Technician Maintenance

MICHELE ANN TURNER

Boston, MA

LinkedIn Profile | email: ***************@*****.***

ANALYTICAL CHEMIST

Analytical Chemist, utilizing many techniques, excellent communication (verbal and written), technical writing and documentation skills, continuous independent study/research of instrumentation, methods and scientific topics to advance knowledge, conversational Spanish. Key skills include:

Expertise in ICP-AES Varian 725ES with Expert II software, TriStar BET Physisorption and Surface Area Analyzer, Malvern Mastersizer Particle Analyzer

Chromatography: HPLC (Agilent and Waters) with ChemStation, Detectors: ELSD, PDA, and RI

Spectroscopy: FTIR (Perkin-Elmer), UV-Vis

Thermal Analysis: TGA (TA instruments/Universal Analysis Software),

Moisture Analysis: Karl-Fisher Titration and, Varian Moisture Analyzer and VTI Sorption/Desorption Analyzer and MDSC

Exposed to: Karl-Fisher Turbo2, Dissolution Apparatus with on-line UV-Vis

Computer Experience: Microsoft Word, Excel, PowerPoint and Publisher

Graduate work in Chemistry: *Research Completed*

University of Massachusetts-Boston 2000-2004

Bachelor of Science in Chemistry

Bridgewater State College 1993

EMPLOYMENT HISTORY

ANALYTICAL CHEMIST

Sud-Chemie, Inc. Needham, MA 5/ 2008-10/2009

• Provide analytical testing for Production, Engineering, QC, Sales and Customer Testing pertaining to company’s development and manufacture of precious metal catalyst

• Assist R&D with special projects for the innovation of materials and applications.

• Operation, optimization, maintenance and troubleshooting on the following instruments: Varian ICP-OES 725ES (Expert II software), Micromeritics BET Tri-Star Physisorption with SmartPrep, Malvern Mastersizer 2000 Particle Sizer and Malvern C-VOR 150 Rheometer (Bohlin software) using cone and plate and parallel plate, Mettler-Toledo Densito PX30 densomiter

• Method development and method transfer with instrumentation

• Microwave digestion of metals into solution for analysis by ICP-OES

• Monitor precision and verification of all processes/methods via metrics and trends

• Schedule preventive maintenance and service calls with instrument vendors, schedule demonstrations to determine necessity and/or feasibility of purchasing new equipment/instruments

• Communicate with technical support regarding optimal sample prep methods and technical, theoretical and software experts on all instruments

• Research team member in on-going viscosity projects with production, engineering and R&D

• Write SOP’s and reports for justification of specification changes of product measurement ranges and/or need for method changes/redevelopment.

• Analyze and examine damaged returned materials from the field and submit report of findings to management and customers

• Trained and certified Internal Auditor. PPAP and FMEA trained. Use LIMS and LORT systems.

MICHELE ANN TURNER p. 2

EMPLOYMENT AS CONTRACTOR 2004-2007

APPLICATIONS CHEMIST

Waters Corporation, Inc. Milford, MA (10/2007-12/2007)

• Developed methods for troubleshooting HPLC instruments such as problems with injectors, columns etc. using fraction collections.

• Routine maintenance of instrument and optimization to evaluate methods developed

ASSOCIATE SCIENTIST II

Vertex Pharmaceuticals, Inc. Cambridge, MA (4/2007-8/2007)

• Prepared and evaluated formulations and suspensions for pre-clinical studies

• Experience with DSC and MDSC for characterization of compounds and stability testing

• Particle size analysis using Malvern Mastersizer

• Solubility and purity evaluation of compounds in early research stages and those in development using HPLC-DAD

• Exposed to Karl-Fisher Turbo2 Moisture Analyzer for moisture analysis of solid state compounds

• Prepared toxicity vehicles for pre-clinical studies and prepared various inactive ingredient mixtures for API’s in development.

• GC-FID small molecule purity evaluation

PRINCIPAL SCIENTIST, ANALYTICAL DEVELOPMENT

GSK-Biologicals Northborough, MA (8/2006-9/2006) (permanent position, site closed)

• Hands on experience with HPLC coupled with Photo Diode Array Detection (PDA) and Evaporative Light Scattering Detection (ELSD) Performed assay qualification procedures to evaluate precision, accuracy, and linearity of developed assays.

• Conducted in process and release testing for protein vaccine products, including % purity, and residual detergent analysis. Helped to develop a spectrophotometry method for detection and quantification of residual EDTA in final bulk drug substances

• Trained in operation and maintenance of Inductively Coupled Plasma for analysis of trace metals in bulk drug substances and assisted in development of method and SOP for ICP

• Trained in cGMP documentation practices, including SOP’s, Data Forms, and proper lab notebook keeping

RESEARCH TECHNOLOGIST Spherics Inc. Mansfield, MA (12/2005-1/2006)

• cGMP Clean Room: Encapsulated FDA approved drugs coated with proprietary Bioadhesive formulation in preparation for clinical trials

• Assisted technicians in coating of capsules and drug pellets and in operation of Mixer, Extruder and Spheronizer assemblies to make drug pellets

• Knowledge of Gowning Procedure for cGMP. Documented and Verified Data and Procedures

• Performed Swab Testing on machine parts for trace contamination analysis

• Assisted in R&D: Ground Bioadhesive polymer for preparation of polymer to coat drugs.

o Determined moisture content of pellets using heated moisture analyzer

o Familiar with operation of Dissolution Apparatus with on-line UV-Vis for drug concentration studies

• Researched Chemical and Hazardous Waste Storage information for new solvent bunker which expedited approval of bunker by town fire department

Prior Employment History

TEXTILE TECHNICIAN, Merchandise Testing Laboratories Brockton, 5/1991-8/1993

ENVIRONMENTAL TECHNICIAN, Battelle Ocean Sciences Duxbury, MA 4/1990-8/1990

LABORATORY TECHNICIAN, Oliveira Environmental Testing, Bridgewater, MA 5/1989-4/1990

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