Scientist / Manager Scientist

KRISTINE ANSENBERGER FRICANO

EDUCATION

Ph.D. 2010

University of Illinois at Chicago, College of Medicine

Department of Physiology and Biophysics

Advisor: Dale Buchanan Hales, Ph.D.

Thesis title: The Laying Hen and Flaxseed: a model for Dietary Intervention of Human Ovarian Cancer

B.S. 2005

Animal Sciences with Honors

University of Illinois at Urbana-Champaign

CURRENT POSITON

Postdoctoral Fellow

University of Illinois at Chicago, College of Medicine

Department of Pharmacology

Section of Cardiology

Advisor: Dr. Marcelo G. Bonini

Project: The role of Manganese Superoxide Dismutase in early stage cancer angiogenesis and late stage cancer survival.

PUBLICATIONS

Journal Articles

1) Ansenberger-Fricano, K., Chatterjee, S., Dallas, S., Green, P., Santos, J.H., Mason, R.P., Stadler, K., and Bonini, M.G. MnSOD (SOD-2) peroxidase activity: a determinant of cancer cell metabolic adaption and survival. Under Review Free Radical Biology and Medicine. June 2012.

2) Mao, M., Varadarajan, S., Ansenberger-Fricano, K., Fernandes, D.C., Tanaka, L.Y, Laurindo, F.M., Fukai, T., Mason, R.P., Vasquez-Vivar, J., Minshall, R.D. Stadler, K., Bonini, M.G. Nitroglycerin drives endothelial nitric oxide synthase activation via phosphatydylinositol 3-kinase (PI3K)/Protein kinase B (Akt) pathway. Free Radical Biology and Medicine. 2011 October 3.

3) Ansenberger, K., Richards, C., Zhuge, Y., Barua, A., Bahr, J.M., Luborsky, J.L., and Hales, D.B. Decreased severity of ovarian cancer and increased survival in hens fed a flaxseed-enriched diet for 1 year. Gynecol Oncol. 2010 Feb 12.

4) Ansenberger, K., Zhuge, Y., Mahon, C., Lagman, JA., Bahr, JM, Hales, D.B. “E-cadherin Expression in Ovarian Cancer in the Laying Hen, Gallus Domesticus, compared to Human Ovarian Cancer”. Gynecol Oncol. 2009 Jun;113(3):362-9.

5) Zhuge, Y., Ansenberger, K., Mahon, C., Lagman, J.A., Bahr, J.M., and Hales, D.B. “Cyp1B1 Expression in Ovarian Cancer in the Laying Hen Gallus Domesticus.” Gynecol Oncol. 2009 Jan;112(1):171-8.

6) Hales, D.B., Zhuge, Y., Lagman, J.A., Ansenberger, K., Mahon, C., Barua, A., Luborsky, J., and Bahr, J.M. “Cyclooxygenase Expression and Distribution in the Normal Ovary and Their Role in Ovarian Cancer in Gallus Domesticus”. Endocrine. 2008 Jun;33(3):235-44.

Abstracts

1) Ansenberger-Fricano, K., Summers, F., Dallas, S., Mao, M., Mason, R.P., Stadler, K., Santos, J.H., Bonini, M.G. “Manganese Superoxide Dismutase overexpression leads to cancer cell survival” presented at the Society for Free Radical Biology and Medicine Annual Conference. Atlanta, GA, 2011.

2) K Ansenberger; Y Zhuge; J Lagman; C Richards; A Barua; J Bahr; D Hales. “The Laying Hen and Flaxseed: a model of Human Ovarian Cancer” presented at the Annual Meeting of Society for the Study of Reproduction. Milwaukee, WI, 2010.

3) K Ansenberger; Y Zhuge; J Lagman; C Richards; A Barua; J Bahr; D Hales “E-cadherin Expression in Ovarian Cancer in the Laying Hen, Gallus Domesticus, compared to Human Ovarian Cancer” presented at the Keystone Symposium on Extrinsic Control of Tumor Genesis and Progression, Vancouver, British Columbia, 2009.

