Project Medical
Resume:
CURRICULUM VITAE
URMILA JAGADESHWARAN Email: ******@***.***
School of Biological Sciences, ***********@*****.***
Washington State University, Phone (Mob): 509-***-****
Pullman 99164-4236
Washington, USA
1. PERSONAL PROFILE:
Address for communication: 1650 NE Valley Rd, G5
Pullman, WA 99163
Language Proficiency: English, Malayalam, Kannada, Tamil, Hindi (all excellent), French (Basic)
2. EDUCATIONAL QUALIFICATIONS:
2006: PhD (Zoology), from University of Mysore, Karnataka, India. Title of the thesis: Ecology, isoenzymes and control studies on two dengue fever vectors
1997: Master of Science (Zoology) from University of Mysore, Karnataka, India.
1995: Bachelor of Science (Biochemistry, Botany, Zoology) from University of
Mysore, Karnataka, India.
3. POSITIONS HELD:
1. Post Doctoral Scientist (Sep 2007-till date) in the group of Prof (Dr.) David. F. Moffett, School of biological Sciences, Washington state University, Pullman, WA: in An NIH funded research project on ion transport and gut physiology of Mosquitoes.
2. Senior Research Fellow (2002-2005) in my own research project funded by Council of Scientific and Industrial Research (CSIR), India, on genetics of insecticide resistance.
3. Project Assistant (1998-1999) in a research project entitled Evaluation of insecticide resistance in Anopheles and Aedes mosquitoes.
4. RESEARCH EXPERIENCE:
In the last four years, my research analyzes mechanisms of the transport of nutrients and acid-base equivalents across the cell membranes. Our interests are centered on the physiology of epithelial cells, the cells that line surfaces of the body and are the key transporting cells of organs like intestine. We study the ion channels and transport mechanisms that are involved in the different segments of the mosquito midgut. A combination of electrophysiology, pharmacology, immunohistochemistry and molecular biology techniques are used to understand the different mechanisms. I studied the development and mechanisms of pyrethroid resistance for my doctoral studies.
5. EXPERIMENTAL SKILLS
1. Epithelial electrophysiology
2. Intracellular electrophysiology.
3. Theoretical understanding of the Voltage and patch clamp techniques.
4. Gel Electrophoresis (both polyacrylamide and agarose gel electrophoresis for the study of enzymes, proteins and DNA).
5. DNA/RNA isolation and estimation.
6. RT-PCR, q PCR, primer design, and Western blot.
7. Toxicology and xenobiotics of pyrethroids.
8. Spectrophotometric estimations of proteins and enzymes.
9. Histological techniques like fixing, staining, embedding and sectioning of tissues (microtomy).
10. Experienced in handling mice.
11. MS-word, Excel, PowerPoint, Photoshop, Corel draw.
12. Experienced with statistical packages like SPSS, Probit regression analysis.
6. TEACHING EXPERIENCE
1. Worked as a Lecturer for Postgraduate students (08/2005-04/2006) at Department of Zoology, University of Mysore. Karnataka, India.
2. Worked as a Lecturer for undergraduate students (07/2005-08/2005) at the Regional Institute of Education in Zoology, University of Mysore. Karnataka, India.
7. AWARDS AND FELLOWSHIPS
1. Postdoctoral Fellowship, NIH, Washington state University, Pullman, WA
2. Senior Research Fellowship, Council of Scientific and Industrial Research
(CSIR), New Delhi, India, (2002 -2005)
3. Karnataka State Government student Scholarship [class VI to Class X], India.
8. PUBLICATIONS
Signaling by intracellular H+ and Ca++ in larval Mosquito (Aedes aegypti) midgut epithelium in response to serosal serotonin. Moffett D. F., Urmila J, Onken H and Goss G. G. J.Insect Physio. J Insect Physiol. 2011 Dec 7 (In Press).
Cellular mechanisms of acid secretion in the posterior midgut of the larval mosquito (Aedes aegypti). Urmila, J., Onken H., M. Hardy, S. B. Moffett and D. F. Moffett; J. Exp. Biol. (2010) 213 (2), 295-300.
Biochemical characterization of deltamethrin resistance in a laboratory-selected strain of Aedes aegypti. Urmila, J. & V. A. Vijayan; Parasitol Res (2009) 104:1431–1438.
