Scientist / Manager Scientist
Resume:
Dr. Prakash. G
Email: *******.*******@*****.***
*******.*@*******.***
Present Address:
Dr. Prakash G.
Research Scientist
Department of Toxicology
Teratology Section
Advinus Therapeutics Ltd.
TATA Entreprise
Post Box No. 5813, Plot Nos. 21 & 22
PEENYA II Phase,
Bangalore – 560058, India
Mob- +919*********
Permanent Address:
Dr. Prakash G.
S/o Gopalappa.G
146/7, High School Extension
K.E.B 1st Cross
Honnali, Davanagere.
Karnataka - India
Ph- +918*********
Personal Data:
Name : Prakash G.
Father’s Name : Gopalappa G. Mother’s Name : Nagarathna
Date of Birth : 16-02-1981 Nationality : Indian
Status : Unmarried
Contact number: +919*********
Languages known: Kannada,
English, Hindi.
Objective
Seeking a challenging opportunity to be a part of a Toxicology team as an in vivo Mutagenicity, Teratology, Reproductive toxicologist and contribute to achieve research goals in a team environment.
Research Interest
Strong inclination towards pre clinical toxicological screening of drugs, vaccines and agro-pesticides, designing of protocols based on the nature of compounds with the international standards.
Work experience
Working as Associate Research Scientist, since from January 2010 to present. Teratology Section, DSA, Advinus Therapeutics Ltd, Bangalore.
Assisted in Various studies related to Micronucleus studies, Chromosomal aberration studies, Teratology(Rats & Rabbits), and Reproductive toxicology studies (Segment- I & RP G2), and other Acute and chronic studies.
Assisted and co authors for Standard operating procedures.
Research experience
Four months Research Training in TATA MEMORIAL CENTRE, Advanced Centre For Treatment, Research & Education In Cancer (ACTREC). Navi-Mumbai. MS.
Four years of Research experience in the field of Toxicology, Genotoxicology and Pharmacology, Department of Applied Zoology, Kuvempu University,
Teaching experience
Two years of teaching in the Department of Zoology, for undergraduate students. Sahyadri Science College, Shimoga.
Guided 8 undergraduate and 5 post graduate students (Aug 2006 to Aug 2009) for the project work involving toxicology and pharmacology fields.
Awards & Honours
Nominated as CPCSEA link Nominee, Ministry of environment and forests, India, for the Bio-needs Laboratory animals & preclinical services.
Nominated as Scientist from outside the Institute, CPCSEA, Ministry of environment and forests, for the IEAC of Adichunchanageri institute of Pharmacy, Belluru, Mandya.
Best poster presentation in national conference “Biotechnological strategies for Conservation of Biodiversity” Department of Applied Zoology, Kuvempu University, Shankaraghatta. Dated: 13-15th March 2008.
Education
Ph.D., “Investigation of bioactive components from Dioscorea pentaphylla from mid western of ghats of Shimoga”2011.
M.Phil., (Toxicology) “Anti genotoxicity of caffeine on alkylating agents on Drosophila malanogester (in vivo)”. 2007.
M.Sc., Applied Zoology (First class, 65.27 %), Kuvempu University, Shankaraghatta, Shimoga, Karnataka, India. 2004.
B.Sc. CBZ (First class, 60.4%), D.V.S. College, Kuvempu University, Shimoga, Karnataka, India, 2002.
Computer programmes
Database search software such as SciFinder. Graph Pad & SPSS SPG-4.0 (Statistical Package for Social Sciences) for biological data analysis, MS Word, Excel, Power Point.
Professional memberships
The cytometry society (1098)
Laboratory animal scientist’s association ( LASA-2192)
Society for Applied Zoologists (SAZ)
People for Animals (KNT.201245)
Society of toxicology (STOX- India).
Strengths
Confidence, Accepting Challenges.
Adaptability, Concentrating Ability.
Hardworking and committed to excellence.
Self learning ability of new skills.
Ability to work well independently and as a team member.
Ability to Work effectively with diverse groups of peoples.
Strengths
Protocol development for GLP, and Non GLP studies.
Stability and Homogeneity of the Test Item in the Vehicle.
Dose Formulation Analysis by using analytical techniques (HPLC).
Conducting of GLP studies according to OECD, ICH, OPPTS, Y- guidelines and other guidelines.
Electrophoresis, SDS, PCR, ELISA and Chromatographic techniques.
