Manager Development

James A. Andrews, PhD, MS, Sr.

e-mail: **********@*****.***

**** ********** *****, *** *****, CA 92106

Phone: 619-***-****

"A grand and almost untrodden field of inquiry will be opened, on the causes and laws of variation" Charles Darwin

OBJECTIVE: A scientist, program manager, or director position in the biomedical field.

EXPERIENCE:

Principal Scientist Naval Health Research Center San Diego, CA

8/2008 - Present

• Vaccine efficacy for respiratory diseases

• Genetics of PTSD & TBI

• Evaluation of Biomarkers for PTSD, TBI

• Acting Department Head

• Authored grants & scientific reports

• PCR, qRT-PCR, & next generation sequencing for diagnostics of infectious disease

• Immunogenicity, serology, Luminex, & ELISA assay development/validation

• SAS, Prism, & R statistical packages

Grants/Contracts Manager Naval Health Research Center San Diego, CA

8/2008 - Present

• Awarded Federal grants and contracts

• Managed contract/grant proposal evaluation

• Contract/grant technical oversight

• Government report writing

• Program management of awards

• Used business development and expanded client portfolio

• Established the largest Research and development contract in the history of Navy medicine

• Blood clotting research

Scientific Consultant Lipid Sciences Pleasanton, CA

1/2006 - 9/2007

• Novel therapeutics and vaccines

• Clinical trial studies

• Assay development and validation

• Gas chromatography

• Artery plaque assessment

• Wetlab

Scientific Consultant MedStar Research Institute Washington, DC

1/2005 - 1/2007

• Genetic studies

• Platelet function and clotting

• Single nucleotide polymorphisms (SNPs)

• Clinical, swine, and rodent studies

• Cell culture

• Hematopoietic stem cell studies

• Stem cell injection and cardiovascular disease

Research Associate Covance Bioanalytical Chantilly, VA US

8/2001 – 2006

• Developed, validated, and ran assays

• ELISA, RIA, EIA, immunogenicity assays

• Immunogenicity studies

• Pharmacokinetic studies

• Contract studies for biotech and pharmaceutical clients

Scientist Cytimmune Sciences College Park, MD

9/2001 - 9/2002

• Formulations and pharmacology scientist

• Clinical trial lead

• Preclinical trials lead

• IND, GMP, GLP

EDUCATION:

PhD, Physiology and Biophysics Georgetown University SOM Washington, DC

2003-2008

• "Stress, Inflammation, and Atherosclerosis"

• Developed & validated pathogen assay

• Cell culture studies of monocytes, PBMCs, SMCs, and endothelial cells

• Molecular biology: microarrays, single nucleotide polymorphisms, qPCR, gels

• Wester Blots & immunohistochemistry

• Animal studies

• Clinical studies

MS, Neuroscience Youngstown State University Youngstown, OH

1997-2000

• Thesis: “Effects of Estrogen on the basolateral amygdala”

• Brain slices

• Electrophysiology/intracellular electrode recordings

• Pharmacology

BS, Biology Youngstown State University Youngstown, OH

1993-1997

• Thesis: “The Structure of Beta-aluminas using X-ray crystallography”

• Minor: Chemistry

NOTEWORTHY:

• High Honors

• Secret Clearance

• Lean Six Sigma Green Belt

• Wartime Veteran

PUBLICATIONS:

• Some authored reports are classified and not published in scientific journals.

• Andrews JA, Neises K. Peripheral Blood Mononuclear Cells and Posttraumatic Stress disorder; Peripheral Involvement in a Central Disease. Journal of Neurochemistry. November, 2011.

• Andrews J, Andrews KT, Zukowska Z, Burnett MS. Chronic Stress, Atherosclerotic Lesion Development, and Temporal Patterns of Cytokine Release. Sep 2010. Submitted to Stress.

• Andrews, JA. Stress, Infection, and Atherosclerosis. (Doctoral Dissertation, Georgetown University School of Medicine, Department of Physiology and Biophysics, June 2008).

• Najafi AH, Aghili N, Tilan JU, Andrews JA, Peng X, Lassance-Soares RM, Alderman LO, Abe K, Li L, Kolodgie F, Virmani R, Zukowska Z, Epstein SE, Burnett MS. A Novel Mouse Model Developing Stress-induced Complex Atherosclerotic Lesions Including Inflammation, Necrotic Core, and Intraplaque-Hemorrhage/Neovascularization. Circulation. Submitted Feb, 2012.

• Burnett MS, Lee CW, Kinnaird TD, Stabile E, Durrani S, Dullum MK, Devaney JM, Fishman C, Stamou S, Canos D, Zbinden S, Clavijo LC, Jang GJ, Andrews JA, Zhu J, Epstein SE. The potential role of resistin in atherogenesis. Atherosclerosis. 2005;182(2):241-248.

• Zbinden S, Clavijo LC, Kantor B, Morsli H, Cortes GA, Andrews JA, Jang GJ, Burnett MS, Epstein SE. Interanimal variability in preexisting collaterals is a major factor determining outcome in experimental angiogenesis trials. Am J Physiol Heart Circ Physiol. 2007;292(4):H1891-H1897.

• Womble MD, Andrew(s) JA, Crook JJ. 17beta-Estradiol reduces excitatory postsynaptic potential (EPSP) amplitude in rat basolateral amygdala neurons. Neurosci Lett. 2002;331(2):83-86.

• Williams D, Andrews JA. The physiological effects of wearing chemical protective clothing, taking diphenhydramine, and exercising. Pending BUMED approval, submitted to Military Medicine.

• Devaney JM, Robert SL, Gordish-Dressman H, Kaufman DJ, Adenika RJ, Andrews JA, Jang G, Lindsay J, Pichard AD, Satler LF, Kent KM, Waksman R, Howard BV, Epstein SE, Burnett MS. PPARγ2 Pro12Ala Polymorphism is Associated with Coronary Artery Disease and Myocardial Infarction in Women. The FASEB Journal. 2007;21:lb356.

• Andrews J, Andrews KT, Li L, Zukowska Z, Burnett MS. Chronic stress exacerbates atherosclerotic lesion development and causes Increased NPY and cytokine release. NPY Meeting 2007. Japan

• Andrews J, Andrews KT, Kuo L, Zukowska Z, Burnett MS. Stress increases circulating resistin levels: implications for cardiovascular disease. FASEB Poster Presentation 2006.

• Andrews J, Andrews KT, Zukowska Z, Burnett MS. Chronic Stress Induces a Pro-Inflammatory Response: Implications for Cardiovascular Disease. AHA Meeting 2007.

• Andrews JA. Peripheral Cells and the Central Nervous System: Potential mechanisms of neurodegeneration. AMSUS Conference 2009.

• Williams D, Andrews JA. The physiological effects of wearing chemical protective clothing, taking diphenhydramine, and exercising. The Society for Human Performance in Extreme Environments.

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