Syed Zahid R. Kazmi

** ******* **** ****, ******, CA-91766 r93t9j@r.postjobfree.com 610-***-****

Summary of Qualification

• Worked in Integrated Product Development (IPD) for Ethicon-sponsored medical device project design (Debridement of Necrotic Tissue). Experiences included patent research, conception, design, prototype, design analysis, business & financial feasibility studies, and presentation to Ethicon and Lehigh faculty. Efforts were made to address patient’s concerns and end-user’s needs.

• Research experiences in biomedical design, engineering, biomaterials, nanotechnology, & Cancer Research publication (manuscript submitted to the Journal of Molecular Imaging 2011). Strong mechanical and biomedical aptitude.

• 10+ months of customer correspondence experience including technical & analytical aspects, product support, quality, and performance. Experienced with documenting and investigating customers’ complaints and addressing their needs with regular follow ups. Experienced with the understanding of possible product quality failures and implementation of solutions to rectify them.

• 20+ months of adhesive application experience in manufacturing and PVC Thermofoil processing.

• Familiarity with the workings of MS Office, Solidworks, Instron, Statistical Software, & Failure Mode Effects Analysis (FMEA)

• Strong knowledge of Biology, Chemistry, Physics, Engineering, Statistical Analysis, & acquaintance with basic knowledge of Documentation, FDA, Good Laboratory Practice (GLP), Good Manufacturing Practice (GMP), & different biological lab techniques (Electrophoresis, ELISAs, Flow Cytometry, Cell Culture & Media, Basic Lab Aseptic Techniques).

• Worked in establishing, documenting, and maintaining Standard Operating Procedures (SOPs) for PVC Thermofoil Processing, Packaging and Equipment Validation.

• Excellent writing, analytical, presentation, & communication skills. Ability to work independently and lead in teams.

• Internships and volunteer experience at hospitals and interactions with patients, physicians, surgeons, and nursing staff.

Education

Master of Science (MS) – Biomedical Engineering Florida International University, Miami-FL Dec 2009

GPA: 3.60; Post-Bac GPA: 3.90

Bachelor of Science (BS) – Bioengineering Lehigh University, Bethlehem-PA May 2007

GPA: 3.35

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Internships

Pharmaceutics International Inc., MD, USA June-July 2007

Observed and participated in key steps of cGMP manufacturing of SoftGel pharmaceutical drugs that included compounding, gelmass, encapsulation, drying, inspection, sorting, and bulk packaging

Learned to document key cGMP procedures such as Cleaning Test Result (CTR) and Master Batch Record (MBR)

Participated in Formulation lab and worked on instruments such as Texture Analyzer, Brookfield Rheometer (Viscometer), Moisture Analyzer

The Kidney Centre Hospital April-May 2003

Observed and learned different modes of treatment for kidney disordered patients such as dialysis, lithotripsy, and catheterization

First Aid Medical Camp 2000-2002

Learned the fundamental methods of wound care from cleaning to stitching

Work Experience

BRR LTD. CO., PA, FL, & NJ (Thermo-foil Processing Unit) August 2009-to present

Assistant Process Engineer

● Assisted in setting up new machine design, installation, operation and marketing of Pre-applied thermo-foil products.

● Assisted in establishing new facility and process to apply PUR Extruded HOT-Melt adhesive on Extruded and Calendared PVC/ PVC/ Polyester/ Textile - wide width films, through deadline of 6 months. (Pre-Applied Decorative Thermo-foil/ Sew-free Garments)

● Assisted in designing quality control system by implementing new procedures in processing and packaging to improve quality and reduce waste/cost

● Laid down proper Roll handling and packaging procedures for short term and long term storage to increase Product Shelf Life.

● Travelled to New Jersey and Florida branches back and forth troubleshooting production shortcomings, managing technicians, and exploring new business prospects.

● Responsible for handling customer field-related complaints, concerns, and corrections.

● Assisted in documenting, analyzing, and rectifying the root cause of production/manufacturing problems and maintaining customer relations and product quality.

Accomplishments:

● Reduced customer complaints and returns by 35% and established company’s reputation as one of the best thermo-foil processing companies in the United States.

● Assisted in increasing business activity/Revenue by 8%/ by introducing additional business line in collaboration with Japanese Company.

● Established Short-Roll Program.

