Guang-Chen (Eric) Fang
Dept of Genetics and Biochemistry
Rm 300, Biosystems Research Complex
Clemson University
Clemson, SC 29634-5277
Work: 864-***-****
Mobile: 864-***-****
Evening Phone: 864-***-****
Email: *****@*******.***
Country of citizenship: United States of America
Veterans' Preference: No
Contact Current Employer: Yes
AVAILABILITY Job Type: Permanent
Work Schedule: Full Time
Desired Work Environment Post-graduate
New Professional
Mid-Career Professional
WORK EXPERIENCE Clemson University 8/2008 - Present
Clemson, SC US
Hours per week: 40
Postdoc Research Associate
(A) Plant genomics research on (a) chestnut: physical mapping of chestnut genome, using comparative genomics approach to identification of blight resistant QTLs and further development of blight resistant transgenic American chestnut for chestnut reforestation, construct chestnut genome resource as a model for woody plant genome studies (Achievement: a ms under preparation), (b) Aquilegia, an ecological model plant: characterization of genome structure and components associated with environment adaptation, use Aquilegia genome as a model system to understand the genome evolution from monocots to dicots (Achievement: a ms accepted by BMC genomics), (c) Mimulus, an environmental model plant: characterize the genome components for species radiations and environmental adaptation (Achievement: a ms under preparation).
(B) Establishment of a high throughput genome mapping pipeline (Achievement: hundreds of markers can be mapped to genome in 2-3 weeks).
(Contact Supervisor: Yes, Supervisor's Name: Dr. Albert Abbott (Clemson Endowed Chair Robert an, Supervisor's Phone: 864-***-**** )
Clemson University, Dept of Entomology, Soil Science and Plant Pathology 9/2006 - 7/2008
Clemson, SC US
Hours per week: 40
Postdoc Research Associate
(A) Understand the molecular mechanisms underlying the broad-spectrum biocontrol activity of Pseudomonas synxantha BG33R: use biochemistry, molecular genetic and genomics approaches to (a) purify and characterize compounds responsible for the biocontrol activity and (b) identify genes involved in the biosynthesis, secretion and regulation of the biocontrol factors (Achievement: a ms prepared for submission).
(B) Biocontrol of the Peach Tree Short Life Syndrome (PTSL) by a rhizospheric bacterium Pseudomonas synxantha BG33R.
(Contact Supervisor: Yes, Supervisor's Name: Dr. Daniel A. Kluepfel (Research Leader. USDA, ARS, Supervisor's Phone: 530-***-****)
Clemson University Genomics Institute 11/1999 - 8/2006
Clemson, SC US
Hours per week: 40
Postdoc Research Associate
(A) BAC library construction (Achievement: constructed more than 20 BAC libraries from a variety of organisms, ranging from microorganisms to plants and animals, and distributed to researchers worldwide for genome characterization and gene isolation)
(B) Comparative genomics of the Hox gene clusters in Hemichordates (acorn worm) and Bivalves (oysters) (Achievement: identified Hox clusters from the less-studied phylogenetic clades).
Clemson University, Dept of Plant Pathology and Physiology 5/1996 - 10/1999
Clemson, SC US
Hours per week: 40
Postdoc Research Associate
Signal transduction for pathogenesis of plant pathogenic fungi: Using molecular genetics approaches, such as gene cloning, Southern, Northern, PCR, site-directed mutagenesis and biochemistry analyses to study signal transduction of fungal infection process (Achievement: a ms published). (Contact Supervisor: Yes, Supervisor's Name: Dr. Ralph A. Dean (William Neal Reynolds Distingui, Supervisor's Phone: 919-***-**** )
Purdue University 8/1990 - 5/1996
West Lafayette, IN US
Hours per week: 40
Graduate Research Associate
(A) Molecular genetics of fungal differentiation: Characterization of the genes highly expressed during sporulation of Colletotrichum graminicola. The study involved cDNA library construction, screening, sequencing, gene disruption and physiological and biochemical analyses to understand the functional roles of the genes.
(B) Molecular genetics of plant-microbial interactions: used Colletotrichum/Corn system to study genes activated during disease development. The study involved using different maize cultivars and fungal strains to address the roles of candidate genes during the plant-microbial interactions.
Academia Sinica 5/1988 - 7/1990
Taipei, Taiwan Taiwan
Hours per week: 40
Research Associate
(A) Protein purification and characterization from rice leaves: The study involved using size filtration, ion exchange, affinity chromatography and FPLC to isolate and purify amylase from rice leaves and generate antibody from the purified compound for immunological study of the protein in different tissues of rice plant.
(B) Characterization of the maize P locus: RFLP mapping and sequencing the P locus from corn.
