Zhilian Zhou

Citizenship: USA

*** *** ******, **********, ******* E-Mail: imaaxl@r.postjobfree.com Phone: 919-***-****

Profile

Highly motivated scientist working on the technology development & materials design for polymer and coating materials. More than 10-year research and product development experience with strong commitment to excellence and results. Demonstrated excellent communication skills and strong project management capability.

Education

Ph. D. Chemistry (2006), University of North Carolina, Chapel Hill, NC

Dissertation title: New polymer electrolyte membranes for next generation fuel cells

Advisor: Professor Joseph M. DeSimone

M. S. Chemical Engineering (2003), University of Minnesota, Minneapolis, MN

Thesis title: Fluorinated, water soluble block copolymers

Advisors: Professors Timothy P. Lodge and Marc A. Hillmyer

M. S. Materials Science (1999), Tianjin University, Tianjin, China

Thesis title: Synthesis and characterization of polyketone

B. S. Polymer Materials (1996), Tianjin University, Tianjin, China

Core Skills

Technical Experience

Polymer Design and Synthesis, Polymer Coatings, Pilot Scale Manufacturing, Organic Synthesis, Nanoparticle Design and Fabrication, Optical Films, Fuel Cells, Photovoltaics

Project Management

Grant Strategy and Authorship, Project Planning and Execution, Operations and Strategic Planning

Material Characterization Methods

Size Exclusion Chromotography (SEC), Nuclear Magnetic Resonance (NMR), FTIR, Rheology, Instron, Dynamic Mechanical Thermal Analysis (DMTA), Differential Scanning Calorimetry (DSC), Thermogravimetry Analysis (TGA), Dynamic Light Scattering (DLS), Small Angle X-ray Scattering (SAXS), Scanning Electron Microscope (SEM), Optical Microscope, Transmission Electron Microscope (TEM), Atomic Force Microscopy (AFM) , Fluorescent and Confocal Microscopy

Professional Experience Highlights

Project Leader, Jan 2009-Present Liquidia Technologies, RTP, North Carolina

Principal Scientist, Oct 2007-Present

Scientist, Aug 2006 - Oct 2007

• Polymeric particles for consumer product applications

o Led a team engaged with Procter & Gamble (P&G) in developing polymeric particles for hair care and body wash;

o Executed workplan, managed budget and operations, communicated with P&G regularly on technical progress;

o Designed and developed polymeric particles of controlled size, shape, surface energy and modulus;

o Brought multiple formulations from lab scale to roll to roll pilot production;

• Nanoparticles for drug delivery

o Led a multi-discipline team engaged with Johnson & Johnson (J&J) in developing nanoparticles for delivery of biological APIs;

o Was responsible for project planning and execution, technical progress exchange, personnel and budget management;

o Developed polymeric and lipid based nanoparticle systems and achieved intracellular delivery of antibody scaffolds; controlled the fabrication process to achieve desired particle composition, physical and surface properties and release profile of the APIs

• Polymeric material design and process development

o Developed elastomeric fluoropolymers used as structured coatings on polyester substrates; optimized coating conditions for multiple formulations including thermoplastic polymers, UV curable resins, and various active pharmaceutical ingredients

o Prepared and improved production yield of polymeric particles using soft lithography approach; brought multiple projects from lab scale to pilot manufacturing; investigated rheological, thermal and mechanical properties of polymers to improve the material design and fabrication process;

• Patterned films for solar cells and optics

o Served as PI on a National Institute of Standards & Technology (NIST) sponsored multi-million project; Was responsible for budget management, workplan execution, data analysis, report preparation & communication with project sponsors

o Led a group of engineers, chemists and physicists to improve the efficiency of thin film photovoltaics through nano-patterning of conductive polymers and metal oxides, precisely control the coating process to achieve the desired structure;

o Developed multiple optical films (antireflective coatings, nanowire grid polarizer, etc) for display and clean energy applications; Worked with external partners to evaluate prototype devices;

Research Assistant, Chemistry Department, UNC-Chapel Hill, Chapel Hill, North Carolina, August 2003- July 2006

• Designed and synthesized highly fluorinated polymers for fuel cell applications

• Fabricated chemically crosslinked, high surface area proton exchange membranes; Characterized proton exchange membranes using TGA, DMTA, Instron, AC impedance, and fuel cell testing station

• Developed new fabrication methodologies for catalyst ink, composite membranes and membrane electrode assemblies

• This work was highlighted in Science and led to an issued patent

Research Assistant, Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota, September 2000- July 2003

• Synthesized novel, mono-disperse triblock copolymers composed of hydrophilic, hydrophobic and fluorinated blocks by anionic polymerization; Characterized molecular structure of polymers using SEC, NMR, IR

