Research Biologist
Resume:
Marisa Flaim
East Greenville, PA 18041
*********@*******.***
Summary
Research Biologist experienced in initiating and conducting preclinical studies in four different animal models for
a Fortune 500 firm as well as working as a large animal technician for a biotech company. Strengths include various
observation and measurement techniques, data management and communication with study directors, relevant departments
and peer biologists. Known for performing with integrity in an accurate, detailed, efficient manner, even under a
heavy workload.
Professional Experience
Merck & Co., Inc., West Point, PA 2002-2011
Staff Biologist, Toxicology – Safety Assessment (2004 – 2011)
Biologist, Toxicology – Safety Assessment (2002 – 2004)
Conducted a wide variety of preclinical animal studies in accordance with GLP’s and SOP’s using numerous dose formulation
administering techniques: oral gavage, capsule, nasogastric, subcutaneous, intramuscular and intravenous dosing.
Proficient in documenting observations (body weight, food consumption, ophthalmic, clinical signs, etc.) and collecting
various samples (blood, urine, ECG, etc.). Promoted to Staff Biologist in 2004.
Actively participated in functional group teams such as PPE closet stocking, prep room stocking, predrug bleeding team,
glassware inventory, ECG on-call assistance, animal enrichment and pipette calibrations which improved department
efficiency, accuracy and reliability.
Maintained effective daily communication with Study Directors and other biologists pertaining to any study related issues,
improving accuracy and quality of studies. Discussed clinical findings and dose concentrations increasing efficacy of
studies by having 90% or more of the test subjects reach study termination.
As member of equipment team, played a key role in the planning and execution of new automated dosing equipment by
validating the equipment’s accuracy, demonstrating to other biologists, distributing and collecting surveys, compiling
the data and presenting the results to the team in meetings. This resulted in a successful implementation of an automated
dosing system capable of delivering doses in microliters enabling the department to perform micro-dosing studies which
contributed to increased profit.
Pioneered study paradigms for Pharmacokinetic department. Conducted 90% of these rapid-paces studies, generated a
department checklist, and trained/mentored other biologists to run the remaining studies. This resulted in decreased
manpower costs and errors, increased accuracy and contributed to increased profit.
Conducted peer reviews for other biologists’ paperwork and studies. In addition, conducted mock studies and
gathered/presented information for facilitating social-housing of non-rodents, participated in three departmental
objective committees, trained biologists in procedures using updated computer systems and in laboratory techniques, all
of which improved the quality of team’s work, helped to minimize errors and achieved required timelines.
As part of a cost containment initiative, volunteered to cross-train in the Biologics Release Testing & Immunotoxicity
area, involving processes/techniques related to release testing for market or preclinical aspects such as: proficiency
in intraperitoneal and intracranial dosing to adult/suckling mice, intraperitoneal dosing to guinea pigs, pyrogen assay
for rabbits, cardiac bleeding for mice, gross examination of mice, guinea pigs and rabbits, dilutions or reconstitutions
of stock vaccines.
Lampire Biological Laboratories, Ottsville, PA 2002
Large Animal Technician
Oversaw and documented the daily animal husbandry for a wide variety of animal species and assisted with routine farm
requirements. Collected blood samples and delivered to either of the nearby biotech laboratories. Involved in the
testing of poultry subjects.
Education
Bachelor of Science, Large Animal Science, Delaware Valley College, Doylestown, PA
Cumulative GPA of 3.45
Technical Training
Working knowledge of Microsoft Word, Excel, Power Point, Outlook
PhAARME program and Burdick ECG equipment
Xybion computer system
Rodent Survival Surgery
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