Bioinformatics Analyst/ Programmer

RONAK SHAH

**** *** *******, *** ***, FAIRFAX, VA. 22031

EMAIL: ****.****@*****.*** MOBILE: 917-***-****

OBJECTIVE

To obtain a challenging position at a biotechnological research organization that would provide experience in the challenging interdisciplinary field of Computational Biology and Systems Biology.

EDUCATION

-> M.S., Bioinformatics and Computational Biology. December 2010

George Mason University, Fairfax, VA, GPA 3.88

-> B. Tech.,Bioinformatics. June 2008

Dr.D.Y.Patil University, Navi Mumbai, Maharashtra, India. GPA: 3.84 (WES Equivalent)

-> Certification – GENES to DRUGS: In-Silico Drug Discovery. June 2006

Institute of Bioinformatics and Applied Biotechnology, Bangalore, India.

GCG, Insight II, Cerius II and Catalyst.

TECHNICAL SKILLS

Computer Languages: Proficient in Perl, Python, MySQL, R statistical package, Familiar with C, C++, Java, Visual Basic, HTML.

Operating Systems: Expert in Windows 9x/2000/XP/Vista, Proficient in Mac, Unix, Linux.

Design Programs: MS Office Suite, MS Access, MySql Workbench.

Languages: Fluent in English, Hindi, Marathi, and Gujarati.

Software’s: ClustalW, EMBOSS, SPDB Viewer, RASMOL, CHEM SKETCH, MEGA4, Topd/fmts, Weka, BLAST.

Procedures: Homology modeling using Swiss PDB viewer, Database creation and usage, Computational methods for sequence analysis, molecular modeling and computer aided drug design.

WORK EXPERIENCE

Graduate Teaching Assistant, George Mason University, Fairfax, Virginia. September 2008 to Present

-> Provide support for students and faculty of a technical department within a health and human service college within a large state university.

-> Instruct students on the usage of Virtual IV and Virtual Phlebotomy stimulation equipment.

-> Electronically grading the exams conducted by teaching faculty at the college of health and human service.

Bioinformatics Research Assistant, George Mason University, Fairfax, Virginia. May 2009 to May 2010

-> Aid head researcher in bioinformatics laboratory within a neurological research center on state university campus.

-> Utilize bioinformatics tools such as Muscle, topd/fmts and Rate4Site to do evolutionary analysis of dopamine d2 receptors by doing multiple sequence alignment and statistical analysis of phylogenetic trees.

ACADEMIC PROJECTS

Improving Features for the Bovine Hap Map Database Interface October 2010

-> Currently working on the project for completion of Independent Study.

-> Understand about the variation within a given species and analysis using SNP Genotypes for determining the linkage disequilibrium, haplotypes, and signatures of selection.

-> Learn about web based programming for displaying various data types by querying from a database.

SVM based method to assess the reliability of protein-protein interactions October 2009

-> Worked as a team of three for the class project required for the successful completion of the class Biological Data Mining.

-> Using an SVM based approach to generate a model that is built on sequence and non-sequence based information of the interacting proteins. This model is used to assess the reliability of given protein-protein interactions.

A Survey of De Novo Short Read Sequence Assemblers May 2009

-> Worked as a team of two for the class project required for the successful completion of the course Biological Sequence Analysis.

-> A survey of various assemblers and comparative study on a common dataset was performed using algorithms, Edena, Velvet and, VCAKE. These assemblers were evaluated using some predefined metrics like number of contigs, Maximum contig length, Mean contig length, N50, N80 and runtime.

Protein Structure Overlap May 2009

-> Completed the class project required for the successful completion of the course Advanced Bioinformatics Programming.

-> Protein structure overlap was performed using the superposition algorithm and its comparison of the protein structure is done with the help of UCSF Chimera

Database Creation and Interaction October 2008

-> Completed the class project required for the successful completion of the course Bioinformatics Programming.

-> Made a database of human genes with HUGO Gene Nomenclature using MySQL and provided it a web interface for searching it using Perl and CGI.

Characterization of Entmopathogenic Fungus fusarium moniliforme June 2008

-> Completed three month intensive thesis project required for undergraduate degree at a Bhabha Atomic Research Center (BARC), a government atomic research laboratory.

-> Characterized the fungus fusarium moniliforme with respect to its environmental and physiological conditions.

-> Developed C++ program to identify optimal fungal growth determined by the data obtained from the experimental results.

PUBLICATIONS

-> Ronak Shah, Nadine Kabbani & Huzefa Rangwala (2009). Co-evolution in the N-terminal region and the third intracellular loop of the Dopamine D2 receptor, The Biological Bulletin.(in press)

PROFESSIONAL CONFERENCES

-> Computational Drug Discovery In Pharma R & D, by School of Pharmacy & Technology Management, SVKM’s NMIMS University, Mumbai. August 2007

-> International Conference on Chemoinformatics, National Chemical Laboratory, Pune, India. January 2007

-> Bioinformatics and Functional Genomics, Pondicherry University Bioinformatics Centre, Pondicherry, India. February 2006

-> Bioinformatics and Drug Design, SIES Institute of Environmental Management Navi Mumbai, India. March 2005

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