Manager Quality Control

Location:

Sheridan, WY, 82801

Salary:

70000 to 100000

Posted:

August 04, 2011

Contact this candidate

Resume:

Umadevi Bhoga M.Sc & Ph.D

Sheridan, WY *****

Tel# 406-***-**** (mobile)

Ph: 307-***-**** (home)

Email: ******@*****.**.** or ********@*****.***

EDUCATION/TRAINING

Kakathiya University, India B.Sc (chemistry) 1989-1992 Biology, Zoology and Chemistry

Osmania University, India M.Sc (chemistry) 1993-1995 Chemistry

Dr. Reddy’s Research Foundation, India Senior Chemist 1995-1998 Basic Research Hyderabad, India Ph. D (chemistry) 2000-2005 Organic chemistry

University of Saarland, Germany Postdoctoral 2005-2007 Discovery of Anti cancer agents

University of Santiago, Spain Postdoctoral 2008 Total Synthesis of Pancratistatin, potential Anti Cancer agent

University of the Witwatersrand,

South Africa Postdoctoral 2008 Synthesis of Podophyllotoxin clans

Montana State University, USA Postdoctoral 2009 Methodology & Discovery of Drug Delivery entities

POSITIONS AND HONOURS

PROFESSIONAL EXPERIENCE

1995-1998 Senior Chemist, Dr. Reddy’s Research Foundation, Hyderabad, India.

August 2005-December 2007 Postdoctoral Fellow, Pharmaceutical & Medicinal Chemistry, University of Saarland, Germany

2008 Post Doctoral Fellow, Department of Organic Chemistry, University of Santiago, Spain

2009 Post Doctoral Fellow, Molecular Sciences, South Africa

2010 Post Doctoral Fellow, Department of Chemistry & Biochemistry, USA

Present Ph.D Chemist & Analytical chemist, Inter-Mountain Labs Inc, Sheridan, WY

2000 Senior Research Fellow Award, Council of Scientific and Industrial Research, India

2009 National Research Fellow Award from South Africa

2008 Distinguished Performance Award from Dr. Reddy’s Pharmaceutical R & D

India

2011 Invited Speaker from BABE 2011, 2nd World Science Congress, Pharmaceutical R & D summit

OTHER EXPERIENCES

2011 Peer Reviewer of Journal of Cancer Science & Therapy

2011 Peer Reviewer of Journal of Bioanalysis & Biomedicine

2011 Peer Reviewer of Journal of Bioequivalence & Bioavailability

2009 Invited Reviewer of European Journal of Medicinal Chemistry

Conferences attended:

International conference on heterocyclic chemistry, Jaipur, Rajasthan, India, December 2001

Bi-National conference, September 2008 in South Africa, Poster presentation

NRF (National Research Foundation) Award from South Africa

SELECTED PEER-REVIEWER PUBLICATIONS

1. Synthesis of seven membered aza sugars. Braj Bhushan Lohray*, Vidya Bhushan Lohray, Prasuna Guntupalli, M.A. Raheem, Umadevi Bhoga Indian Journal of Chemistry, 1999, 38, 1311-21

2. New synthesis of linear furoquinoline alkaloids. Umadevi Bhoga,* R. S. Mali and Srinivas R. Adapa* Tetrahedron Letters, 2004, 45 (51), 9483-9485

3. A new synthetic approach to enantiomerically enriched dihydrobenzofurans: use of a hydrolytic kinetic resolution and an intramolecular epoxide ring opening protocol using 1-benzyloxy-2-oxiranylmethylbenzenes. Umadevi Bhoga Tetrahedron Letters, 2005, 46, 5239-5242

4. Novel synthetic approach to N-aryl-4-(3-pyridyl)thiazol-2-amine and analogues using HMCM-41 as catalyst, and their biological evaluation as human platelet aggregation inhibitors. Umadevi Bhoga, European Journal of Medicinal Chemistry, 2007, 42(8), 1144-1150

