High School Assistant

Lisha Xu

Local Address *** * ****** ** • Apt ** • Ithaca, NY 14850 Permanent Address 12 Golden Hill Ave • Shrewsbury, MA, 01545 Cell 508-***-**** • Home 508-***-**** ****@*******.***

Objective

To obtain a position in the area of biomedical research to gain experience and prepare for a career in the health care and pharmaceutical industry.

Education

• Cornell University, College of Human Ecology, Ithaca, NY 2009-Present

Expected B.S. (2013), Human Biology Health and Society

• Massachusetts Academy of Math & Science, Worcester, MA 2007-2009

High School Diploma (2009)

Member of National Honors Society, Massachusetts Academy of Math and Science President of Future Doctors of America, Massachusetts Academy of Math and Science

• Shrewsbury High School, Shrewsbury, MA 2005-2007

Working Experience

• Biogen Idec Incorporation, Cambridge, MA Summer Intern in Research & Development 2012 Developed an accurate and sensitive assay for cerebral spinal fluid drug level determination in preclinical and clinical research in the department of pharmacokinetics and pharmacology that are very useful for future applications. Work includes pre-clinical trial sample analysis, data interpretation, and report preparation

• UMASS Medical School, Worcester, MA Summer Intern in Neurobiology 2011 Developed disease mice model for Amyotrophic lateral sclerosis.

• Department of Human Development, Cornell, Ithaca, NY Research Assistant 2011 Participated in large quantities of data transcription of collected video and audio files for future data analy¬sis in children’s autobiographical memory project. Obtained experience with qualitative data collection and analytical method used in social sciences research.

• Massachusetts General Hospital, Boston, MA Summer Intern in Anesthesia and Critical Care 2010 Purified and reconsituted large quantities of human α1β3γ2 -aminobutyric acid type A (GABAA) receptors for identification of drug binding sites.

• Department of Plant Science, Cornell University, Ithaca, NY Research Assistant 2010 -2011 Identified and manipulated pathogens known to attack plants, such as the bacteria, fire blight, known to attack apple, pear and onions.

• Department Neurobiology UMASS Medical School, Worcester, MA Volunteer June 2009 -August 2009 Analyzed individual neurons from drosophila using twin-spot mosaic analysis to understand the origins of neurons and the mechanisms that control cell fate.

• Why Me and Sherry’s House, Worcester, MA Volunteer 2007-2009 Assisted with organization of important charity events, planned fundraising events, worked with individual children and families, and performed general office duties.

• Kumon Learning Center, Shrewsbury, MA Tutor 2004 -2009 Worked with different children from diverse backgrounds from pre-K to 12th grades to improve their math and reading abilities.

Publications

• The heterologous expression, purification and functional reconstitution of large quantities of human α1β3γ2 -aminobu-tyric acid type A (GABAA) receptors for identification of drug binding sites by photolabeling. Receptors, Signaling and Signal Transduction. Joint work with Dostalova Z. et al. Published on 2010

Technical Skills Biotechnology:

• Microbiology -Experience with aseptic techniques,reagents and media preparation, isolation of nutri¬tional mutants, stains and coverslip slides, counting cells, familiarity with E. coli

• Molecular Biology -Experience with with primer designing, PCR, DNA transformation, cell transfection

• Biotechnology -Experience with DNA and protein electrophoresis (Agarose Gel, SDS-PAGE), column chromatography, enzyme and hormone assays, purification and identification of plasmic DNA, DNA fingerprint, northern and western blot

• Cell Culture and Animal Model -Experience with maintenance of cells lines, freezing and thawing of cells, experience with animal models, maintenance and mating (Drosophila and mice), larva and CNS drosophila dissections, creating diseased mice model, genetic, tissue extraction, spinal cord dissection

Bioanalytical:

• Developing LC/MS/MS assays for the quantitation of drugs and their metabolites in biological matrices in support of drug discovery PK and PK/PD studies which includes sample analysis, data interpreta¬tion, and report preparation.

• Knowledge of various LC/MS machines (Shimadzu) and Analyst software, methods, and protocols

Computer:

• Familiar with Microsoft Word, Microsoft Excel, Microsoft Powerpoint, Photoshop, Microsoft Publisher

• Designed websites using html and CSS, familiarity with C++ and Dr.Scheme

Relevant Courses

Biological with Lab Chemistry with Lab Physics with Lab Calculus Statistics Biochemistry Organic Chemistry with Lab Nutritional Sciences Nutrition and Metabolism Global Health Adolescent Development Social Sciences and Nutrition

References

Furnished upon request

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