4) Hales, DB, Zhuge, Y. Ansenberger, K., Lagman, J.A., Mahon, C., Bahr, J.M., “Increased E-Cadherin Expression is a Hallmark of Epithelial Ovarian Cancer in the Laying Hen Gallus Domesticus” presented at the Endocrine Society Annual Meeting, San Francisco, CA, 2008.

5) Zhuge, Y. Ansenberger, K., Lagman, JA, Mahon, C., Bahr, J, Hales, DB. “Cyp1B1 Expression in Ovarian Cancer in the Laying Hen, Gallus Domesticus” presented at the Endocrine Society Annual Meeting, San Francisco, CA, 2008.

6) Ansenberger, K., Zhuge, Y., Mahon, C., Barua, A., Luborsky, J., Bahr, J. Hales, D.B. “Flaxseed/Omega-3 Fatty Acid Dietary Intervention in Ovarian Cancer in the Laying Hen, Gallus Domesticus” presented at the Annual Meeting of the Society for the Study of Reproduction, Kona, HI, 2008.

7) K. Ansenberger, Y Zhuge, JA Lagman, C Mahon, J Bahr, DB Hales “Epithelial lineage of ovarian carcinoma of the Laying Hen Gallus Domesticus” presented at the Reproductive Biology Biennial Meeting, University of Illinois, Allerton Park, IL, 2007.

8) K. Ansenberger, Y Zhuge, JA Lagman, C Mahon, J Bahr, DB Hales “Epithelial lineage of ovarian carcinoma of the Laying Hen Gallus Domesticus” presented at the Annual Meeting of the Society for the Study of Reproduction, San Antonio, TX, 2007.

9) Y Zhuge, JA Lagman, K Ansenberger, C. Mahon, J. Bahr, D.B. Hales “Molecular Characterization Spontaneous Ovarian Cancer In The Laying Hen Gallus Domesticus” Presented at Keystone Symposium on Inflammation and Cancer, Santa Fe, NM, Feb 2007.

GRANT ACTIVITIES

2010-Ongoing NIH Training Grant T32 HL072742-08

2007-2009 NIH Training Grant T32 HL007692

PROFESSIONAL SOCIETY MEMBERSHIPS

2011 Society for Free Radical Biology and Medicine

2006-2010 Society for the Study of Reproduction

2006-2010 Endocrine Society

2007-2010 Poultry Science Association

POSITIONS

2007-2010 Poultry Science Student Representative for the University of Illinois at Chicago

2007-2009 Graduate Student Council Representative

HONORS AND AWARDS

2007 Graduate College Travel Award (UIC)

2007 Graduate Student Council Travel Award (UIC)

2008 Larry Ewing Memorial Trainee Travel Award (SSR)

2008 Graduate Student Council Travel Award (UIC)

2008 Mark R. Lambrecht Award (UIC)

2009 Graduate College Travel Award (UIC)

2009 Graduate Student Council Travel Award (UIC)

REFERENCES

Marcelo G. Bonini, Ph.D.

Assistant-Professor

Section of Cardiology

Department of Pharmacology

University of Illinois at Chicago

1131 College of Medicine Research Building

909 S. Wolcott Ave.

Chicago, IL 60612

Office: 312-***-****

*******@***.***

Dale Buck Hales, Ph.D.

Professor and Chair

Department of Physiology

Southern Illinois University Carbondale

School of Medicine

Life Science II, Room 245

1125 Lincoln Drive

Carbondale, IL 62901

Office: 618-***-****

******@******.***

Joanna E. Burdette, Ph.D.

Assistant Professor

Department of Medicinal Chemistry and Pharmacognosy

University of Illinois at Chicago

College of Pharmacy

900 S. Ashland Avenue

Chicago IL 60607

Office: 3202 MBRB

Office: 312-***-****

*******@***.***

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