Manager Quality Control

SHEKETTA A. BROWN

*** **** ** *** *** • Meridian, MS 39305

Cell: 404-***-**** • ************@*****.***

QUALIFICATIONS SUMMARY

Research Medical Scientist with a strong business acumen and knowledge of whole animal system pharmacology, mid-level experience in analytical testing laboratories as well experience establishing an academic biomedical laboratory. Superb problem-solving, communication and organizational skills; work well independently as well as collaboratively with colleagues to promote a team environment.

Graduate medical education in the clinical research & drug development with applied pharmacology skills.

Laboratory expertise & analytical instrumentation: Tandem mass spectrometry (LC-MS/MS), Agilent HPLC, Shimadzu GC-FID, Thermo Nicolet Avatar FTIR, Atomic Absorption, UV/Vis Spectrophotometer, RT-PCR, Raw material analysis using Thin Layer Chromatography

Computer Software applications: Xcalibur, Bioworks 3.2, Seaquest database, EZChrom Elite, GC Solutions, Omnic, MS Word, Excel, Powerpoint

EDUCATION

MICHIGAN STATE UNIVERSITY, East Lansing, MI

Professional Science Masters, Integrative Pharmacology 5/2012-expected graduation

THE UNIVERSITY OF SOUTHERN MISSISSIPPI, Hattiesburg, MS

Bachelor of Science, Biological Sciences • Minor in Chemistry 2003

PROFESSIONAL EXPERIENCE

Pharma Pac LLC, DeKalb, MS

Raw Materials Department Manager 2010-2011

• Manage the assessment and processing of raw materials

• Comply with US Pharmacopoeia guidelines, SOP, and FDA

• CAPA investigation with out of specification raw materials

Validation Chemist 2009-2010

• Investigate any validations parameters that were not within specification

• QA/QC representative for GLP studies using GC-FID, FTIR, & wet chemistry

• Draft, review, sign and release validation protocols and reports

• Assist raw materials in processing & analyzing incoming samples as per USP methods

• Prepare notice of events/deviation reports for GC studies and take corrective action

Stability Chemist 2009

• QC chemist duties related but not limited to extractions, titrations, & colorimetric assays

• Follow SOPs and adhere to FDA compliance policies

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• Quantitative and qualitative analysis using HPLC, GC and UV/VIS

• Properly document assays in laboratory notebook and prepare release report for samples

Greenwood Leflore Hospital, Greenwood, MS 2007-2008

Pharmacy Technician

• Under the supervision of a pharmacist mix intravenous medication orders

• Troubleshoot & Stock Omnicell machines with floor medications throughout the hospital

• Assist employees and outpatients with prescription fills and refills

University of Mississippi, University, MS 2006

Summer Intern-Pharmacology Dept.

• In vivo toxicity testing of methamphetamine administration intraperitoneally in Swiss

Webster mice for behavioral analysis of the drug’s toxicity

• Prepare presentations for scientific conferences

• Perform RNA extractions for cDNA reverse transcription preparation

• Process cDNA transcription samples for RT-PCR gene amplification

• Worked cohesively with team to research the MMP9 gene role in methamphetamine drug

addiction

Tougaloo College, Tougaloo, MS 2005

Research Associate-Protein Chemistry

• Supervise and monitor the daily activities of student researchers to ensure production and

quality standards are met

• Independently ensure the routine performance of quality control tests to maintain effective

calibration and instrument operation

• Serves as a liaison for technical personnel in the resolution of problems and assist the

principal investigator in the management of the laboratory’s fiscal budget

• Document and upkeep lab records as well as maintain study documentation

• Analyze proteins and peptides using Electrospray Ionization (ESI) and nanospray (nanoESI)

• Microbiological sterile techniques with in vitro cell and tissue cultures

• SDS-page electrophoresis and trypsin digestion

Wells Fargo Financial, Grenada, MS 2003- 2005

Credit Manager

• Management Trainee program

• Advise customers on ways to effectively pay off creditors in a timely manner

• Execute loan application processes for real-estate, auto and personal loans

• Insurance loan compliance specialist

Bonner Analytical Testing Company, Hattiesburg, MS 2001

Chemistry Analyst

• Develop/Validate methodologies for various chemical metals and components in compliance

with Standard Operating Procedures (SOP) and regulatory guidelines

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• Implement experimental protocols and procedures

• Initiatively maintain, set up & conduct routine maintenance on analytical instrumentation

• Prepare reagents and maintain laboratory equipment and supplies

• Inform department supervisor of protocol and methodology issues that affected reliability of

data-assist with corrective action

PUBLICATION

Liu Y.; Brown, S.; Shaikh, J.; Fishback, J.A.; Matsumoto, R. R. Relationship between methamphetamine exposure and matrix metalloproteinase 9 expression. Neuroreport. 19(14)17 1407-1409, 2008.

ABSTRACT

Hennington, B.S., Kyle, P., Brown, S. Mapping Phosphorylation Sites of

Peptides Using Electrospray Ionization Mass Spectrometry. SERYM Conference.

Hattiesburg, MS. 2006.

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