• Investigated thermal and mechanical properties of polymers using DSC and Rheology

• Studied micelle structures in solution and melt morphologies of block copolymers using DLS, SANS, SAXS, rheology and TEM

Research Assistant, School of Chemical Engineering, Tianjin University, China, September 1996- July 1999

• Synthesized and characterized polyketone

• Studied the binary noble metal catalyst system for polyketone polymerization

Honors:

• Liquidia award for technical and leadership achievement, Liquidia Technologies, 2011

Grants

• National Institute of Standards and Technology (NIST)- Advanced Technology Program (ATP): “High efficiency thin film photovoltaics through precision nanopatterning”, 2008, PI

Reports:

• “High efficiency thin film photovoltaics through precision nanopatterning”, quarterly reports, 2008.

Peer-Reviewed Publications

1. Zhilian Zhou, Zhibo Li, Yu Ren, Marc A. Hillmyer and Timothy P. Lodge, “Micellar shape change and internal segregation induced by chemical modification of a Tryptych block copolymer surfactant”, Journal of American Chemical Society (JACS), 125, 101**-*****, 2003. (115 citations)

2. Zhilian Zhou, Raymond N. Dominey, Jason P. Rolland, Benjamin W. Maynor, Ashish A. Pandya, and Joseph M. DeSimone, “Molded, high surface area polymer electrolyte membranes from cured liquid precursors”, Journal of American Chemical Society (JACS),, 128, 129**-*****, 2006 (33 citations)

3. Timothy P. Lodge, Marc A. Hillmyer, Zhilian Zhou and Yeshayahu Talmon, “Access to superstrong segregation regime with nonionic ABC block Copolymers”, Macromolecules, 37, 6680-6682, 2004 (48 citations)

4. Lei Zhang, Zhilian Zhou, Bin Cheng, Joseph M. DeSimone and Edward T. Samulski, “ Superhydrophobic behavior of a perfluoropolyether lotus-leaf-like topology”, Langmuir, 22, 8576-8580, 2006 (88 citations)

5. Zhilian Zhou, Ginger Rothrock, Doug Mar, Xianshen Meng, Jennie Orr and Robert Henn, “Low cost manufacturing of patterned films with nano-precision”, SID DIGEST, 534-536, 2008

6. Meredith J. Hampton, Stuart S. Williams, Zhilian Zhou, Janine Nunes, Doo-Hyun Ko, Joseph L. Templeton, Edward T. Samulski and Joseph M. DeSimone, “The patterning of sub-500nm inorganic oxide structures”, Advanced Materials, 20, 2667-2673, 2008

7. Stephanie E. A. Gratton, Stuart S. Williams, Mary E. Napier, Patrick D. Pohlhaus, Zhilian Zhou, Kenton B. Wiles, Benjamin W. Maynor, Clifton Shen, Tove Olafsen, Edward T. Samulski and Joseph M. DeSimone, “The pursuit of a scalable nanofabrication platform for use in material and life science applications”, Acc. Chem. Res., 41, 1685-1695, 2008

Patents

1. Zhilian Zhou, Xiansheng Meng, Joseph M. DeSimone, Benjamin W. Maynor, Jason P. Rolland, Kenton B. Wiles, “High fidelity, through hole film and associated method”, Applicaton number: 201********, 2011

2. Joseph M. DeSimone, Jennifer Y. Kelly, Jason P. Rolland, Zhilian Zhou, Ginger M. Denison, Raymond Dominey, “Liquid materials for use in electrochemical cells”, 200********, 2009

3. Joseph M DeSimone, Ginger D. Rothrock, Zhilian Zhou, Edward T. Samulski, Meredith Earl, Stuart Williams, “High fidelity nano-structures and arrays for photovoltaics and methods of making the same”, WO 2008/018936, 2008

4. Joseph M. DeSimone, Michael S Williams, Lauren Portnow, Colin Wood, Zhilian Zhou, Everett Baucom, Ginger D. Rothrock, “Use of acid derivatives of fluoropolymers for fouling-resistant surfaces”, WO 2007/025293, 2007

References:

1. Professor Joseph M. DeSimone

Department of Chemistry

University of North Carolina at Chapel Hill

Phone: 919-***-****

Email: imaaxl@r.postjobfree.com

2. Professor Edward T. Samulski

Department of Chemistry

University of North Carolina at Chapel Hill

Phone: 919-***-****

Email: imaaxl@r.postjobfree.com

3. Kyle Chenet

VP-Corporate Development

Liquidia Technologies

Phone: 919-***-****

Email: imaaxl@r.postjobfree.com

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