Academia Sinica 1/1984 - 9/1984
Taipei, Taiwan Taiwan
Hours per week: 40
Research Associate
Taxonomy and characterization of different isolates of Exserohilum turcicum: The study involved disease survey and collect fugal isolates from the field, purify and identify the isolates, and make fungal stocks for long-term storage.
EDUCATION Purdue University
W. Lafayette, IN US
Doctorate - 5/1996
30 Semester Hours
Major: Plant Pathology
Minor: Molecular biology
GPA: 3.1 out of 3.5
Relevant Coursework, Licensures and Certifications:
• Molecular determination plant diseases
• Plant disease epidemiology and management
• Seminar in Plant pathology
• Eukaryotic microbiology
• Physiology of plant diseases
• Plant virology
• Regulation of gene expression in eukaryotes
• Diagnosis plant diseases
• Seminar in microbiology and plant biology
• General biochemistry
• Nucleic acids
National Taiwan University
Taipei, Taiwan Taiwan
Master's Degree - 6/1986
33 Semester Hours
Major: Plant Pathology and Entomology
Minor: Microbiology
GPA: 4.0 out of 4.0
Relevant Coursework, Licensures and Certifications:
• Microbial physiology
• Radiotracer techniques in agricultural research
• Growth and differentiation
• Special topics on plant pathology
• Crop physiology
• Plant pathophysiology
• Crop tissue cultures
• Crop tissue culture lab.
• Applied mycology
• Applied mycology lab
National Taiwan University
Taipei, Taiwan Taiwan
Bachelor's Degree - 6/1983
Major: Plant Pathology and Entomology
Minor: Microbiology
Relevant Coursework, Licensures and Certifications:
• Calculus (6)
• General Physics (6)
• Physical Chemistry (2)
• General Chemistry and Lab. (4)
• Organic Chemistry and Lab. (4)
• Biochemistry (4)
• Biochemistry Lab. (2)
• Genetics (6)
• Statistics (6)
• Microbiology (3)
• General Botany and Lab. (4)
• Plant Physiology and Lab. (4)
• Methods in Microbiology and Lab. (3)
• Methods in Phytopathology and Lab.(A) (3)
• Plant Pathology and Lab. (4)
• Plant Disease Control (3)
• Applied Microbiology (3)
• Mycology and Lab. (3)
• Phytopathological Nematology and Lab. (3)
• Bacteriology and Lab. (3)
• Plant Virology and Lab. (3)
• Noninfectious Plant Diseases (2)
• Plant Diseases and Diagnosis (3)
• Agricultural Entomology and Lab. (B)
LANGUAGES Chinese
Spoken: Advanced
Written: Advanced
Read: Advanced
AFFILIATIONS American Association for the Advancement of Science, Washington, DC General member
American Phytopathological Society, St. Paul, MN General member
American Society for Microbiology South Carolina Branch General member
PROFESSIONAL PUBLICATIONS SELECTED PUBLICATIONS (after 2000)
Fang, G.C., Blackmon, B.P., David C. Henry, D. C., Staton, M.E., Christopher A. Saski, C.A., Hodges, S.A., Tomkins, J.P., Luo, H. 2010. Genomic tools development for Aquilegia: Construction of a BAC-based physical map. BMC Genomics 11:621.
Fang,G.C. Virginia Waldrop, Yonnie Wu, Chun-Huai Cheng, W. Patrick Wechter, Melissa B. Riley, and Daniel.A. Kluepfel, Broad-spectrum biological control activity of the rhizobacterium Pseudomonas synxantha BG33R (Manuscript in preparation for Molecular Plant Pathology)
Fang, G.C., Blackmon, B., Henry, D., Saski, C., Tomkins, J., and Albert, B. Development of chestnut genomics tools: physical mapping of the chestnut genome. (Manuscript in preparation for BMC Genomics)
Blenda, A., Fang, G.C., Saski, C., Munos-Torres, M., Henry, D., Vision, T., Willis, J., and Tomkins, J. A BAC-Based comparative physical framework resource for ecological and environmental genomics using the Mimulus spp. plant model. Manuscript in preparation.
Liang, H., Fang G.C., et al., 2007. Development of a BAC library resource for yellow poplar (Liriodendron tulipifera) and the identification of genomic regions associated with flower development and lignin biosynthesis. Tree Genetics and Genomes 3:215-225.
Ammiraju, J.S, Luo, M., et al., 2006. The Oryza bacterial artificial chromosome library resource: Construction and analysis of 12 deep-coverage large-insert BAC libraries that represent the 10 genome types of the genus Oryza. Genome Res. 16(1):140-147.
Cunningham, C., Hikima, J.I., et al., 2006. New resources for marine genomics: bacterial artificial chromosome libraries for the Eastern and Pacific oysters (Crassostrea virginica and C. gigas). Marine Biotechnology 8:521-533.