Protein Purification from plant sources. Enzyme assays, Immuno-precipitation. Ultra centrifugation, Dialysis, Ammonium sulphate / Acetone precipitation of proteins.
Molecular techniques for diagnosis of rodent pathogens, by Serological tests like Complement fixation(CF), Haemagglutination inhibition test(HAI) Indirect fluorescent antibody test( IFA) ELISA, PCR based assay( DNA & RNA amplification).
Handling of laboratory animals {Mice. Rats, Rabbits, Guinea pig, Hamster & Drosophila}.
Animal cell culture (Cancer Cell lines) & Handling of Microorganisms.
Biochemical analysis of protein, lipid, antioxidants, Nucleic acids and carbohydrates.
Screening of Drosophila and Mice Mutagenicity assays. {Dominant Lethal, Somatic Mutagenic Recombination Test (SMART). Sex Linked Recessive Lethal Test (SLRL)}.
Screening of natural compounds from plant source (Soxhlet).
Handling HPLC, UV- spectrometer, colorimeter, flame photometer, Histological techniques and etc.,
Collection of samples like Blood, tissues from lab animals, Tumor grafting,
List of publications/ communicated
Prakash.G., Ragavendra.S., Ramesh. C.K., Manjunath.K.S. and Paramesh. M., 2008. Antibacterial activity of some Euphorbiaceae weeds against pathogens. ICFAI journal of Life sciences. Vol-2, No-2, Page No 36-40.
Hosetti B. B., Pramod Kumar M. P. M., Raja Naika H., Ujwal P., and Prakash G. 2009. “Modulation of the micronucleus formation by total extracts from leaves, bark and seeds of Pongamia pinnata”, IJBPS, Global sciences publication.
Prakash.G and B.B.Hosetti. “Investigation of antimicrobial properties of Dioscorea pentaphylla from mid western ghats” 2010. Scientific world. Vol. 8, No. 8.
Prakash. G, Manjunatha H, Sabesan. M, Hosetti. B. B. “Protective effect of caffeine against cyclophasphamide induced genotoxicity in vivo”. 2011. Journal of LASA.
Prakash.G. Hosetti. B.B and Sabesen. M “Antigenotoxic effect of caffeine on genotoxic dose of methyl methanesulfonate (MMS). in vivo” Toxicology International (Revised and submitted)
Prakash.G. Hosetti. B.B and M Sabesen “Antigenotoxic effect of pre-treatment of caffeine on genotoxic dose of alkylating agent (EMS) in vivo”. Journal of Bioscience (Revised and submitted).
Prakash.G., Dhananjya.S.G and Hosetti. “Protective effect of Dioscorea pentaphylla on wing primordial cells of Drosophila melanogaster”. Journal Environmental Toxicology And Pharmacology (Communicated).
Prakash. G and Hosetti B.B. In vitro Antioxidant and Free Radicals Scavenging Activity of Dioscorea pentaphylla. International Journal of Pharmaceutical Sciences. (Communicated).
Prakash. G Dhananjaya B. and Hosetti B.B. Diosgenin- A Potent molecule for anti-inflammatory from Dioscorea pentaphylla. Plant medica (Communicated).
Conferences/ symposium attended& presented
2004: National Level Symposium on “Trends in Radiation Biology” Oct, 17 -19, Dungar College, Bikaner, Rajasthan.
2004: State Level Symposium “DNA Past, Present and Future” DVS College of Arts and Science, Shimoga, Karnataka.
2005: National Level Symposium on “Environmental Pollution and Ecotoxicology” 4th-5th of March, Nijalingappa College, Bangalore. Paper presented Influence of monocrotophos on neuro-endocrine regulating activities of Barytelphus canicularis (W.).
2005: National conference on “Intellectual property rights” 21 Dec 2005. Jawaharlal Nehru National College of Engineering. Shimoga, Karnataka.
2005: Workshop on “Frontiers areas of physics” Nov -2005. Department of physics. Jnanashyadri, Shankaraghatta, Karnataka.
2006: National conference on “Fronteries of plant pathology” at Department of Applied Botany, Kuvempu University, Shimoga, Karnataka. 23-25, Oct-2006. Paper Presented “Investigation on antimicrobial property of crude extract of Dioscorea pentaphylla of western ghats”.
