Technician Assistant
Resume:
Jennifer Spencer-Pierce
** ******* ********* #**** • Derry, NH 03038
*********@*******.***
LinkedIn.com/in/JenniferSpencerPierce
SUMMARY OF QUALIFICATIONS
* An efficient and highly skilled scientist with proven success working in diverse research
environments, including biotech, start up and large pharmaceutical companies.
* Certified laboratory animal technician with extensive knowledge and experience working with animal models in pharmacokinetics and pharmacology.
* Motivated and focused, able to work independently and/or as part of a team to complete tasks within demanding deadlines. Possess excellent organizational and communication skills that enhances the production of quality science.
* Energetic team member who is eager and determined to learn new skills and techniques quickly in a
challenging and engaging environment.
RELEVANT SKILLS
Animal Dosing (IV, PO, IM, SC, IP) gavage
Scheduling/planning/coordinate
Clinical observation
Collaboration
Microsoft Office
Tissue harvesting
In Vivo experimentation Imaging techniques
Surgical skills/aseptic technique
Record keeping/E-Notebook
Study coordination
Liaison
IACUC protocol writing
Formulation preparation
Study management
Small molecule
Proteins
Data analysis/archiving
Basic cell culture
Sample tracking/receiving
PROFESSIONAL EXPERIENCE
Wyeth Pharmaceuticals, Andover, MA 2006--2011
Company acquired by Pfizer in October 2009
Worked as a Scientist II (Senior Associate Scientist, Pfizer) in the Pharmacokinetics group as an animal study coordinator supporting and scheduling PK/PD studies for up to 10 principal investigators, Veterinarians and technical staff for Oncology, Inflammation and Cardiovascular and Metabolic Diseases and acted as a liaison/point of contact for all studies and projects.
* Assisted in implementing new in vivo imaging technology for testing of biologics.
* Rodent handling, dosing, serial bleed sample collections.
* Assisted with I-125 radio labeled tissue and serum samples by measuring drug concentrations through use of gamma counter.
* Planned, organized, coordinated and help write study protocols for PK studies by meeting with PI’s.
* Helped Andover become a star site for OSHA VPP inspection and received an Above and Beyond
award.
* Authored 3 IACUC protocols for new animal models for PK (guinea pig, Non human primate and 5/6
nephrectomy rat).
* Amended institutional IACUC protocols when necessary to ensure PK studies were conducted under
humane and ethical standards using GRANITE software.
* Receive, track and transfer samples to bioanalytical scientists for analysis.
* Make dose formulations for PK studies (small molecule and biotherapeutics).
* Handled animal inventory and track/schedule PK studies at other Wyeth sites/external sites as well as compiled and calculated metrics for year end reports.
* Acted as liaison to PIs and various departments/groups, point of contact role on many projects.
* Prepared and presented a poster at NEDMDG “In Silico Prediction of Compound Bioavailability and
Exposure in Rodents.”
* Helped establish a new micro bleed technique for a “one mouse, one PK” model--nominated for “3
R’s” award which greatly reduced animal numbers used in a PK study by 90%.
* Established a 5/6 nephrectomy rat surgical model for renal failure.
* Conducted NHP, rat and mouse glomeruli isolation procedures by working with external vendors.
* Animal handling, dosing, sample collection for various projects including neuroscience, oncology and Inflammation to advance compounds to pre-selection phase.
* Formulation of compounds for dosing to animals.
* Conducted basic cell culture techniques to support various projects (cell growth, maintaining cell colonies, splitting cells, cell counting).
Paratek Pharmaceuticals, Boston, MA 2005--2006
Worked as a Scientist in the PK department establishing the PK lab and conducting in vivo PK studies.
* Established and implemented PK procedures for dosing and sample collection by writing SOP’s as
well as conducting PK studies.
* Computed data using WinNonlin software.
* Formulated compounds for dosing to the animals.
* Coordinated and organized animal requests for PK studies.
Scion Pharmaceuticals, Medford, MA 2003-2005
Company was dissolved October 2005
Worked as a Scientist in the electrophysiology department harvesting frog oocytes and injecting them with mRNA for the electrophysiologists.
* Responsible for the successful removal of oocytes from Xenopus laevis frogs through survival surgery techniques.
* Oversaw and trained new hires on handling and daily equipment maintenance of the Xenopus laevis
colony.
* Responsible for providing the electrophysiology group with ~2000-3600 healthy mRNA injected
oocytes per week.
* Handled and solved any oocyte health problems and implement a corrective action.
* Troubleshoot and resolve micro injector problems.
* Coordinated injection schedules and delegated work.
* Spent three months learning HPLC/mass spec and sample prep, saved company $20,000 in outsourcing
costs, received award for dedication and perseverance.
* Conducted rodent pain models, including acidic acid writhing model and automated formalin studies.
Vertex Pharmaceuticals, Cambridge, MA 2000--2003
Started as an Assistant Scientist working in the PK department conducting in vivo PK studies in rodents and was promoted to Associate Scientist in 2003.
* Performed jugular vein and carotid artery cannulation surgery in rats for PK studies.
* Formulate compounds and conduct PK/ADME studies to enable the selection of drug candidates
toward the support of drug development.
* Presented a department wide, one hour presentation on “What Happens in the Animal Facility.”
* Appointed to represent the PK department at IACUC meetings.
EDUCATION
Southern Connecticut State University, (graduate courses in Biology, including Immunology, Cancer Biology)
Bachelors of Science, Quinnipiac College, Veterinary Technology
CERTIFICATIONS
American Association for Laboratory Animal Science, 2002, Certified Laboratory Animal Technician
MEMBERSHIPS
New England Branch, American Association for Laboratory Animal Science, 2011
American Association for Laboratory Animal Science, 2002-present (on and off membership).
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