● Established & maintained SOPs; Validation & Documentation process for assurance of consistent defect-free production

● Started as a student observer at BRR and progressed over couple of months to the current title while pursuing education as a full time student.

Project Experience

Fluorescence Imaging & Hyperthermia Set-Up May 2008-Aug 2009 (MS Research Project-Florida International University)

The project’s primary objective is to deliver cancer curing drug (Doxorubicin) in a more effective way in order to minimize drug toxicity such as lethal effects on heart chambers and muscles

Broader objectives comprise of using nanoparticles as vectors for drug (Doxorubicin) administration in order to increase drug specificity; inducement of hyperthermia for effective deletion of cancerous cells; and fluorescent- based CCD (charge-coupled device) camera imaging

Studied in-vivo imaging and tracing of Indocyanine Green (ICG) fluorescent dye inside the rat which was possible by exciting the dye using a low power (80 milli Watts) 785 nm wavelength laser

Compared different modes of treatment being studied such as hyperthermia, nanoparticle-administered drug delivery, Doxorubicin, and ICG and analyzed their synergistic effects

Accomplishments:

Upgraded the software and corrected old and flawed imaging system incapable of producing desired images by replacing the low band pass filters with that of high ones which resulted in increased signal-to-noise ratio and better images

Contributed in performing comparative study of InfraRed (IR)-820 and ICG: Optical Properties, in vitro Stability, Cellular Uptake, and in vivo Stability. Manuscript in preparation, to be submitted to Journal of Molecular Imaging

Debridement of Necrotic Tissue Sponsored by Ethicon, Subdivision of Johnson & Johnson Jan-Dec 2006 (Integrated Product Development-Lehigh University Capstone Project)

Worked on Lehigh’s Integrated Product Development project for one year related to debridement (removal of dead, damaged, or infected tissue)

Researched field of debridement in collaboration with physicians & nursing staff and designed various ideas for new procedures such as approaching the analyzing the synergistic effect of mechanical (pumping) and chemical (ointment) treatments.

Engineered final working prototype; and presented to the company sponsor and Lehigh faculty which resulted in a positive consideration of this project

Developed financial feasibility skills, produced cash flow model, and sensitivity analysis based on projected scenarios

Analyzed break-even point, go/no-go investment decision points, evaluated Net Present Value and Return on Investment, and analyzed sensitivity of the project

Analysis of Infants’ Cartilage Fall 2006 (Thesis-Lehigh University)

Worked on histological computer images of infants’ Eustachian Tube, ET (ear) suffering from the disease Otitis Media

Using MetaMorph computer software analyzed images obtained from the Department of Pediatric Otolaryngology, Children’s Hospital of Pittsburgh and calculated area of cartilage in the ET; studied and compared the sizes of cartilage among patients and normal infants and concluded that diseased cartilages are different from the normal ones

Design and Validation of Bird-Flu Isolator Spring 2006 (Senior Design Project-Lehigh University)

Proposed quarantine design (isolator) for Bird-Flu Influenza A Virus Subtype H5N1 infected patients

Efforts were made that all the design plans and validations comply with Food and Drug Administration (FDA’s) Current Good Manufacturing Practices (cGMP) specifications

Explained procedure for validating Bird-Flu Isolator emphasizing the use of fluorescent dye and flow cytometer through the exhaust system

The design incorporated UV light system for proper neutralization of harmful microbes at the exhaust point

Research Publication 2009-2011

Fernandez-Fernandez A, Manchanda R, Lei T, Carvajal DA, Tang Y, Raza Kazmi SZ, McGoron A. (2011). A comparative study of optical and heat generation properties of IR820 and Indocyanine Green. Submitted to Molecular Imaging, in review

Computer Skills

*SolidWorks Office Premium * Matlab *QuickBooks *Minitab Statistical Software *Microsoft Excel *Microsoft Word *Comsol Multiphysics *DOE (Design of Experiments) Statistical Software *MetaMorph

Awards and Affiliations

(1)Leadership & Annual Pride of Performance Awards presented at Habib Public School, (2) Florida International University, The Honors College Recognition 2008 (3) Lehigh Carbon Community College (LCCC), Dean’s Honor List Recognition, Fall 2004 (4) Teachers’ Resource Centre Award of Appreciation for organizing Recreational Events (5) Friends of Anti-Narcotic Appreciation Award (6) Magna Cum Laude Recognition, The National Scholars Honor Society, Spring 2009

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