Synthesis of organic molecules and polymers

MANDAPATI KAVITHA

PRESENT ADDRESS PERMANENT ADDRESS

Research Assistant D/o M.Pulla Reddy

Materials Research lab Beerapally (Village),

Dept of Chemistry Kunchaparty (post)

National University of Singapore Vemsoor (mandal)

Singapore -117543. Khammam (dist)

Ph. 006*-********. Andhra Pradesh-507164

E-mail: ***********@*****.*** India, Ph.91-876*******

OBJECTIVE

As a hardworking researcher, I look forward to reach an eminence by optimally exploring my knowledge and skills to contribute efficiently towards the research and development activities in the area of Synthetic chemistry.

PERSONAL INFORMATION

Female, Married, Date of Birth: Aug 02nd 1982. Nationality: INDIAN, Singapore permanent residence.

RESEARCH EXPERIENCE

 Research assistant - Under the guidance of Assoc\Prof. Suresh Valiyaveettil, Department of Chemistry at National University of Singapore (NUS) (Singapore-117543) from May, 2008 to till date.

Project Title: “Synthesis of low band gap cross conjugated polymers - fused ring donor acceptor systems”.

 Worked with Aurobindo pharma limited (Andhra Pradesh, Hyderabad, India, http://www.Aurobindo.com/htmls/home.htm) as a Chemist in “Quality Control and Regulatory affairs department” from Feb 2007 to January 2008.

 Worked with Sai advantium pharma limited (Andhra Pradesh, Hyderabad, India) as a Jr.Research assistant in “Research and Development, Quality Control department” from January 2006 to February 2007.

• Projects handled:

• Citalopram hydrogen bromide.

• Gabapentin

 Worked with Hetero Drugs Limited (Andhra Pradesh, Hyderabad, India, http://www.heterodrugs.com/htmls/home.htm) as a Trainee in “Research and Development, IPM department” from June 2004 to January 2006.

EDUCATIONAL QUALIFICATIONS

M. Sc. (Organic Chemistry): 2002-2004 Osmania University, Hyderabad –500 007, Andhra Pradesh, India.

Bachelor of Science (Biochemistry): 1999 – 2002, Kakatiya University, Warangal, India.

Intermediate (B.Z.C) : 1997-1999 Board of Intermediate, Andhra Pradesh, India.

PUBLICATIONS

1. Ganapathy Balaji, Mandapati Kavitha, and Suresh Valiyaveettil, “Highly fluorescent low band gap thienoimidazole - conjugated homopolymers: Synthesis and photophysical properties”- (Manuscript under preparation).

2. Ganapathy Balaji, Mandapati Kavitha, Manoj parameswaran and Suresh Valiyaveettil, “Poly long alkylated thienoimidazole, a new low band gap polymer with electron donor-acceptor fragment for light emitting diodes and photovoltaic cells”- (Manuscript under preparation).

3. Ganapathy Balaji, Mandapati Kavitha, and Suresh Valiyaveettil, “Synthesis and structural characterization of Thienoimidazole oligomers”- (Manuscript under preparation).

WORK SKILLS

 To carry out synthesis, separation and characterization of organic compounds and

Polymers.

 Scale up of reactions to multi gram scale and their purification and isolation.

 Conversant with various organic syntheses techniques and handling of air sensitive

and light sensitive reagents.

 Conversant with purification techniques like flash chromatography, size exclusion chromatography, CombiFlash, Soxlet extraction, Precipitation, Recrystallization methods etc.

 Highly organized and has the habit of neatness in the lab and follow OSHE safety policies, GLP (Good laboratory practices), in the work place.

Hands-on experience in operating and analyzing instruments are:

 NMR (300MHz Bruker), FTIR (Shimadzu, Perkin Elmer), GPC (Waters), CombiFlash, UV/Vis (Shimadzu, Perkin Elmer) – Solution and solid state, Fluorescence spectrometer (Shimadzu), TGA,DSC(TA model),HPLC (Shimadzu), Polarimeter (SISCO), Dissolution apparatus, Atomic absorption spectroscopy, Auto titrator, Pharma test apparatus, Disintegration test apparatus, preparation of SOP’s for instruments.

 Preparation of MSDS, COA (Certificate of analysis), Specification and STP (Standard test procedures) for drug substances.

 Exposure on cGMP and ICH quality, ISO 9001-2000(QMS), USFDA, EDQM regulatory guidelines.

COMPUTER SKILLS

 Conversant with ISIS, Chemdraw, ACD software, Origin software, Scifinder for literature, Patent literature searching by using Dolphin,espacenet soft ware’s and orange book.

 Diploma in Computer Applications, expert in Excel, Word, PowerPoint, MS access.

REFERENCES

ASSOC. PROF. SURESH VALIYAVEETTIL

Research Supervisor

Department of Chemistry

National university of singapore

Singapore– 117543.

Phone: (65)- 6516 4327;

E-mail: *****@***.***.**

PROF. GO MEI LIN

Medicinal Chemistry laboratory

Department of Pharmacy

National University of Singapore.

Singapore-117543.

Phone: (65) 6516 2654;

E-mail: *******@***.***.**

DR. GEORGE GIA PASTRON

Department of pharmacy

National University of Singapore

Singapore – 117543,

Phone: (65)- 6516-1876

e-mail : *****@***.***.**

DR.BIPUL BARUAH

Principal scientist

Medicinal Chemistry laboratory

Saiadvantium pharma limited

Hyderabad, A.P-500050.

India.

Phone: (91-986*******;

Off: (91-402*******

E-mail: *****.*@************.***.

RESEARCH SUMMARY

“SYNTHESIS OF LOW BAND GAP CROSS CONJUGATED POLYMERS - FUSED RING DONOR ACCEPTOR SYSTEMS”.

The lightness of weight, processability, and corrosion resistance of conjugated organic polymers have been the drive to replace a number of metal applications and to produce novel materials. The design of zero-approaching band gap polymers is important in order to achieve intrinsic conductivity in these materials. In order to minimize the band gap, bond-length alternation (BLA) along the main chain has to be as small as possible. Minimization of the BLA can be achieved through two pathways: (i) fused ring systems and (ii) alternation of electron-donors and -acceptors in the main chain. Using the two strategies, 4,6-Di(2-thienyl)thieno[3,4-b]imidazole derivatives were synthesized and polymerized into soluble conjugated polymers with band gaps around 1.63-1.65 eV, which is between that of poly(5,7-Di(2-thienyl)thieno[3,4-b]benzene)andpoly(5,7-Di(2-thienyl)thieno[3,4-b]pyrazine). These polymers and oligomers were structurally characterized by NMR, FT-IR, GPC, Mass, HR-MS, elemental analysis. The electronic and optical properties were studied by solution and solid-state UV/Vis absorption, emission spectroscopy, and cyclic voltammetry. The effect of symmetry on the properties of the molecules and fabrication of the polymers into photovoltaic devices was studied as well.

Synthesized Some Polymers:

PROFESSIONAL SUMMARY:

 Having 4.5 years experience.

 Team work and dedication in work.

 Ability to absorb technical knowledge quickly.

DECLARATION

I hereby declare that the above-mentioned particulars are correct to the best of my Knowledge and belief.

(Kavitha.M)

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