MARK KENT

**** ****** ****** • Sunnyvale, California 94089

408-***-**** • l4m3iz@r.postjobfree.com

PROCESS CHEMIST; SENIOR RESEARCH ASSOCIATE

Biotech / Pharmaceutical Industry

Accomplished Chemist with extensive experience designing synthetic processes, optimizing existing processes, and improving efficiencies. Analytical capabilities with additional ability developing safe transfer methods. Effective trouble shooter capable of implementing manufacturing processes and controls. Skilled researcher with thorough experience handling, synthesizing, purifying, and characterizing complex organic molecules. Talented communicator able to convey science to a diverse audience. Additional areas of expertise:

Biotechnical, Pharmaceutical Chemistry Intermediates & Products • Multi-Step Organic Synthesis

Research to Production Lifecycle • Experimental Design, Execution & Optimization • Problem Solving

Analytical, Chromatography Techniques: NMR, IR, GC, HPLC, LCMS, Flash

PROFESSIONAL EXPERIENCE

MAKChem CONSULTING, Sunnyvale, CA • 2006- present

A source for advice on Process Development applicable to the biotech, pharmaceutical, and polymer industries.

Owner and Chemistry Consultant

Working knowledge of manufacturing processes, cGMP practices, and ICH and CFR guidelines. Writing of test methods, validation documentation, SOPs, HazOPs, MSDS, white papers and safety procedures.

A SCHMAHL SCIENCE WORKSHOP, San Jose, CA • 2008-2010, 2011-present

A science-based scholastic program developed to improve K-12 understanding of the life, physical, and earth sciences to both home-schooled and public school children.

Mentor on Science Fair Projects (part-time)

Assist middle school and high school students as they learn what is entailed by real-life research projects.

Middle & High School Chemistry Teacher (part-time)

Teach science curriculum to students. Plan and execute curriculum with appropriate experiments. Deliver lectures. Supervise student activity in both labs and lectures. Demonstrate real-world applications of classroom science.

K-6 science teacher (part-time)

Present science-based hands-on workshops to students. Execute curriculum with age-appropriate experiments. Supervise student hands-on activity in labs. Discuss science as appropriate to levels of understanding.

Operational Highlights:

• Developed curriculum that enhanced understanding of and appreciation for chemistry among high school-aged students.

• Developed curriculum for an introductory chemistry class aimed at middle school students.

• Motivated and challenged students to achieve greater effort.

• Developed and executed plan for safe handling of chemicals within organization

• Developed and executed plan for safe handling of hazardous waste materials within organization

Cont’d…

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SYMYX CORPORATION, Santa Clara, CA • 2008

Assists companies with R&D integration, designs and builds systems to reduce R&D risks.

Contract Scientist

Designed experiments to examine catalysts used in biodiesel preparation. Analyzed individual reactions and performed data analysis.

Operational Highlights:

• Ran several hundred reactions that scrutinized solvent, catalyst and substrate effects on the overall reaction products.

• Designed and managed experiments within restrictive time parameters.

AIR LIQUIDE ELECTRONICS (ALOHA), Fremont, CA • 2006-2007

A global company producing high-purity organometallics used by fabrication companies to produce specialty chips.

Process Chemist

Devised safe methods to transfer high-purity organometallics between canisters without exposure to water or oxygen. Developed and wrote SOPs, HazOPs, and MSDS. Worked closely with the analytical group. Trained and managed 4 technicians.

Operational Highlights:

• Ensured timely shipping of materials by developing safe efficient methods for product transfer.

A.P. PHARMA INC., Redwood City, CA • 2005-2006

A small specialty pharmaceutical company developing medical treatments based on polymer-based drug delivery systems.

Senior Research Associate

Designed and executed experiments to study the effects on molecular weight and other physical properties of targeted polymers. Analyzed data and prepared reports.

Operational Highlights:

• Significantly reduced experiment backlog by preparing copious samples.

• Improved laboratory setting by implementing cleaning and order processes.

NANOSYN, Menlo Park, CA • 2005

A small company that prepares libraries of chemical compounds using combinatorial methods.

Contract Scientist

Employed combinatorial methods to prepare libraries of pharmaceutical intermediates. Delivered compounds to the analytical group. Interpreted results prior to shipping libraries to customers.

Operational Highlights:

• Synthesized and analyzed numerous libraries of compounds results.

• Completed tasks on a limited budget with highly restricted funding.

Cont’d…

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CYTOKINETICS, San Francisco, CA • 2004-2005

A small company that produces drugs for cardiovascular and oncology purposes.

Contract Scientist

Designed, executed and optimized a synthetic sequence for a drug currently in phase III clinical trials. Assayed results utilizing NMR, LCMS, and HPLC. Interpreted results.

TARGESOME, Palo Alto, CA • 2002-2003

A small company that was in the process of developing liposome materials for use in drug delivery systems.

Contract Scientist

Synthesized functionalized dextran for use in liposome materials. Implemented flexible practices to accommodate a change in company business plans and directions. Supervised three chemists and three technicians.

PREVIOUS CAREER HISTORY

AFFYMAX, Palo Alto, CA

Research Associate

• Successfully prepared small molecule and linker molecules within time parameters.

• Improved efficiencies by recommending process changes.

CATALYTICA, Mountain View, CA

Process Chemist

• Generated 20% higher overall yields in preparing new catalyst materials.

CLONTECH, Palo Alto, CA

Senior Research Associate

• Boosted company’s market position as a reagents supplier by developing and optimizing the multi-step synthetic sequence used to prepare 2 different families of DNA modification reagents.

PUBLICATIONS & PATENTS

Nelson, Paul S., and Kent, Mark A., U.S. Patent 5,451,463 – non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides; issued 9/19/95.

TECHNICAL SKILLS

Microsoft Office Suite • Isis • SciFinder

PROFESSIONAL MEMBERSHIPS

American Chemical Society – Chair, Santa Clara Valley Section - 2008

American Chemical Society – Alternate Councilor, Santa Clara Valley Section

American Association for the Advancement of Science

Bay Area Biotech Consultants Network

Cont’d…

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EDUCATION

Master of Science in Organic Chemistry

University of Arkansas, Fayetteville, AR

Bachelor of Science in Chemistry

California Polytechnic State University, San Luis Obispo, CA

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