2006: International Conference in Zoology “INCOZ-2006” at Bangalore University, Bangalore.19-22 November 2006.Paper Presented Genotoxicity studies of Methylmethanosulfonate on Drosophila melanogaster.
2006: National Seminar on “Recent Advances in Animal Ecology” at Department of Zoology, J.M.J.College Achary Nagarjuna University, Tenali. 23-24th November 2006 Paper Presented- Habit distribution of Drosophila of Shimoga city and Lion Safrari of Western Ghats,
2007: Indo-Australian Conference on Human variations and pharmocogenomics at Manipal University, Manipal. 17-19th March 2007.Paper presented- Regulation of caffeine on Vinblastine induced cyto-genotoxicity in swiss albino mice.
2007: National Seminar on “Emerging areas in chemical and biological sciences. at Department of Chemistry, Kuvempu University, Shankaraghatta. Dated:23-24th March 2007. Paper presented- Evaluation of Anti Microbial activity from different parts of Pongamia pinnata
2007: National Seminar on “Emerging areas in chemical and biological sciences. at Department of Chemistry, Kuvempu University, Shankaraghatta. Dated:23-24th March 2007. Paper presented- Compartivie study of anti bacterial activity by Cow urine of Hallikar and Holstein, Freistain (HF) breads of Karnataka.
2008: National Seminar on “Biotechnological strategies for Conservation of biodiversity” Department of Applied Zoology, Kuvempu University, Shankaraghatta. Dated:13-15th March 2008. Paper presented- Antigenotoxic effect of pre-treatment of caffeine on genotoxic dose of alkylating agent (EMS). in vivo.
2008: National Seminar on “Biotechnological strategies for Conservation of Biodiversity” Department of Applied Zoology, Kuvempu University, Shankaraghatta. Dated:13-15th March 2008. Paper presented- In vitro evaluation of antioxidant activity of crude extracts from a medicinal plant, Dioscorea oppositifolia.
2008: 28 th Annual conference of STOX and International Symposium on “Monitoring and modulating global resources of environmental and food contaminates; Nature versus Chemicals. Held at GADVASU. Ludhiana. Punjab. on 16-18 of 2008. Paper presented - Antigenotoxic effect of caffeine on genotoxic dose of methyl methanesulfonate (MMS). in vivo.
2009: Prakash. G , Manjunatha H, Sabesan. M, Hosetti. B. B 96th The Indian Science Congress held at North-Eastern Hill University, Shillong on January 3-7. “Protective effect of caffeine against vinblastine induced genotoxicity in vivo”
2009: Prakash. G, Manjunatha H, Hosetti. B. B., “Diosgenin: A potent anti-inflammatory molecule from Dioscorea pentaphylla (Dioscoreaceae)” held at S.V. University, Tirupati on July 25-27. ‘International symposium on environment pollution, ecology and human health’ Presented
2009: Prakash. G, Manjunatha H , Hosetti. B. B. “Study on antigenotoxic effect of Dioscorea pentaphylla extracts on drosophila wing primordial cells” held at S.V. University, Tirupati on July 25-27. ‘International Symposium on Environment Pollution, Ecology and Human Health’ Presented.
Refernces
Dr. B.B. Hosetti
Professor
Dept. of Zoology
School of Biosciences
Jnansahyadri
Kuvempu University,
Shankaraghatta - 577 451
Shimoga (Dist.), Karnataka
Cell : 984-***-****
E-mail : ********@*****.**.**
Dr. Harpal Singh Sandhu
Professor & Head
Dept of Veternary Pharmocology and Toxicology,
College of veterinary science
Guru Angad Dev Vetrinary & Animal Sciences University
Ludhiana-141004
Cell 098********
E mai: **********@*****.**.**
Dr. Aravind Ingle
Officer in charge
Animal house and Histology
ACTREC, Tatamemorial Centre
Kharghar, Navi Mumbai-410210
Cell – 098********
E-mail: ******@******.***.**
Dr. K. S Rao
Associate Vice President - Business Development
Emeritus Member of SOT
Editor-In-Chief of Toxicology International Journal
Advinus Therapeutics Ltd
21 & 22 Peenya IInd Phase, Peenya Industrial Area. Bangalore 560 058
Mobile: +91-988-***-****
**.***@*******.***
I hereby declare that the above-mentioned information is true to best of my knowledge and I bear the responsibility for the correctness of the above-mentioned particulars.
Signature of the Candidate
( PRAKASH.G )
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