5. Substituted 6-Phenyl-2-naphthols. Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1): Design, Synthesis, Biological Evaluation, and Pharmacokinetics. Sandrine Marchais-Oberwinkler, Patricia Kruchten, Martin Frotscher, Erika Ziegler, Alexander Neugebauer, Umadevi Bhoga, Emmanuel Bey, Ursula M ller-Vieira, Josef Messinger, Hubert Thole and Rolf W. Hartmann Journal of Medicinal Chemistry, 2008, 51, 4685–4698

6. World Patent No. 6051850 from Dr. Reddy's research Foundation

7. Anticancer Properties of an Important Drug Lead Podophyllotoxin Can Be Efficiently Mimicked by Diverse Heterocyclic Scaffolds Accessible via One-Step Synthesis Igor V. Magedov, , Liliya Frolova, Madhuri Manpadi, Uma Devi Bhoga, Hong Tang,§ Nikolai M. Evdokimov, Olivia George,# Kathy Hadji Gorgeou, Steffen Renner, Matthäus Geftic, Tiffany L. Kinnibrugh, Manuel Fernandes, Severine Van slambrouck, Wim F. A. Steelant, Charles B. Shuster,# Snezna Rogelj,§ Herbert Waldmann, Daniel Rauh, Willem A. L. van Otterlo, , , and Alexander Kornienko , Journal of Medicinal Chemistry 2011 (Press)

8. An Efficient Approach to 2-(m/p-Methoxybenzyl)-1-Oxo-1, 2-Dihydroisoquinoline-3-Carbaldehyde, via Base catalyzed Intra molecular Aldol Condensation of Dial Intermediate, Umadevi Bhoga*, Ricardo Alonso. Submitted for European Journal of Organic Chemistry 2011

9. Synthesis of Open-chain Pancratistatin Analogues Umadevi Bhoga1, Warren Thompson1 Alexander Kornienko2 and Willem A. L. van Otterlo1 Poster Presentation at BOCC Conference 2008, South Africa

At IML Inc, I worked on various analyses using GC-MS spectrometry.

Prior to the extraction, all the samples will be entered in to the PREP sheet from Omega LIMS system.

Extractions:

Every extraction contains 5 QC analysis (Quality Control with a MDL, method detection limit). They are method blank (MB), lab control sample (LCS), lab control sample duplicate (LCSD), sample Spike (MS), sample spike duplicate (MSD).

Weiging balance needs to be calibrated prior to soil extractions.

EPA method 3510_D (water extraction using seperatory funnel 500ml/volume)

EPA method 3550_D (Soil extraction using sonication)

Microvial extraction of water:

Halo acetic acids

EDB & DBCP (Dibromoethane and Dibromochloropropane) using 3511 EPA method

EPA method 5035 (soil extractions)

Prior to the analysis, all instruments would be calibrated. Instruments were calibrated every 12 hours.

After extracting the samples, analysed them for DRO (Diesel Range Organics or Hydraulic oils using 8015_D EPA methods on GM-MS/FID)

Analysis of haloacetic acids using 552.1 EPA Method on ECD (Electron Capture Detector)

Analysis of EDB & DBCP (halo alkanes) using 504 EPA method on ECD (Electron Capture Detector). This method was developed.

After the analysis, Data was processed and Data Entry in to the LIMS was the prior step to reporting to the clients.

Preparation of standard solutions, spike solutions, maintaing LOG book for these solutions, entering all the solutions data in to the LIMS system.

Maintaining Good Laboratory Practice, MSDS (Method Safety Data Sheet)

Successfully accomplishing Auditings.

In addition to this, I was involved in a research project from one of our clients, related to organic isolations and characterizations. I ha wriiten a 100 pages paper with manager Tom Patten.

All the extraction and analyses were performed within the client holding times to meet the customer satisfaction.

We have safety meeting every month. I had undergone fire extinguishing training.

SOP procedures were followed and revised during the development of the methods.

I am the happiest person to work on these analytical methods at IML.

You may feel free to contact the following references from my company.

Status: H-1B visa (expires on 30th Sep 2012).

References

Mr. Tom Patten

Lab Manager

Inter-Mountain Labs

1673 Terra Avenue

Sherida, WY, USA 82801