Curriculum Vitae

Tarak R. Sharma

Address: **** *. *******, *** ***, Wichita, KS 67207

Phone: 316-***-**** (Home); 646-***-**** (Cell) e-Mail: h4x28t@r.postjobfree.com

Field of Specialization: Biochemical Pharmacology, Analytical Biochemistry

. Experienced research investigator and trainer.

. Experience in clinical as well as in basic research.

. Expertise in analysis, interpretation and presentation of scientific concepts and data.

. A problem solver who believes in using common sense approach.

. Significant experience in research administration and regulatory affairs.

Work Experience: June 2006- August 2010 Research Scientist, Department of Biochemistry, Downstate Medical Center, Brooklyn, New York

Performing basic research in biochemical pharmacology and day-today management of the laboratory.

Technical Expertise at supervisory level in radioimmunoassay (RIA), Enzyme Linked Immunoassay(EIA), Spectrophotometry, Spectrofluorometry, HPLC and GC/MS.

Jan 1998-May 2010 Adjunct Assistant Professor or Associate Professor

Department of Chemistry at:

Long Island University at Brooklyn Campus, Brooklyn, New York.

College of Staten Island, Staten Island, New York.

Boro of Manhattan Community College, New York, New York.

Teaching undergraduate classroom and laboratory courses in Chemistry.

September 1997- January 1998 Laboratory technologist/Laboratory manager Staten Island University Hospital, Staten Island NY 10305 Qualitative and quantitative analysis of body fluids. T. Shasrma, CV Page two…….

September 1996- November 1996 Director, Toxicology California Skin Research Institute, San Diego, CA Assessment of adverse effects of drugs in clinical trials. Preparation of reports for FDA regarding the safety of drug under investigation. March 1993-Sept 1996 Laboratory technologist/Research consultant Staten Island University Hospital, Staten Island NY

Qualitative and quantitative assay of body fluids, quantification of various parameters including therapeutic and toxicological indicators, supervision of clinical research. September 1990-February 1993 Assistant Professor Department of Medicine, SUNY Health Science Center, Brooklyn, NY 11203 Laboratory and clinical research on diabetes. Taught Pharmacology toPGY-1 and PGY-2 residents.

December 1987-September 1990 Instructor Department of Psychiatry, SUNY Health Science Center, Brooklyn, NY 11203 Laboratory and clinical research on various psychiatric disorders. Taught Psychopharmacology to PGY-1 and PGY-2 students. Served as the Deputy chair of the IRB at Kingsboro Psychiatric Center, New York.

September 1985-December 1987 Department of Biochemistry, SUNY Health Science Center, Brooklyn, NY 11203

Laboratory research on influence of opiates on catecholamine secretion.

Research Interest: 2006-Present Downstate Medical Center, Brooklyn, NY Sexual dimorphism in pain perception. 1996-1997 California Skin Research Institute, San Diego, CA Adverse effects of cosmetic products in humans. 1993-1996 Staten Island University Hospital, Staten Island NY 10305

Laser enhanced effect of Doxorubicin, on an anticancer compound.

Lead toxicity in children of Staten Island.

T. Sharma, CV page three……..

1990-1993 Department of Medicine, SUNY Health Science Center, Brooklyn, NY 11203

Enhancement in insulin release by using various chemical agents.

Role of prostaglandins in glomerular filtration rate(GFR) in Type 2 Diabetes.

1987-1990 Department of Psychiatry, SUNY Health Science Center, Brooklyn, NY 11203

Role of acetylcholine in Alzheimer’s Disease.

Role of Alzheimer’s Disease Assistance Centers in helping families to cope

with the clinical condition.

1985-1987 Department of Biochemistry, SUNY Health Science Center, Brooklyn, NY 11203 Role of catecholamines and related enzymes in modulation of opiate release. 1983-1985 Department of Pharmacology, SUNY Health Science Center, Brooklyn, NY 11203 Study of catecholamines release using various modifying agents. 1973-1980 Study of catecholamines and related enzymes during health and disease with special reference to stress disorders. Doctoral dissertation submitted to Banaras Hindu University, Varanasi, India. Received the degree of Doctor of Philosophy. Education: Ph.D. Biochemistry 1980 Banaras Hindu University, Varanasi, India. M.Sc. Biochemistry 1973 Banaras Hindu University, Varanasi, India. B Sc. Chemistry 1971 Tribhuwan University, Kathmandu, Nepal. References:

1. Dr. Alan Gintzler, Professor of Biochemistry at Downstate Medical Center,

Brooklyn, NY.

Tel: 718-***-****

2. Dr. Nai-Jiang Liu, Assistant Professor at Downstate Medical Center, Brooklyn, NY

Tel: 718-***-****

3. Dr. Azeddine Bensalem, Chairman, Chemistry Department, Long Island

University, Brooklyn, NY

Tel: 718-***-****

List of Publications

1) S. K. Pandey, G. C. Prasad, T. R. Sharma, V. Rai and K. N. Udupa. Biochemical estimation of certain hormones, their inactivating enzymes and histological changes in their target endocrine glands after trauma. In: 5th Int. Conf. of Endocrinol., July 1975(London). Supplemented in Clinical Endocrinology. Backwell Scientific Publications(London).

2) K. N. Udupa, G. P. Dubey, R. Prasad, T. R. Sharma, R. H. Singh and J. P. N. Chansouria. Studies on body constitution and thyrotoxicosis. In: 7th Ann. Conf. of Soc. Nucl. Med., Calcutta, India, 1975.