Efficacy of piperonyl butoxide (PBO) as a synergist with deltamethrin on five species of mosquitoes at Mysore Vijayan. V.A., Sathish Kumar .B.Y., Ganesh. K.N., Urmila. J., Fakoorziba. M.R and Makkapati. A.K. (2007). J. Commun. Dis,39(3):159-63.
Pyrethroid susceptibility and enzyme activity in two malaria vectors, Anopheles stephensi (Liston) and Anopheles culicifacies (Giles), from Mysore, India. Ganesh K.N., Urmila J and Vijayan V.A. (2003) Indian Journal of Medical Research, 117: 30-38.
Role of esterases and monooxygenases in the deltamethrin resistance in Anopheles stephensi Giles (1908), at Mysore Ganesh K.N., Vijayan V.A., Urmila J., Gopalan N and Shri Prakash. (2002)., Indian Journal of Experimental Biology, 40: 583-588.
Deltamethrin tolerance and associated cross-resistance in Aedes aegypti from Mysore. Urmila J., Vijayan V.A., Ganesh K.N., Gopalan N and Shri Prakash. (2001) Indian Journal Medical Research, 113: 103-107
Cross-resistance in a deltamethrin selected strain of Aedes aegypti to permethrin and fenvalerate. Urmila. J., Ganesh. K.N., Vijayan. V.A., Gopalan, N. and Rao. K.M. (2000) Proceedings of the 5th International Symposium on ‘Vectors and vector borne diseases
Feeding capacity of Toxorhynchites, Urmila. J., Ganesh. K.N. and Vijayan. V.A. (2000)Insect Environment, 6: 116-117.
Increased mosquito breeding activity in the University Campus Mysore, manasagangotri, Karnataka, Urmila. J., Ganesh. K.N., Pushpalatha. N and Vijayan. V.A. (1999) J. Commun. Dis, 31:203-206.
9. SYMPOSIA & PRESENTATIONS
1. The Society for Experimental Biology meeting, Glasgow, England, 2011
2. The Society for Experimental Biology meeting, Glasgow, England, 2009
3. 6th Int. Symposium on Vectors and vector borne diseases at Orissa, India,
2002.
3. 8th All India conf Cytology and Genetics, Bangalore Univ, 2001.
4. Evolutionary Biology conference. Karnatak University, India. 2001.
5. 14th Int. Cong. Geographic Medicine and 15th Iranian Congress of Physiol.
Pharmacol. Shiraz University of Medical Sciences, Iran. 2001.
6. 5th Int. Symposium on ‘Vector and vector borne diseases’. Punjabi University,
India. 2000
7. Entomocongress, International. Conference on Perspectives for New
Millennium. Kerala University, India. 2000.
8. 13th National congress on. Parasitology, Bangalore University, India. 1999.
10. OTHER PROFESSIONAL EXPERIENCES
1. Member of American physiological society (APS)
2. Member of Society for Experimental Biology and medicine (SEBM)
3. Member of Entomological society of America (ESA)
4. Featured member of Biltmore who’s who
5. Member of American Institute of Biological Sciences (AIBS)
6. Member of Society of Vector ecology (SOVE)
7. Fellow of Royal Society of Tropical Medicine and Health (RSTMH)
8. Reviewed manuscripts
9. Life member of National Environmental Science Academy (NESA), New-Delhi.
10. Judging panel Member for the Science and Engineering Annual Undergraduate Research Poster Competition, WSU Pullman, WA 2009 and 2010
9. REFERENCES:
1. Dr. David. F. Moffett
Professor and Project investigator,
School of Biological Sciences
Washington State University
Pullman WA 99164 USA
Phone : 509-***-****
email : ********@***.***
http://sbs.wsu.edu/faculty/?faculty/23
3. Dr. Leonard. B. Kirschner
Emeritus Professor,
School of Biological Sciences
Washington State University
Pullman WA 99164 USA
Phone : 509-***-****
email : ******@***.***
2. Dr. Horst W. H. Onken
Associate Professor,
Department of Biological Sciences
Wagner College
One Campus Road
Staten Island, New York 10301 USA.
Phone : 718-***-****
email : *****.*****@******.***
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