Chen, M., Presting, G., et al., 2002. An integrated physical and genetic map of the rice genome. The Plant Cell 14: 537-545.
Fang, G.C., Hanau, R.M., and Vaillancourt, L.J. 2002. The SOD2 gene, encoding a manganese-type superoxide dismutase, is up-regulated during conidiogenesis in the plant- pathogenic fungus Colletotrichum graminicola. Fungal Genetics and Biology 36:155-165.
Tomkins, J.P., Luo, M., Fang, G.C., Main, D., Goicoechea, J.L., Atkins, M., Frisch, D.A., Page, R.E., Guzman-Novoa, E., Yu, Y., Hunt, G., Wing, R.A. 2002. New genomic resources for the honey bee (Apis mellifera L.): development of a deep-coverage BAC library and a preliminary STC database. Genet Mol. Res. 1(4):306-16.
Payungsak Rauyaree, Choi, W., Fang, E., Blackmon, B., and Dean R.A. 2001. Isolation and characterization of genes expressed during early stages of rice infection with the rice blast fungus Magnaporthe grisea. Molecular Plant Pathology 2:347-354.
Fang, E.G., and Dean, R.A. 2000. Site-directed mutagenesis of the magB gene affects growth and development in Magnaporthe grisea. Molecular Plant-microbial Interactions 13:1214-1227.
ABSTRACTS OF MEETING PRESENTATIONS
Fang,E., Blackmon,B. et al., Physical Mapping Of Chestnut Genome: A Genome Resource For Fagaceae And Other Tree Species. Plant & Animal Genomes XVIII Conference. San Diego, CA. January 9-13, 2010.
Fang, G.C., Blackmon, B., et al., Physical mapping of Chestnut genome: A genome resource of Fagaceae and other tree species. Fagaceae Genome Meeting. Raleigh, NC. Nov. 11-14, 2009.
Fang, G,C., Waldrop, G.V., et al., Involvement of a sensor kinase gene (skrp 1122) for biocontrol activity by Pseudomonas synxantha BG33R. APS Centennial Meeting. Minneapolis, MN. July 26-30, 2008.
Fang, G.C., et al., 2007. A broad-spectrum antagonistic activity of the biocontrol agent Pseudomonas synxantha BG33R. APS.Son Joint Meeting. San Diego, CA. July 28 – August 1, 2007.
Blenda, A., Willis, J., Vision, T., Fang, G.C., Blackmon, B., Troutman, J., Henry, D., Ficklin, S., Atkins, M., Tomkins, J. 2007. HICF-Based physical mapping of Mimulus guttatus and M. Lewisii. Plant & Animal Genomes XV Conference (PAG), 2007. San Diego, CA, USA.
Blenda, A., Willis, J., Vision, T., Fang, G.C., Blackmon, B., Wiles, L., Troutman, J., Henry, D., Ficklin, S., Tomkins, J. 2006. Construction of an integrated physical-genetic map in Mimulus, a model plant system for ecology and evolution. Plant & Animal Genomes XIV Conference (PAG), 2006. San Diego, CA, USA.
Fang, G.C. 2005. More than just bacteria: Use microorganisms to study signal sensing and genomics of other species. SC-American Microbial Society 2005 Spring Meeting. Columbia, SC. April 1, 2005
Fang, G. C. et al., 2004. A BAC & EST library resource center for plant, animal, and microbial genomics. Plant & Animal Genome XII Conference. San Diego, CA.
January 9-14, 2004.
Fang, E. G. C., Presting, G., et al., 2001. Physical mapping of the rice genome. Plant & Animal Genome IX Conference. San Diego, CA. January 13-17, 2001.
REFERENCES Dr. Daniel A. Kluepfel USDA, ARS, CPGRU Research Leader
Phone Number: 530-***-****
Email Address: **********@*******.***
Reference Type: Professional
Dr. Hong Luo Clemson University Associate Professor, Graduate Coordinator, Department of Genetics and Biochemistry
Phone Number: 864-***-****
Email Address: ****@*******.***
Reference Type: Professional
Dr. Albert Abbott Clemson University Clemson Endowed Chair Robert and Lois Coker Trustees Chair in Molecular Genetics
Phone Number: 864-***-****
Email Address: *******@*******.***
Reference Type: Professional
Dr. Ralph A. Dean NC State University William Neal Reynolds Distinguished Professor, Department of Plant Path; Director of the Center for Integrated Fungal Research, NC State University
Phone Number: 919-***-****
Email Address: **********@****.***
Reference Type: Professional
Dr. Lisa J. Vaillancourt University of Kentucky Director of Graduate Studies
Phone Number: 859-***-****
Email Address: *******@***.***
Reference Type: Professional