Experienced Bioanalytical Scientist

Shannon Ludascher

*** **** ****** ***. ***

West Conshohocken, PA 19428

*******.*********@*****.***

215-***-**** ______________________________________________________________________________________________________

Objective:

To work in an environment that embraces motivation, enthusiasm and accomplishment

Education:

Bachelor of Science in Forensic and Toxicological Chemistry

West Chester University – West Chester, PA: May 2006

University Coursework:

Analytical Chemistry Forensic Chemistry Microbiology

General Chemistry I and II Toxicology Biochemistry

Organic Chemistry I and II Recombinant DNA Calculus based Physics I and II

Descriptive Inorganic Chemistry Genetics Literature of Chemistry

Physical Chemistry General Biology Technical Writing

Industrial Coursework:

Restek Comprehensive HPLC training seminar, LCMS training seminar

Instrumentation and Laboratory Experience:

HPLC/MS/MS GC/MS ELISA

(API 365, API 4000, API 4000QTrap, (Hewlett Packard #5890 Gel Electrophoresis

API 5000, Cohesive ARIA TX-2) MSD #5970 Series I and II) PCR

LEAP HTS PAL and Shimadzu Autosamplers Tecan Robot (Genesis RSP 200) 60 and 300MHz 1HNMR

Computer Skills:

Analyst Software Microsoft Excel Microsoft PowerPoint

Chemstation Software Microsoft Word Lotus Notes

Professional Experience:

GlaxoSmithKline, Assistant Scientist, Quantitative Bioanalyst

King of Prussia, PA, August 2006-Present

•Quantify NCE’s for various in vivo and in vitro DMPK assays

•Develop high throughput and sensitive methods on HPLC/MS/MS systems

•Analyze in vivo pharmacology samples to confirm exposure

•Generate calibration standards for quantitative analysis

•Trouble-shoot and maintain various LC/MS/MS systems

•Reduced typical analytical run-time from 3.5 minutes to 1.5 minutes by validating and implementing a generic fast chromatographic method

•Approved analytical results of other analysts for high throughput microsomal intrinsic clearance studies

•Presented to and participated in literature discussion group and bioanalytical focus group

PA Equine Toxicology and Research Lab, Intern, Screening and Confirmation

West Chester, PA, Summer 2005

•Assisted in the method development and identification of a new drug discovered in the PA horse-racing industry in less than 12 weeks

•Received, organized, prepared and analyzed 50-100 blood and urine samples from purse-winning horses daily

•Conducted immunoassay screening tests using ELISA test kits for over 48 drug classes and metabolites

•Operated the robotic liquid handler, Tecan Robot (Genesis RSP 200), in order to increase work time efficiency

•Routinely prepared and tested post-mortem tissue samples for drug content

•Conducted qualitative analysis for drugs and their metabolites using GC/MS for identification and verification

•Documented conclusions in written reports for supervisor and PA state records

•Responsible for routine GC/MS maintenance, including the daily instrument tune, column testing and replacement, and weekly cleaning

National Foam Division, Kidde Fire Fighting, Intern, Research and Development

West Chester, PA, January – May 2006

•Determined the effectiveness of foam concentrates in fire extinguishment

•Increased clientele by demonstrating product functionality designed for customer’s specific needs

•Acted as interim quality control manager, responsible for the oversight of a staff of 3 technicians and issuing final approval for all products

•Carried out physical property testing on final foam products to comply with municipality and government requirements

•Maintained sample logs for traceability, inventory and future reference

Friendly’s Ice Cream Corporation,

Waitress/Supervisor/Keyholder

PA March 1999 - August 2006

•At the age of 18, was one of the youngest staff members to hold a supervisory position

•Managed a staff of 15-20 employees in varying positions in the restaurant

•Worked 20-30 hours/week while carrying a full course load to pay for tuition

Awards:

•Received a Silver award from GSK CVU CEDD DMPK in February 2008, and a Bronze award in August 2007

•Finished first place in the student competition at the 2005 Northeastern Association of Forensic Scientists Conference

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