Professor of Pathology; Director, Clinical Molecular Analysis Lab

David S. Strayer, MD, PhD

*** ********* ****, ******* ******, Pennsylvania 19073

*****************@*****.*** 610-***-**** (Home Phone); 610-***-**** (Home Fax)

215-***-**** (Cell Phone); 215-***-**** (Fax)

Physician/Scientist with Track Record of Accomplishment and Innovation

Developmental Therapeutics

Clinical Studies

Creative solutions and problem-solving

Integrative multidisciplinary project management and coordination

Evaluation of Medical Research and Analysis of Likely Effectiveness

Summary:

•Accomplished translational investigator and problem-solver with a strong history of devising, developing and delivering innovative solutions to difficult problems

•Adaptable organizer and leader, experienced in heading and participating in complex, multi-faceted and multi-talented groups to address critical priorities in therapeutics, diagnostics and organization

•Polished communicator excelling at cogent presentations in multiple languages

Experience:

Current Position

Professor, Department of Pathology and Kimmel Cancer Center, Thomas Jefferson University; Attending Pathologist, Thomas Jefferson University Hospital, Philadelphia, PA; June 1992-present

Investigative Accomplishments:

Established, directed and maintained NIH-funded translational therapeutics research laboratory with 18 federal and 8 non-federal grants, as Principal investigator (21) and co-investigator (5).

Achieved recognition in publishing 148 (to date) original, peer-reviewed publications, over 200 abstracts, 57 books, chapters, invited reviews and editorials

Pioneered novel and highly effective approaches to genetic transfer to several organs, including brain, liver, bone marrow, lungs

Devised and brought to fruition therapeutic strategies to treat acquired and inherited diseases of lung, liver, brain, hematopoietic and immune systems

Recognized as a leader in the field of developmental therapeutics by being named founding chair, NIH Gene and Drug Delivery study section

Developed and implemented solutions to important problems in therapeutics with innovative design of delivery vehicles, organ targeting

Awarded 6 U.S. patents

Pathology and Clinical Laboratory Achievements:

Developed de novo, and continue as medical director, Molecular Diagnostics Laboratory, Kimmel Cancer, to achieve CLIA laboratory certification and CAP accreditation

Established and served as medical director of clinical immunology laboratory, Hermann Hospital, Houston, TX

Over 30 years of service as diagnostic surgical and anatomic pathologist

Maintained Clinical Immunology laboratory as Medical Director

Prominence acknowledged by appointments as Senior Associate Editor of two major journals of Pathology, Laboratory Investigation and Human Pathology

Recognized by selection as editor of Rubin’s Pathology, a major English language text of Pathology

Organizational skills:

Created, organized and directed multi-investigator, multi-institutional, multi-disciplinary research consortia and conducted and participated in the execution of preclinical and clinical trials

Coordinated major institutional instructional program, involving dozens of faculty, interfacing with many segments of the institutional community

Built, led and maintained an independent and innovative translational therapeutics laboratory with a team of up to 15 postdoctoral and doctoral investigators

Directed successfully several major functioning departmental committees, coordinating recruitment of faculty and running major ongoing activities

Published Investigative Expertise:

Pathology

Infectious Diseases (HIV/AIDS, Hepatitis B, Hepatitis C)

Neurodegenerative Diseases (NeuroAIDS, Parkinson’s Disease, Alzheimer’s Disease)

Genetic Therapy (Gene Delivery, Gene Regulation)

Cancer Diagnosis and Treatment

Immunology and Immunopathology

Molecular Biology and Molecular Diagnostics

Clinical Trials

Participated in major international clinical trials in pulmonary medicine from pre-IND through completion

Organized and composed proposals for U.S. clinical trials of genetic therapy to treat HIV/AIDS

Problem solving: Effective in organizing teams and in solving scientific problems in several areas

Clinical–established a new clinical laboratory, through approval and accreditation

Research–Inventive application of therapeutics and assay design to circumvent important hurdles

Originated novel approaches to execution of clinical trials

Effective development of novel approaches to overcome hurdles in gene delivery

Organized virtually from scratch a major medical college course

Founding, maintaining and leading a diverse research laboratory

Consultative experience

Consulted for pharmaceutical and biotechnology corporations in the U.S. and Europe

Served as external advisor for academic research consortia

Testified as a medical advisor and expert for the defense in dozens of legal cases involving workplace safety, product liability and standard of care professional liability litigation

Advised U.S. Government agencies (U.S.E.P.A.) on environmental and medical toxicology

Communication Skills

Capable of preparing and executing presentations effectively and persuasively, written and oral

Facility with foreign languages: excellent command of French, good command of German and Italian, adequate skills in Spanish; lectured in France in French, and in Italy in Italian

Prior Experience:

Professor, Department of Pathology University of Texas, Houston, TX;

Associate Professor, Department of Pathology, Yale University, New Haven, CT;

Assistant Professor, Department of Pathology, University of California at San Diego, La Jolla, CA

Instructor, Department of Pathology, Washington University, St. Louis, MO

Education:

Resident in Pathology, Barnes Hospital and Washington University, St. Louis, MO

M.D., with honors, University of Chicago, Pritzker School of Medicine, Chicago, IL

Ph.D., Pathology (Immunology), University of Chicago, Pritzker School of Medicine, Chicago, IL

A.B., Chemistry, magna cum laude, Phi Beta Kappa, Cornell University, Ithaca, NY

Licensure/Certification:

Licensed Physician and Surgeon (active): Pennsylvania, MD-046970-L; California, G-41870

Certified in Anatomic Pathology, American Board of Pathology

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