Synthetic Organic / Analytical Chemist

Praveen Bachawala

**** ****** **. #** **********@*****.***

Cincinnati, OH 45220 513-***-****

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Highlights:

• PhD in Synthetic Organic / Analytical Chemistry

• Eight years of experience with a wide variety of synthetic organic and analytical techniques in characterizing small molecules

• Technical expertise in separations, purifications, and product identification using modern spectroscopic techniques like: NMR, 2D-NMR, IR/FTIR, UV, UV/Vis, Florescence Spectroscopy, GC/FID, GC/MS, HPLC, LC/MS, ES/MS, pH meter, TGA, Karl Fisher and MALDI

• Trained in cGMP environment

• Working knowledge in performing “Dissolution, Impurities Assessment, Excipient Compatibility of API’s & commercially manufactured drug samples, Method Development, Validations & Cleaning Validation using HPLC.

• Gained industrial experience as a Ph.D intern at Solvay, Procter & Gamble and Patheon Pharmaceuticals

• Successfully wrote proposal, presented research at ACS and was awarded funding from ACS and University Research Council to perform research

• Critical thinker, self- starter, effectively collaborated in past with cross functional teams and innovated new methodologies to address customer needs

Patents & Book Chapter

• Host Material for Light-Emitting Diodes – Patent number – EP 2206716 (A1)

• Host Material for Light-Emitting Diodes – Patent number – WO2010043693 (A1)

• N-Phenyl Carbazole-Based Host Material for Light-Emitting Diodes – Patent number – WO2010043691 (A1)

• Co-author of a book chapter entitled “Fragments of Fullerene and Carbon Nanotubes”. Publisher: Wiley

Professional Experience:

Patheon Pharmaceuticals Summer Intern – Analytical Development (2011)

• Provided analytical support to formulations groups by examining “Excipient Compatibility, Stability Assessment, Dissolutions, Content Uniformity, Assay” for both commercial and in-house manufactured drugs via HPLC

• Performed method validation along with method development, Method transfers and Cleaning Validations to analyze pharmaceutical products via HPLC

• Reviewed & revised SOP’s, methods to accurately meet cGMP and FDA regulations

• Familiar with Agilent based chromatographic instrument.

P&G Ph.D. Summer Intern – Beauty & Grooming, R&D Division (2010)

• Designed and executed the synthesis of key couplers used in hair dyes from sustainable sources

• Successfully optimized key steps for selectivity with increased output employing milder reaction conditions

• Published two internal publications (SLRs) enlisting key developments

• Applying for a patent which describes robust and most economical way to synthesize key couplers from sustainable sources to support claims department

University of Cincinnati, OH – Graduate Student (2006 – present)

• Successfully functionalized corannulene’s outer rim at 1,8/1,5 and 1,2,7,8 positions and coupled with phenyl, anthracene and corannulene motif’s using sonogashira coupling chemistry

• Independently optimized the existing synthetic pathway for best yields

• Examined photophysical (absorbance, fluorescene and laser excitation) properties of target molecules for possible applications as blue emitter in OLED technology

• Computationally modeled target molecules to study optimized geometries and orbital transitions

• Currently synthesizing “enediyne-cornannulene derivatives” for possible use as a contrast agent in MRI applications

Solvay Ph.D. Summer Intern – OLED R&D Division (2008)

• Independently designed and synthesized highly efficient N-Phenyl carbazole based blue - OLEDs

• Regioselectively functionalized the carbazole moiety, optimized key steps, accomplished separation and characterized target molecules using HPLC, NMR, GC/MS

• Published three patents enlisting synthesis and photophysical properties

Mississippi State University – Graduate Student (2003-2006)

• Carried out multi-step, large scale synthesis of corannulene

• Designed a robust and benign dehydrohalogenation methodology using Palladium chemistry for catalytic reduction of tetrabromocorannulene to corannulene

• Synthesized novel derivatives of corannulene using C-C, C-O coupling chemistry employing Suzuki and Heck reactions

Education:

• Ph.D. student (2006-present), University of Cincinnati, Ohio

Thesis title: “Understanding conjugation and substituent effects over corannulene for its application in blue OLED”

Advisor: Professor James Mack

• M.S. Organic Chemistry (2003-2006), Mississippi State University, Mississippi

Thesis title: “Large scale synthesis and derivatization of corannulene – The Smallest Buckybowl”

Advisor: Professor Andrzej Sygula

Honors and Achievements:

• Outstanding Research Poster Award at PINO Conference – Case Western Research University (2011)

• GSGA Research Award - University of Cincinnati (2011)

• Division of Organic Chemistry – ACS – Travel Award to present research at National ACS conference, Boston (2010)

• Henry Hochstetter award for excellent performance as best graduate teaching assistant (2010)

• Housing & Living Expense award by P&G (2010)

Selected Presentations:

• Oral presentation at ACS National Meeting 2010, San Francisco, CA- “Development of Corannulene-Based Blue Emitters”- Praveen Bachawala, James Mack

• Oral presentation at ACS Regional Meeting 2010, Dayton, OH - “Synthesis and Photophysical Properties of Corannulene Based Organic Materials” - Praveen Bachawala, James Mack

• Oral presentation at ACS National Meeting 2010, Boston, MA- “Corannulene Based Blue Emitters” – Praveen Bachawala, James Mack

Teaching & Leadership Experience:

• Organic chemistry undergraduate laboratory – Teaching Assistant (2006 - present)

• Organic chemistry undergraduate laboratory and recitation – Teaching Assistant (2003 – 2006)

• Managed undergraduate (8) and graduate students (2) in lab

References: Available on request.

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