Clinical research scientist

Hyndevi Dokuri, M.B.B.S

Email: ********@*******.*** Phone: 716-***-****

OBJECTIVE

I am a medical doctor currently working as a Research Scholar in the Department of Medicine, Division of Nephrology, at the Jacobs School of Medicine and Biomedical Sciences, University at Buffalo. As both a medical doctor and a research scholar, I am dedicated to advancing translational immunological and clinical medicine through impactful biomedical research. My current work focuses on exploring the molecular mechanisms underlying lupus and kidney disease, with a strong interest in immunomodulation and therapeutic interventions. I aspire to bridge clinical insight with scientific discovery to enhance patient outcomes and promote health equity. EDUCATION

Malla Reddy Medical College for Women, India M.B.B.S, 2014 –2023

• Coursework in Medicine and Surgery

• Distinctions in Anatomy, Physiology, Internal Medicine, and OB/GYN Sri Chaitanya Co-Op Junior College, India 2012–2014

• Biology, Physics, Chemistry

POSITIONS & EMPLOYMENT

Research Scholar

University at Buffalo, Department of Medicine, Division of Nephrology 2023– Present

• Investigating the immunoregulatory role of complement protein Factor H in lupus and chronic kidney disease

• Characterize Flox-Factor H knockout mice using Cre-lox technology to study site-specific complement expression in macrophages and glial cells

• Apply western blotting, immunofluorescence, and genotyping to examine protein expression and immune responses

• Assess kidney and brain function using biochemical markers (albumin, creatinine) and behavioral assays

• Mentor undergraduate students on lab protocols, experimental design, and scientific communication

• Lead studies on the role of complement in blood flow, clotting, and tissue- specific regulation in both acute (sepsis) and chronic disease models Clinical Clerkship Malla Reddy Narayana Multispeciality Hospital, Hyderabad

• Conducted patient history-taking, physical exams, IV cannulation, and wound suturing

• Rotated through Internal Medicine, General Surgery, OB/GYN, and Emergency departments

• Assisted in surgical procedures and deliveries, and provided care in inpatient and outpatient settings

CERTIFICATIONS & ACHIEVEMENTS

• WHO Webinars: Monkeypox Outbreak Response, COVID-19 Emergency Planning, Anaphylaxis Management, Simulation Exercises in Public Health

• Workshops: Clinical ECG Interpretation, Research Methodology, Stress Management in Healthcare

• Gold Medalist – Best Outgoing Girl Student (2012)

• First Class performance in Anatomy, Physiology, Internal Medicine, and OB/GYN

LEADERSHIP & COMMUNITY SERVICE

COVID-19 Relief Initiatives Provided virtual health consultations and follow-up guidance for quarantined patients during the pandemic. Conducted digital awareness campaigns on infection control, vaccination, and early symptom recognition. Remotely monitored vital signs and offered supportive triage advice to help alleviate the burden on in-person health systems.

Public Health Campaigns Actively participated in national and community-based outreach programs, including door-to-door immunization drives for the Pulse Polio Campaign and the Measles-Rubella (MR) Vaccine Initiative. Delivered culturally sensitive education sessions on exclusive breastfeeding and neonatal nutrition to new and expectant mothers in underserved areas.

Blood Donation Drives Led and coordinated voluntary blood donation initiatives at Malla Reddy Medical College. Mobilized peer involvement, designed promotional material, and collaborated with hospital staff to ensure safe collection and community engagement.

RESEARCH EXPERIENCE

Investigating Complement Proteins in Chronic Kidney and Autoimmune Disorders.

Research Scholar Department of Medicine – Division of Nephrology, Jacobs School of Medicine

Investigating Complement Proteins in Chronic Kidney and Autoimmune Disorders As a Research Scholar in Dr. Jessy Alexander’s lab, I study the site-specific function of complement protein Factor H in macrophages and glial cells, using murine models and molecular techniques. My research investigates the systemic and localized role of complement proteins in blood flow, clotting, kidney pathology, and CNS lupus. This work contributes to the development of targeted immunotherapies through in vivo and in vitro analysis.and Biomedical Sciences, University at Buffalo 2023–Present Research Publications

Rajkumar J., Spath A., Dokuri H., Jacob A., Quigg R.J., Alexander J. (2024). Melatonin as a Potential Adjunct Therapy for CNS Lupus. Precision Clinical Medicine, 7(4), pbae024.

Poster Presentations

Dokuri H., Singh H., Jacob A., Alexander J. (2025). Intrinsic Macrophages Factor H in Kidney Homeostasis – AAI Annual Meeting.

Rajkumar J., Spath A., Dokuri H., Alexander J. (2024). Melatonin and SLE Pathology University at Buffalo Annual Research Symposium.

Kanan D., Dokuri H., Alexander J. (2024). Factor H in Kidney Disease – CSTEP Research Symposium.

CONFERENCES ATTENDED

IMMUNOLOGY 2025 – American Association of Immunologists OSMECON 2017 & 2018 – National Undergraduate Medical Conference PACE 2016 – Emergency Medicine Conference

GOMECON 2016 – ECG & Medical Education Workshops

SKILLS

I bring a well rounded skill set that bridges molecular biology techniques with hands on clinical experience and interpersonal strengths. In the lab, I am proficient in western blotting, immunofluorescence, and genotyping, which I regularly apply in immunological and translational research settings. Clinically, I am experienced in conducting patient history taking, performing physical exams, gaining IV access, and carrying out wound suturing with precision. Complementing these technical skills are my soft skills leadership, mentorship, clear communication, and a deeply rooted commitment to compassionate, patient-centered care all of which support effective collaboration and education in both academic and healthcare environments.

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