3) F. H. Sarkar, S. S. Hasan, R. Prasad, T. R. Sharma, M. D. Verma, R. H. Singh, J. P. N. Chansouria and K. N. Udupa. Role of certain biogenic amines in gastric ulcer and its prevention by indigenous drugs. Quart. J. Surg. Scs. 12(2) : 108, 1976.

4) S. S. Hasan, F. H. Sarkar, T. R. Sharma, G. C. Prasad, G. C. Pant and K. N. Udupa. Response of adrenal gland to whole body Co60 irradiation. Ind. J. Exp. Biol. 15: 513, 1977.

5) J. P. N. Chansouria, T. R. Sharma, R. Prasad and K. N. Udupa. Studies on adrenal medullary function in certain stress disorders. Int. Seminar on stress, in Health and Disease. Varanasi, Feb., 1977, Quart. J. Surg. Scs. 13(3&4), 1977.

6) J. P. N. Chansouria, R. Prasad, T. R. Sharma, G. P. Dubey and K. N. Udupa. Studies on body constitution and thyrotoxicosis. Scientific Contribution, Vol. II (published by Medical Research Center, Bombay Hospital Trust, India), 1977.

7) S. K. Pandey, G. C. Prasad, V. Rai, T. R. Sharma and K. N. Udupa. A note on certain biochemical changes after fracture in dogs. Ind. J. Anim. Sci. 47 (12) : 851, 1977.

8) R. C. Gupta, T. R. Sharma, G. C. Prasad and K. N. Udupa. Neurohumoral response following psychic stress in rats. Ind. J. Exp. Biol. 16 : 614, 1976.

List of Publication Contd……….

9) S. K. Pandey, G. C. Prasad, V. Rai, T. R. Sharma and K. N. Udupa. Influence of immobilization on certain biochemical responses after fracture in dogs. Ind. vet. J. 55 : 893, 1978.

10) T. R. Sharma, J. P. N. Chansouria and K. N. Udupa. Alterations in urinary VMA levels following cigarette smoking, coffee drinking and alcohol consumption. Ind. J. Physiol. Pharmacol. 24(3) : 240, 1980.

11) T. R. Sharma and A. R. wakade. Calcium-dependent secretion of catecholamines following exposure of the rat adrenal gland to hypertonic solution. Paper presented at the meeting of American Society for Pharmacology and Experimental Therapeutics, Indianapolis, USA. Pharmacologist 26(3): 160, 1984.

12) A. R. wakade, T. R. Sharma, and T. D. wakade. Failure of alpha-adrenergic agents to modify catecholamines secretion evoked by nicotine or splanchnic nerve stimulation. Paper presented at meeting of ASPET, Indianapolis, USA. Pharmacologist 26(3):159, 1984.

13) A. R. wakade, T. R. Sharma, and T. D. Wakade. Facilitation of neurally evoked secretion of catecholamines from perfused rat adrenal gland by tetraethylammonium. Soc. for Neuroscience. Abstract, 10, 277, 1984.

14) A. R. Wakade, R. K. Malhotra, T. R. Sharma and T. D. Wakade. New evidence in favor of reutilization of chromaffin granules of the isolated adrenal gland of the rat. Fed. Proc. 44(5), 1719, 1985.

15) T. D. wakade, R. K. Malhotra, T. R. Sharma and A. R. wakade. Can voltage sensitive calcium channels of the rat chromaffin cells be opened at the resting membrane potential? Soc. Neuroscience. Abstract, 11, 973, 1985.

16) T. R. Sharma, T. D. wakade, R. K. Malhotra and A. R. Wakade. Lack of desensitization of voltage sensitive Ca channels of the rat adrenal medulla. Pharmacologist 27(3), 206, 1985.

17) T. R. Sharma, T. D. wakade, R. K. Malhotra and A. R. wakade. Secretion of the catecholamines from perfused adrenal gland of the rat is not regulated by alpha adrenoreceptors. Europ. J. Pharmacol. 122, 167, 1968.

18) A. R. Wakade, R. K. Malhotra, T. R. Sharma and T. D. Wakade. Changes in tonicity of perfusion medium cause prolonged opening of calcium channels of the rat chromaffin cells to evoke explosive secretion of catecholamines. J. Neurosci. 6(9), 2624, 1986.

List of Publications Contd…….

19) T.R. Sharma, W. C. Chan and A. R. Gintzler. Effect of chronic naltrexone administration and its withdrawal on the regional activity of neurons that contain norepinephrine, dopamine and serotonin. Brain Res. 442, 379, 1988.

20) P. Giacomazzi, T. R. Sharma, and H. E. Lebovitz. Desensitization of insulin secretion does not occur with all insulin secretogogues. Society of Endocrinology meeting, 1992.

21) J. D. Coplan, T. R. Sharma, L. A. Rosenblum, S. Friedman, T. Bassoff, R. Barbour and J. Gorman. Effects of sodium lactate infusion on cisternal lactate and carbon dioxide levels in nonhuman primates. Am. J. Psychiatry 149(10), 1369, 1992.

22) K. W. Lanks, J. P. Gao and T. R. Sharma. Photodynamic enhancement of doxorubicin cytotoxicity. Cancer Chemother. Pharmacol. 35, 17, 1994.

23) S. Chakrabart, Nai-Jiang Liu, James E. Zadina, T. Sharma and Alan R. Gintzler. Pleiotropic opioid regulation of spinal endomorphin 2 release and its adaptations to opioid withdrawal are sexually dimorphic. J. Pharmacol. Exp. Therapeutics. Published on Oct 4, 2011. JPET ID: 186874

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