineered nanomaterials. Journal of environmental monitoring 2009, 11,1782-1800.

(3) A. Zhou, S.N Kikandi, O. A. Sadik, “Electrochemical Degradation of Quercetin: Isolation and Structural Elucidation of the Degradation Products”, Electrochemistry Communications 9 (2007) 2247–2256.

(4) S. Kikandi, J. Brito, O. A. Sadik, “Electroless Deposition of TiO2/Ti onto Aluminum Substrates”, J.Electrochem. Soc. 154, D346 (2007).

(5) S. N. Kikandi, S. Musah, K. Lee, J. Hassani, S. Rajan, A. Zhou and O. A. Sadik. “Comparative Studies of Quercetin Interactions with Monophosphate Nucleotides using UV-Vis Spectroscopy and Electrochemical Techniques” (Eectroanalysis 19 (19-20): 2131-2140 OCT 2007)

(6) O. A. Sadik, S.N. Kikandi, J. Karasinski, M. Ogunlesi, W. Okiei, O. Oyewo, Novel Chemical Database for Monitoring the Marine Environment, PhD Dissertation, 2008, Chapter. 8, p.218-260.

(7) S. N. Kikandi.; J. Hassani., and O.A. Sadik, Novel multi-layer electroless deposition of Ni, Au and Cu on silvered polyimide substrates PhD Dissertation,2008, Chapter. 7, p.193-218

SELECTED CONFERENCE PUBLICATIONS/PAPERS (20+ PAPERS)

(1) Wunmi Sadik, Kikandi S., Wang.C., Varner. E. K. Sensors as tools for quantitation and cytotoxicity studies of engineered nanomaterials Department of Chemistry SUNY-Binghamton, NY, NEMC San Antonio, Texas, August 10-14, 2009

(2) VARNER, K. E., S. Kikandi, AND O. A. Sadik. The Latest Emerging Contaminant: Nanomaterials as Personal Care Products and Their Environmental Impact. Presented at Society of Environmental Toxicology and Chemistry, New Orleans, LA, November 19 - 23, 2009.

(3) VARNER, K. E., S. Kikandi, AND O. Sadik. Fullerene Nanoparticle Counter Using Quartz Crystal Microbalance. Presented at 2009 EPA Nano STAR Grantee Meeting, Las Vegas, NV, November 09 - 11, 2009

(4) Sadik, Wunmi; Kikandi, Samuel; Qiong, Wang; Varner, KATRINA. Novel sensors for the identification and quantitation of engineered nanomaterials in environmental matrices.Goteborg, Sweden, SETAC Europe 2009.

(5) S. N. Kikandi, Q. Wang, O. A. Sadik,K. E. Varner.Novel sensors for quantitation and cytotoxicity of selected nanomaterials.237th American Chemical Society national meeting & Exposition, Salt Lake City, UT, March 22-26, 2009

(6) S.N Kikandi -Presider oral Session 1100, Environmental Samples and Preparation II Tuesday Morning, Room 236 on behalf of Prof. Omowunmi Sadik of the State University of New York, Binghamton (Pittcon), New Orleans, Louisiana, 2008

(7) S.N Kikandi, A.Zhou, S.Musa, J.Romulus, John hassani. “Comparative Studies of Quercetin Interactions with Monophosphate Nucleotides” (Pittcon), New Orleans, Lousiana, 2008

(8) Ailing zhou, Samuel N Kikandi, Omowunmi A Sadik.”Electrochemical Degradation of Quercetin: Isolation and Structural Elucidation of the Degradation Products”. Pittcon), New Orleans, Louisiana, 2008

(9) Ailing Zhou, Samuel N Kikandi and Omowunmi A Sadik. “Understanding the Cytotoxic Effects of Quercetin on Cancerous Cells”, (Pittcon), New Orleans, Lousiana, 2008

(10) S.N Kikandi, Samira Musah, Joy Romulus, Ailing Zhou, Austin Aluoch. “Monitoring the Interactions of Quercetin with Nucleic Acids” (Pittcon-ACS Division), New Orleans, Lousiana, 2008

PLUS

MORE THAN 10 OTHER CONFERENCE PAPERS

UNDERGRADUATE RESEARCH & MENTORSHIP

Mentored ten undergraduate students towards independent studies and four of them graduated with Honors thesis. These are:

(1) Samira Musah, Honors thesis 2006 “Electrochemical and Spectroscopic Studies

of Real Time Quercetin Oxidation Products and the Interaction with Biomolecules”

(2) Joy Romulus, Honors Thesis 2006, ‘Electrochemical Characterization of Endocrine Disrupting Chemicals”

(3) John Hassani, Honors thesis 2008, “Multilayered Metallization of Polyimide

using Electroless Deposition”

(4) Fenix Garcia Tigreros, Honors thesis 2009, “Towards the Development of

Electrochemical Sensors for Detecting Silver and Fullerene Nanoparticles”

VOLUNTEER ACTIVITIES

• Community Education for 9th graders at Binghamton NY(2011-2012)

• Voluntarily Participated in a local elementary school committee, Family Enrichment Network, Johnson City, NY 13790 (2007/2008)

• Successfully, organized and examined High school students from the local community at SUNY-Binghamton, NY, Science Olympiad 2006;

• Helped coordinate and organize meetings at SUNY-Binghamton during the Destination Discovery 2005;

• Organized, Improved and created Lab Chemical Inventory Database including purchases and records in Professor Sadik’s Lab 2003-2006.

LEADERSHIP

• Administrative: Laboratory Manager- ordered lab equipment and supplies including installation and performance testing of Potentiostats, UV-Vis, GC-MS, multi-hazard controlled atm. Glove box and other major instrumentation.

• Treasurer: Planned, organized and held the Graduate Chemistry Club activities, SUNY-Binghamton 2005

• Treasurer: Successfully managed and coordinated funding for scholar and get together activities for the Graduate African Students Organization (GASO) 2005/2006

REFEREES

1. Omowunmi A. Sadik,

(Dissertation advisor)

Professor, Bioanalytical and Environmental Chemistry; e-mail: ******@**********.***

Phone: Office: 607-***-****, Lab: 607-***-****; Fax: 607-***-****

2. Jason Karasinski, Deputy Director, AP & T Sanofi Pasteur, Swiftwater PA; Cell phone: 570-***-****

3. Mike Ando,

Deputy Director, AP &T,

Sanofi Pasteur, PA

Contact this candidate