Supply Chain Vice President

Brian Jackey

*****.*.******@*****.*** 502-***-****

SUMMARY

Results-driven pharma/biotech operations executive with 30+ years of experience leading manufacturing operations, CMC development, supply chain, and quality for both clinical- and commercial-stage organizations. Experienced CDMO site GM and OSD operations director. Co- founded a clinical-stage biotech organization and played a key role in product acquisitions, licensing, and funding strategies.

CORE COMPETENCIES

• Pharma/Biotech Manufacturing & Executive Leadership

• CDMO Site General Management

• Quality, Supply Chain & CMC Development Leadership

• Broad Expertise in OSD, Steriles, Biologics, and Devices PROFESSIONAL EXPERIENCE

EVP, Operations

Arnasi Group (formerly LiquiGlide, Inc) – Cambridge, MA Jul 2023 – Apr 2025

• Led Regulatory Affairs, QA, Supply Chain, HR, Finance, and CMC teams.

• Achieved FDA and Class I medical device registration for ostomy product (Revel).

• Established new manufacturing facility and initiated construction.

• Reduced cost by $1.9M annually through optimized facility transition. SVP, Technical Operations (Co-Founder)

Aceragen, Inc. – Raleigh, NC Apr 2021 – Jun 2023

• Built and led RA, QA, SC, and CMC Development teams from scratch.

• Resolved complex rhAC biologics manufacturing challenges and led mitigation that lifted the FDA clinical hold.

• Enabled Farber Disease clinical trials with optimized CTM production.

• Led diligence, funding, and licensing negotiations. VP, Manufacturing Operations

Graybug Vision – Baltimore, MD Aug 2020 – Apr 2021

• Oversaw construction and qualification of in-house GMP facility.

• Managed CDMO to support GB-102 for Phase 3 trials.

• Prepared for future commercial-scale production. VP, Global Operations and Quality

US WorldMeds – Louisville, KY Apr 2015 – Aug 2020

• Led SC, QA, CMC development, and commercial manufacturing for 8 products.

• Directed CDMO operations and tech transfers across multiple modalities.

• Negotiated 30+ supply and development contracts.

• Reduced COGs by 40% and closed biologics site saving $10M annually. Sr. Director, NA Operations (Site GM)

Aptalis Pharma – Vandalia, OH Apr 2014 – Apr 2015

• Oversaw two CDMO sites with full operational responsibility.

• Implemented OpEx programs across functions and completed $20M site expansion.

• Drove customer service and P&L performance during ownership transition. Director, Plant Operations (and prior leadership roles) UCB Pharma (formerly Schwarz Pharma) – Seymour, IN 1993 – 2014

• Led all manufacturing at 3B+ dosage OSD plant with 300+ staff.

• Implemented advanced OSD technology platforms.

• Directed 20+ product launches, site expansions, and 25+ audits.

• Increased in-stock rates to >99% across 100+ SKUs. Sr. Process Engineer

Bristol-Myers Squibb – Evansville, IN 1992 – 1993

• Led product site transfers and supported tablet/capsule operations. KEY ACCOMPLISHMENTS

• Medical Device: Enabled launch of Class I device via FDA and site registration.

• CMC Development – Biologics: Scaled rhAC enzyme, lifted FDA hold, and enabled FIH study.

• Commercial Supply: Delivered 100% service levels and reduced COGs by 40%.

• CDMO GM: Exceeded performance during ownership changes.

• Generics Launches: Led 15+ generics launches supporting $1.4B business sale.

• Site Expansion: 4x GMP space, 10x capacity, and headcount growth from 200 to 600.

• OSD Tech Transformation: Modernized processes with advanced automation. EDUCATION

BS, Chemical Engineering – Rose-Hulman Institute of Technology, Terre Haute, IN

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